Significant role of neuronal non-N-type calcium channels in the sympathetic neurogenic contraction of rat mesenteric artery

British Journal of Pharmacology

Volumn 128, Issue 7, 1999, Pages 1602-1608

  Tanaka, Yoshio ^a   Mochizuki, Yumi ^a   Tanaka, Hikaru ^a   Shigenobu, Koki ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

Ca2+ channels, N type; Ca2+ channels, P type; Ca2+ channels, Q type; Rat mesenteric artery; Sympathetic nerve transmission; agatoxin IVA; conotoxin GVIA; conotoxin MVIIC

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; GUANETHIDINE; NORADRENALIN; OMEGA AGATOXIN IVA; OMEGA CONOTOXIN GVIA; PRAZOSIN; TETRODOTOXIN;

ADRENERGIC TRANSMISSION; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CONTROLLED STUDY; ELECTRIC FIELD; MALE; MESENTERIC ARTERY; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYMPATHETIC NERVE;

EID: 0032757597     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702954     Document Type: Article

References (22)

1. CLASBRUMMEL, B., OSSWALD, H. & ILLES, P. (1989). Inhibition of noradrenaline release by ω-conotoxin-GVIA in the rat tail artery. Br. J. Pharmacol., 96, 101-110.
2. 2+ channels in neurotransmission in the rat urinary bladder. Br. J. Pharmacol., 116, 1595-1598.
3. 2+ channels. Neuron, 9, 69-77.
4. 2+ channels in evoked release of norepinephrine from sympathetic neurons. Science, 239, 57-61.
5. LUNDY, P.M. & FREW, R. (1994). Effect of ω-agatoxin IVA on autonomie neurotransmission. Eur. J. Pharmacol., 261, 79-84.
6. MASUYAMA, Y., TSUDA, K., KUSUYAMA, Y., HANO, T., KUCHII, M. & NISHIO, I. (1984). Neurotransmitter release, vascular responsiveness and their calcium-mediated regulation in perfused mesenteric preparation of spontaneously hypertensive rats and DOCA-salt hypertension. J. Hypertens., 2 (Suppl.): S99-S102.
7. MCCLESKEY, E.W., FOX, A.P., FELDMAN, D.H., CRUZ, L.J., OLIVERA, B.M., TSIEN, R.W. & YOSHIKAMI, D. (1987). ω-Conotoxin: Direct and persistent blockade of specific types of calcium channels in neurons but not muscle. Proc. Natl. Acad. Sci. U.S.A., 84, 4327-4331.
8. MINTZ, I.M., ADAMS, M.E. & BEAN, B.P. (1992a). P-type calcium channels in rat central and peripheral neurons. Neuron, 9, 85-95.
9. MINTZ, I.M., VENEMA, V.J., SWIDEREK, K.M., LEE, T.D., BEAN, B.P. & ADAMS, M.E. (1992b). P-type calcium channels blocked by the spider toxin ω-Aga-IVA. Nature, 355, 827-829.
10. MIRGORODSKY, V.N. & SKOK, V.I. (1969). Intracellular potentials recorded from a tonically active mammalian sympathetic ganglion. Brain Res., 15, 570-572.
11. OLIVERA, B.M., MCINTOSH, J.M., CRUZ, L.J., LUQUE, F.A. & GRAY, W.R. (1984). Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. Biochemistry, 23, 5087-5090.
12. OLIVERA, B.M., MILJANICH, G.P., RAMACHANDRAN, J. & ADAMS, M.E. (1994). Calcium channel diversity and neurotransmitter release: The ω-conotoxins and ω-agatoxins. Annu. Rev. Biochem., 63, 823-867.
13. PARKER, R.B. & WAUD, D.R. (1971). Pharmacological estimation of drug-receptor dissociation constants. Statistical evaluation. I. Agonist. J. Pharmacol. Exp. Ther., 177, 1-12.
14. PRUNEAU, D. & ANGUS, J.A. (1990). ω-Conotoxin GVIA is a potent inhibitor of sympathetic neurogenic responses in rat small mesenteric arteries. Br. J. Pharmacol., 100, 180-184.
15. REN, L.-M., NAKANE, T. & CHIBA, S. (1994). Differential effects of ω-conotoxin GVIA and tetrodotoxin on vasoconstrictions evoked by electrical stimulation and nicotinic receptor stimulation in canine isolated, perfused splenic arteries. Br. J. Pharmacol., 111, 1321-1327.
16. 1 subunits. Neuron, 11, 291-303.
17. SMITH, S.J. & AUGUSTINE, G.J. (1988). Calcium ions, active zones and synaptic transmitter release. Trends Neurosci., 11, 458-464.
18. Ca channel activation in atrial natriuretic peptide-induced vasorelaxation. Naunyn-Schmiedeberg's Arch. Pharmacol., 357, 705-708.
19. 2+ channels in supporting bippocampal synaptic transmission. Science, 264, 107-111.
20. WHORLOW, S.L., ANGUS, J.A. & WRIGHT, C.E. (1996). Selectivity of ω-conotoxin GVIA for N-type calcium channels in rat isolated small mesenteric arteries. Clin. Exp. Pharmacol. Physiol., 23, 16-21.
21. WRIGHT, C.E. & ANGUS, J.A. (1996). Effects of N-, P-and Q-type neuronal calcium channel antagonists on mammalian peripheral neurotransmission. Br. J. Pharmacol., 119, 49-56.
22. ZYGMUNT, P.M. & HOGESTATT, E.D. (1993). Calcium channels at the adrenergic neuroeffector junction in the rabbit ear artery. Naunyn-Schmiedeberg's Arch. Pharmacol., 347, 617-623.