Molecular genetic studies of chromosome 11 and chromosome 22q DNA sequences in pediatric medulloblastomas

Journal of Neuro-Oncology

Volumn 44, Issue 2, 1999, Pages 119-127

  Lescop, Servane ^a   Lellouch Tubiana, Arielle ^a   Vassal, Gilles ^b   Besnard Guerin, Corinne ^a,c  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c Department of Pediatrics Institut Gustave Roussy ^*  (France)

Author keywords

Chromosomes 11 and 22; Instability; Loss of heterozygosity; Medulloblastoma

Indexed keywords

ARTICLE; CHROMOSOME 11; CHROMOSOME 22Q; CLINICAL ARTICLE; DNA SEQUENCE; GENE DELETION; GENE LOCUS; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MALIGNANT TRANSFORMATION; MEDULLOBLASTOMA; METHYLATION; MOLECULAR GENETICS; PATHOGENESIS; TUMOR SUPPRESSOR GENE;

EID: 0032761061     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006387518100     Document Type: Article

References (45)

1. Plowman PN and Brada M: Paediatric brain tumors. Brit Med Bull 52: 802-817, 1996
2. Bigner SH, Mark J, Friedman HS, Biegel JA, Bigner DD: Structural chromosomal abnormalities in human medulloblastoma. Cane Gent Cytogent 30: 91-101, 1988
3. Griffin CA, Hawkins AL, Packer RJ, Rorke LB, Emanuel BS: Chromosome abnormalities in pediatric brain tumors. Cancer Res 48: 175-180, 1988
4. James CD, Carlbom E, Dumanski JP, Hansen M, Nordenskjold M, Collins VP, Cavenee WK: Clonal genomic alterations in glioma malignancy stages. Cancer Res 48: 5546-5551, 1988
5. Raffel C, Gilles FE, Weinberg KI: Reduction to homozygosity and gene amplification in central nervous system primitive neuroectodermal tumors of childhood. Cancer Res 50: 587-591, 1990
6. Saylor RL, Sidransky D, Friedman HS, Bigner SH, Bigner DD, Volgestein B, Brodeur GM: Infrequent p53 gene mutations in medulloblastomas. Cancer Res 51: 4721-4723, 1991
7. Biegel JA, Burk CD, Barr FG, Emanuel BS: Evidence for a 17p tumor related locus distinct from p53 in pediatric central nervous system primitive neuroectodermal tumors. Cancer Res 52: 3391-3395, 1992
8. Haataja L, Raffel C, Ledbetter DH, Tanigami A, Petersen D, Heisterkamp N: Deletion within the D17S34 locus in a primitive neuroectodermal tumor. Cancer Res 57: 32-34, 1997
9. Scheurlen WG, Seranski P, Mincheva A, Kühl J, SörensenN, Krauss J, Litcher P, Poustka A, Wilgenbus K: High resolution deletion mapping of chromosome arm 17p in childhood primitive neuroectodermal tumors reveals a common chromosomal disruption within the Smith-Magenis region, an unstable region in chromosome band 17p11.2. Gen Chrom Cane 18: 50-58, 1997
10. James CD, He J, Carlbom E, Mikkelsen T, Ridderheim P-A, Cavenee WK, Collins VP: Loss of genetic information in central nervous system tumors common to children and young adults. Gen Chrom Cane 2: 94-102, 1990
11. Fults D, Petronio J, Noblett BD, Pedone CA: Chromosome 11p 15 deletions in human malignant astrocytomas and primitive neuroectodermal tumors. Genomics 14: 799-801, 1992
12. Blacker H, Rasheed BKA, McLendon RE, Friedman HS, Batra SK, Fuchs HE, Bigner S: Microsatellite analysis of childhood brain tumors. Gen Chrom Cane 15: 54-63, 1996
13. Albrecht S, von Deimling A, Pietsh T, Giangaspero F, Brandner S, Kleihuest, Wiestler OD: Micro satellite analysis of loss of heterozygosity on chromosomes 9q, 11p and 17p in medulloblastomas. Neuropathol Appl Neurobiol 20: 74-81, 1994
14. Scheurlen WG, Schwabe GC, Joos S, Mollenhauer J, Sörensen N, Joachim K: Molecular analysis of childhood primitive neuroectodermal tumors defines markers associated with poor outcome. J Clin Oncol 16: 2478-2485, 1998
15. Sonoda Y, lizuka M., Yasuda J, Makino R, Ono T, Kayama T, Yoshimoto T, Sekiya T: Loss of heterozygosity at 11p15 in malignant glioma. Cancer Res 55: 2166-2168, 1995
16. Bepler G, Garcia-Blanco MA: Three tumor-suppressor regions on chromosome lip identified by high-resolution deletion mapping in human non-small-cell lung cancer. Proc Natl Acad Sci USA 91: 5513-5517, 1994
17. Ali U, Lidereau R, Theillet C, Callahan R: Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia. Science 238: 185-188, 1987
18. Koufos A, Grundy P, Morgan K, Aleck KA, Hadro T, Lampkin BC, Kalbakji A, Cavenee WK: Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5. Am J Hum Genet 44: 711-719, 1989
19. Ping AJ, Reeve AE, Law DJ, Young MR, Boehnke M, Feinberg AP: Genetic linkage of Beckwith-Wiedemann syndrome to 11p15. Am J Hum Genet 44: 720-723, 1989
20. Fearon ER, Vogelstein B, Feinberg AP: Somatic deletion and duplication of genes on chromosome 11 in Wilms ' tumours. Nature 309: 176-178, 1984
21. Koufos A, Hansen MF, Lampkin BC, Workman ML, Copeland NG, Jenkins NA, Cavenee WK: Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour. Nature 309: 170-172, 1984
