Age-related effects of scopolamine on REM sleep regulation in normal control subjects: Relationship to sleep abnormalities in depression

Neuropsychopharmacology

Volumn 21, Issue 6, 1999, Pages 723-730

  Rao, Uma ^a,b   Lutchmansingh, Preetam ^a   Poland, Russell E ^a,b  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adolescents; Adults; Cholinergic; Development; REM sleep; Scopolamine

Indexed keywords

PLACEBO; SCOPOLAMINE;

ADOLESCENT; ADULT; AGE; ARTICLE; CHOLINERGIC SYSTEM; CLINICAL ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; HUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; REGULATORY MECHANISM; REM SLEEP; SLEEP DISORDER; SLEEP PATTERN;

ADOLESCENT; ADULT; AGING; ANALYSIS OF VARIANCE; DEPRESSION; ELECTROENCEPHALOGRAPHY; HUMANS; REFERENCE VALUES; SCOPOLAMINE; SLEEP DISORDERS; SLEEP, REM;

EID: 0032761031     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(99)00067-6     Document Type: Article

References (60)

1. Armitage R., Emslie G., Rintelmann J. The effect of fluoxetine on sleep EEG in childhood depression. A preliminary report Neuropsychopharmacology. 17:1997;241-245.
2. Benca R.M., Obermeyer W.H., Thisted R.A., Gillin J.C. Sleep and psychiatric disorders. Arch Gen Psychiatry. 49:1992;651-668.
3. Berkowitz A., Sutton L., Janowsky D.S., Gillin J.C. Pilocarpine, an orally active muscarinic cholinergic agonist, induces REM sleep and reduces delta sleep in normal volunteers. Psychiatry Res. 33:1990;113-119.
4. Birmaher B., Ryan N.D., Williamson D.E., Brent D.A., Kaufman J. Child and adolescent depression. A review of the past 10 years Part II. J Am Acad Child Adolesc Psychiatry. 35:1996;1575-1583.
5. Borbely A.A. A two process model of sleep regulation. Human Neurobiol. 1:1982;195-204.
6. Cabeza R.D.J., Zoltoski R.K., Gillin J.C. Biochemical pharmacology of sleep. Chokroverty S. Sleep Disorders Medicine. 1994;37-56 Butterworth-Heinemann, Boston, MA.
7. Coyle J.T., Yamamura H. Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain. Brain Res. 118:1976;429-440.
8. Dahl R.E., Ryan N.D., Perel J., Birmaher B., Al-Shabbout M., Nelson B., Puig-Antich J. Cholinergic REM induction test with arecoline in depressed children. Psychiatry Res. 51:1994;269-282.
9. Emslie G, Kowatch R (1996): Predictors of remission and recurrence in depressed children and adolescents. Presented at the 43rd Annual Meeting of the American Academy of Child and Adolescent Psychiatry, Philadelphia, PA, October 22-27.
10. George R., Haslett W.L., Jenden D.J. A cholinergic mechanism in the brainstem reticular formation. Induction of paradoxical sleep Int J Neuropharmacol. 3:1974;541-552.
11. Gillin J.C., Sutton L., Ruiz C., Darko D., Golshan S., Risch S.C., Janowsky D. The effects of scopolamine on sleep and mood in depressed patients with a history of alcoholism and a normal comparison group. Biol Psychiatry. 30:1991;157-169. a.
12. Gillin J.C., Sutton L., Ruiz C., Golshan S., Hirsch S., Warmann C., Shiromani P. Dose dependent inhibition of REM sleep in normal volunteers by biperiden, a muscarinic antagonist. Biol Psychiatry. 30:1991;151-156. b.
13. Gillin J.C., Salin-Pascual R., Velazquez-Moctezuma J., Shiromani P., Zoltoski R. Cholinergic receptor subtypes and REM sleep in animals and normal controls. Cuello A.C. Progress in Brain Research, Vol. 98. 1993;379-387 Elsevier Science Publishers, New York.
14. Gillin J.C., Wyatt R.J., Fram D., Snyder F. The relationship between changes in REM sleep and clinical improvement in depressed patients treated with amitriptyline. Psychopharmacology. 59:1978;267-272.
15. Hamilton M. A rating scale for depression. J Neurol Neursurg Psychiatry. 25:1960;56-62.
16. Hobson J.A., Datta S., Calvo J.M., Quattrochi J. Acetylcholine as a brain state modulator. Triggering and long-term regulation of REM sleep Cuello A.C. Progress in Brain Research, Vol. 98. 1993;389-404 Elsevier Science Publishers, New York.
17. Höchli D., Riemann D., Zulley J., Berger M. Initial REM sleep suppression by clomipramine. A prognostic tool for treatment response in patients with major depressive disorder Biol Psychiatry. 21:1986;1217-1220.