22. Scrable HJ, Witte DP, Lampkin BC, Cavenee WK: Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping. Nature 329: 645-647, 1987
23. Biegel JA, Burck CD, Parmiter AH, Emanuel BS: Molecular analysis of a partial deletion of 22q in a central nervous system rhabdoid tumor. Gen Chrom Cane 5: 104-108, 1992
24. Zang KD: Cytological and cytogenetical studies on human meningioma. Cancer Genet Cytogenet 6: 249-274, 1982
25. Dumanski JP, Carlbom E, Collins VP, Nordenskjöld M: Deletion mapping of a locus on human chromosome 22 involved in the oncogenesis of meningioma. Proc Natl Acad Sci USA 84: 9275-9279, 1987
26. Fain PR, Kort EN, Yousry C, James MR, Litt M: A high resolution CEPH crossover mapping panel and integrated map of chromosome 11. Human Mol Gen 5: 1631-1636, 1996
27. Gessler M, Konig A, Bruns GA: The genomic organization and expression of the WT1 gene. Genomics 12: 807-813, 1992
28. Li Y, Hoang-Xuan K, Delattre J, Poisson, Thomas G, Hamelin R: Frequent loss of heterozygosity on chromosome 9, and low incidence of mutations of cyclin-dependent kinase inhibitors p15 (MTS2) and p16 (MST1) genes in gliomas. Oncogene 11: 597-600, 1995
29. Ohyashiki JH, Ohyashiki K, Aizawa S, Kawakubo K, Shimamoto T, Iwama H, Hayashi S, Toyama K: Replication errors in hematological neoplasias: genomic instability in progression of disease is different among different types of leukemia. Clin Cancer Res 9: 1583-1589, 1996
30. Thomas G, Raffel C: Loss of heterozygosity on 6q, 16q, and 17p in human central nervous system primitive neuroectodermal tumors. Cancer Res 51: 639-643, 1991
31. Aaltonen LA, Peltomaki P, Leach FS, Sistonen P, Pylkkanen L, Mecklin JP, Jarvinen H, Powell SM, Jen J, Hamilton SR, Peterson GM, Kinzler KW, Vogelstein B, de la Chapelle A: Clues to the pathogenesis of familial colorectal cancer. Science 260: 812-816, 1993
32. Thibodeau SN, Bren G, Schaid D: Microsatellite instability in cancer of the proximal colon. Science 260: 816-819, 1993
33. Lonov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363: 558-561, 1993
34. Wooster R, Jansen-Cleton AM, Collins N, Mangion J, Cornelis RS, Cooper CS, Gusterson BA, Ponder BAJ, von Deimling A, Wiestler OD, Cornelisse CJ, Devilee P, Stratton MR: Instability of short tandem repeats (microsatellites) in human cancers. Nature Genetics 6: 152-156, 1994
35. Zhu J, Guo SZ, Beggs AH, Maruayama T, Santarius T, Dasner K, Olsen N, Wu JK, Black P: Micro satellite instability analysis of primary human brain tumors. Oncogene 12: 1417-1423, 1996
36. Amariglio N, Friedman E, Mor O, Stiebel H, Phelan C, Collins P, Nordenkjold M, Brok-Simomi F, Rechavi G: Analysis of microsatellite repeats in pediatric brain tumors. Cancer Gen Cytogenet 84: 56-59, 1995
37. Dams E, Van de Kelft EJZ, Martin JJ, Verlooy J, Willems PJ: Instability of microsatellites in human gliomas. Cancer Res 55: 1547-1549, 1995
38. Izumoto S, Arita N, Ohnishi T, Hiraga S, Taki T, Tomita N, Ohue M, Hayakawa T: Microsatellite instability and mutated type II transforming growth factor-beta receptor gene in gliomas. Cancer Lett J 112: 251-256, 1997
39. Leung SY, Chan TL, Chung LP, Chan AS, Fan YW, Hung KN, Kwong WK, Ho JWC, Yuen ST: Micro satellite instability and mutation of DNA mismatch repair genes in gliomas. Am J Pathol 153: 1181-1188, 1998
40. Kraus JA, Koch A, Albrecht S, Von Deimling A, Wiestler OD, Pietsch T: Loss of heterozygosity at locus F13B on chromosome 1q in human medulloblastoma. Int J Cancer 67: 11-15, 1996
41. Schofield D, West DC, Anthony DC, Marshal R, Sklar J: Correlation of loss of heterozygosity at chromosome 9q with histological subtype in medulloblastomas. Am J Pathol 146: 472-480, 1995
42. Raffel C, Jenkins RB, Frederick L, Hebrink D, Alderete B, Fults DW, James CD: Sporadic medulloblastomas contain PTCH mutations. Cancer Res 57: 842-845, 1997
43. Pietsch T, Waha A, Koch A, Kraus J, Albrecht S, Tonn J, Sorensen N, Berthold F, Henk B, Schmandt N, Wolf HK, von Deimling A, Wainwright B, Chenevix-Trench G, Wiestler OD, Wicking C: Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched. Cancer Res 57: 2085-2088, 1997
44. Wolter M, Reifenberger J, Sommer C, Ruzicka T, Reifenberger G: Mutations in the human homologue of the Drosophila segment polarity gene patched (PTCH) in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res 57: 2581-2585, 1997
45. Smyth I, Narang MA, Evans T, Heimann C, Nakamura Y, Chenevix-Trench G, Pietsch T, Wicking C, Wainwright BJ: Isolation and characterization of human Patched 2 (PTCH2), a putative tumour suppressor gene in basal cell carcinoma and medulloblastoma on chromosome 1p32. Hum Mol Genet 8: 291-297, 1999