18. Hohagen F., Lis S., Riemann D., Krieger S., Meyer C., Fritsch Montero R., Grunze H., Berger M. Influence of biperiden and bornaprine on sleep in healthy subjects. Neuropsychopharmacology. 11:1994;29-32.
19. Imeri L., Bianchi S., Angeli P., Mancia M. Selective blockade of different brain stem muscarinic receptor subtypes. Effects on the sleep-wake cycle Brain Res. 636:1994;68-72.
20. Jones B.E. The organization of central cholinergic systems and their functional importance in sleep-waking states. Cuello A.C. Progress in Brain Research, Vol. 98. 1993;61-71 Elsevier Science Publishers, New York.
21. Keepers G.A., Clappison V.J., Casey D.E. Initial anticholinergic prophylaxis for acute neuroleptic induced extrapyramidal syndromes. Arch Gen Psychiatry. 40:1983;1113-1117.
22. Knowles J.B., MacLean A.W. Age-related changes in sleep in depressed and healthy subjects. Neuropsychopharmacology. 3:1990;251-259.
23. Kovacs M. Presentation and course of major depressive disorder during childhood and later years of the life span. J Am Acad Child Adolesc Psychiatry. 35:1996;705-715.
24. Kupfer D. REM latency. a psychobiologic marker for primary depressive disease Biol Psychiatry. 11:1976;159-174.
25. Kupfer D.J., Coble P., Kane J., Petti T., Conner C.K. Imipramine and EEG sleep in children with depressive symptoms. Psychopharmacology. 60:1979;117-123.
26. Kupfer D.J., Ehlers C.L., Frank E., Grochocinski V.J., McEachran A.B., Buhari A. Persistent effects of antidepressants. EEG sleep studies in depressed patients during maintenance treatment Biol Psychiatry. 35:1994;781-793.
27. Lauer C.J., Riemann D., Wiegand M., Berger M. From early to late adulthood. Changes in EEG sleep of depressed patients and healthy volunteers Biol Psychiatry. 29:1991;979-993.
28. McCarley R.W., Massaquoi S.G. Neurobiological structure of the revised limit cycle reciprocal interaction model of REM cycle control. J Sleep Res. 1:1992;132-137.
29. McCarley R.W., Greene R.W., Rainnie D., Portas C.M. Brainstem neuromodulation and REM sleep. Sem Neurosci. 7:1995;341-354.
30. McCracken J.T., Poland R.E. Peripubertal and adult rats differ in their hypothalamic-pituitary response to cholinergic challenge. J Child Adolesc Psychopharmacol. 1:1990;141-145.
31. McCracken J.T., Poland R.E., Lutchmansingh P., Edwards C. Sleep electroencephalographic abnormalities in adolescent depressives. Effects of scopolamine Biol Psychiatry. 42:1997;577-584.
32. Mirmiran M., Van De Poll N.E., Corner M.A., Van Oyen H.G., Bour H.L. Suppression of active sleep by chronic treatment with chlorimipramine during early postnatal development. Effects upon adult sleep and behavior in the rat Brain Res. 204:1981;129-146.
33. Myers J.E., Buysse D.J., Thase M.E., Perel J., Miewald J.M., Cooper T.B., Kupfer D.J., Mann J.J. The effects of fenfluramine on sleep and prolactin in depressed inpatients. A comparison of potential indices of brain serotonergic responsivity Biol Psychiatry. 34:1993;753-758.
34. Poland R.E., McCracken J.T., Lutchmansingh P., Lesser I.M., Tondo L., Edwards C., Boone K.B., Lin K.-M. Differential response of rapid eye movement sleep to cholinergic blockade by scopolamine in currently depressed, remitted, and normal control subjects. Biol Psychiatry. 41:1997;929-938.
35. Poland R.E., Tondo L., Rubin R.T., Trelease R.B., Lesser I.M. Differential effects of scopolamine on nocturnal cortisol secretion, sleep architecture, and REM latency in normal volunteers. Relation to sleep and cortisol abnormalities in depression Biol Psychiatry. 25:1989;403-412.
36. Rao U., Dahl R.E., Ryan N.D., Birmaher B., Williamson D.E., Giles D.E., Rao R., Kaufman J., Nelson B. The relationship between longitudinal clinical course, and sleep and cortisol changes in adolescent depression. Biol Psychiatry. 40:1996;474-484.
37. Rechtschaffen A., Kales A. A Manual of Standardized Terminology, Techniques and Scoring System for Sleep Stages of Human Subjects. 1968;Brain Information Service/Brain Research Institute, UCLA, Los Angeles.
38. Riemann D., Berger M. EEG sleep in depression and in remission and the REM sleep response to the cholinergic agonist RS 86. Neuropsychopharmacology. 2:1989;145-152.
39. Riemann D., Joy D., Höchli D., Lauer C., Zulley J., Berger M. Influence of the cholinergic agonist RS 86 on normal sleep. Sex and age effects Psychiatry Res. 24:1988;137-147.
40. Rush A.J., Giles D.E., Jarrett R.B., Feldman-Koffler F., Debus J.R., Weissenburger J., Orsulak P.J., Roffwarg H.P. Reduced REM latency predicts response to tricyclic medication in depressed outpatients. Biol Psychiatry. 26:1989;61-72.
41. Sagalés T., Rill S., Domino E.F. Differential effects of scopolamine and chlorpromazine on REM and NREM sleep in normal male subjects. Clin Pharmacol Therap. 10:1969;522-529.
42. Sagalés T., Rill S., Domino E.F. Effects of repeated doses of scopolamine on the electroencephalographic stages of sleep in normal volunteers. Clin Pharmacol Therap. 18:1975;727-732.
43. Salin-Pascual R.J., Granados-Fuentes D., Galicia-Polo Nieves E., Gillin J.C. Development of tolerance after repeated administration of a selective muscarinic M1 antagonist biperiden in healthy human volunteers. Biol Psychiatry. 33:1993;188-193.
44. 1A receptor probes in patients with major depression and in normal controls. Biol Psychiatry. 44:1998;21-33.
45. Shain B.N., Naylor M., Shipley J.E., Alessi N. Imipramine effects on sleep in depressed adolescents. A preliminary report Biol Psychiatry. 28:1990;459-462.
46. Sharpley A.L., Cowen P.J. Effect of pharmacologic treatments on the sleep of depressed patients. Biol Psychiatry. 37:1995;85-98.
47. Shiromani P.J., Gillin J.C. Acetylcholine and the regulation of REM sleep. Basic mechanisms and clinical implications for affective illness and narcolepsy Ann Rev Pharmacol Toxicol. 27:1987;137-156.
48. Siegel J.M. Brainstem mechanisms generating REM sleep. Kryger M.H., Roth T., Dement W.C. Principles and Practice of Sleep Medicine. 1994;125-144 W.B. Saunders Company, Philadelphia, PA.
49. Sitaram N., Gillin J.C. Development and use of pharmacological probes of the CNS in man. Evidence of cholinergic abnormality in primary affective illness. Biol Psychiatry. 15:1980;925-955.
50. Sitaram N., Mendelson W.B., Wyatt R.J., Gillin J.C. The time-dependent induction of REM sleep and arousal by physostigmine infusion during normal human sleep. Brain Res. 122:1977;562-567.
51. Sitaram N., Moore A.M., Gillin J.C. Induction and resetting of REM sleep rhythm in normal man by arecholine. Blockade by scopolamine Sleep. 1:1978;83-90.
52. Spitzer R.L., Williams J.B.W., Gibbons M. The Structured Clinical Interview for DSM-III-R (SCID). 1986;New York State Psychiatric Research Institute, New York.
53. Staner L., Kerkhofs M., Detroux D., Leyman S., Linkowski P., Mendlewicz J. Acute, subchronic and withdrawal sleep EEG changes during treatment with paroxetine and amitriptyline. A double-blind randomized trial in major depression Sleep. 18:1995;470-477.
54. Sutin E.L., Shiromani P.J., Kelsoe J.R., Storch F.I., Gillin J.C. Rapid-eye movement sleep and muscarinic receptor binding in rats are augmented during withdrawal from chronic scopolamine treatment. Life Sci. 39:1986;2419-2427.
55. Thase M.E., Buysse D.J., Frank E., Cherry C.R., Cornes C.L., Mallinger A.G., Kupfer D.J. Which depressed patients will respond to interpersonal psychotherapy? The role of electroencephalographic sleep profiles. Am J Psychiatry. 154:1997;502-509.
56. Teicher M.H., Glod C.A., Harper D., Magnus E., Brasher C., Wren F., Pahlavan K. Locomotor activity in depressed children and adolescents. I. Circadian dysregulation J Am Acad Child Adolesc Psychiatry. 32:1993;760-769.
57. Velazquez-Moctezuma J., Gillin J.C., Shiromani P.J. Effect of specific M1, M2 muscarinic receptor agonists on REM sleep generation. Brain Res. 503:1989;128-131.
58. Velazquez-Moctezuma J., Shalauta M., Gillin J.C., Shiromani P.J. Cholinergic antagonists and REM sleep generation. Brain Res. 543:1991;175-179.
59. Vogel G.W., Buffenstein A., Minter K., Hennessey A. Drug effects on REM sleep and on endogenous depression. Neurosci Beh Rev. 14:1990;49-63.
60. 1 muscarinic antagonists on rapid eye movement sleep. Brain Res. 608:1993;186-190.