Susceptibility of rhDNase I to glycation in the dry-powder state

Analytical Chemistry

Volumn 71, Issue 20, 1999, Pages 4445-4454

  Quan, Cynthia P ^a   Wu, Sylvia ^a   Dasovich, Nancy ^a   Hsu, Chung ^a   Patapoff, Tom ^a   Canova Davis, Eleanor ^a  

^a GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DORNASE ALFA; LACTOSE; LYSINE; SUGAR;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CHEMICAL REACTION; DRY POWDER; GLYCATION; PROTEIN STRUCTURE; REACTOR;

AMINO ACID SEQUENCE; DEOXYRIBONUCLEASE I; DESICCATION; GLUCOSE; LACTOSE; MOLECULAR SEQUENCE DATA; POWDERS; RECOMBINANT PROTEINS;

EID: 0032755910     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac9900580     Document Type: Article

References (32)

1. Randolph, T. W. J. Pharm. Sci. 1997, 86 (11), 1198-1203.
2. Gottschalk, A. Glycoproteins, Their Composition, Structure and Function, 2nd ed.; Elsevier: New York, 1972; pp 141-157.
3. Furth, A. J. Anal. Biochem. 1988, 27, 347-360.
4. Shak, S.; Capon, D. J.; Hellmiss, R.; Marsters, S. A.; Baker, C. L. Proc. Natl. Acad. Sci. U.S.A. 1990, 87, 9188-9192.
5. Cipolla, D.; Gonda, I.; Shire, S. J. Pharm. Res. 1994, 11, 491-498.
6. Mrsny, R. J.; Lazazzera, B. A.; Daugherty, A. L.; Schiller, N. L.; Patapoff, T. W. Pulm. Pharm. 1994, 7, 352-366
7. Cacia, J.; Quan, C. P.; Vasser, M.; Sliwkowski, M. B.; Frenz, J. J. Chromatogr. 1993, 634, 229-239.
8. Frenz, J.; Quan, C. P.; Cacia, J.; Democko, C.; Bridenbaugh, R.; McNerney, T. Anal. Chem. 1994, 66, 335-340.
9. Quan, C. P.; Cacia, J.; Frenz, J.; O'Connor, J. V. Pharm. Sci. 1997, 3, 53-57.
10. Weston, S. A.; Lahm, A.; Suck, D. J. Mol. Biol. 1992, 226, 1237-1256.
11. Williams, R. W., J. Mol. Biol. 1983, 166, 581-603.
12. Przybycien, T. M.; Bailey, J. E. Biochim. Biophys. Acta 1989, 995, 231-245.
13. Costantino, H. R.; Andya, J. D.; Shire, S. J.; Hsu, C. C. Pharm. Sci. 1997, 3, 121-128.
14. Byler, D. M.; Susi, H. Biopolymers 1986, 25, 469-487.
15. Dong, A.; Prestrelski, S. J.; Allison, S. D.; Carpenter, J. F. J. Pharm. Sci. 1995, 84, 415-424.
16. Griebenow, K.; Klibanov, A. M. Biotechnol. Bioeng. 1997, 53, 351-362.
17. Allen, G. Sequencing of Proteins and Peptides, Elsevier/North Holland Biomedical Press: New York, 1981; pp 53-58.
18. Kunitz, M. J. Gen. Physiol. 1950, 33, 349-361.
19. Shapiro, R.; McManus, M. J.; Zalut, C.; Bunn H. F. J. Biol. Chem. 1980, 255, 3120-3127.
20. Garlick, R. L.; Mazer, J. S. J. Biol. Chem. 1983, 258, 6142-6146.
21. Watkins, N. G.; Thorpe, S. R.; Baynes, J. W. J. Biol. Chem. 1985, 260, 10629-10636.
22. Iberg, N.; Flückiger, R. J. Biol. Chem. 1985, 261, 13542-13545.
23. Watkins, N. G.; Neglia-Fisher, C. I.; Dyer, D. G.; Thorpe, S. R.; Baynes, J. W. J. Biol. Chem. 1987, 262, 7207-7212.
24. Flückiger, R.; Strang, C. J. Protein Science 1995, 4, 186.
25. Shilton, B. H.; Walton, D. J. J. Biol. Chem. 1991, 266, 5587-5592.
26. Cantor, C. R.; Schimmel, P. R. Biophysical Chemistry Part I: The Conformation of Biological Macromolecules, W. H. Freeman & Co., 1980; pp 41-51,
27. Yang, A.-S.; Gunner, M. R.; Sampogna, R.; Sharp, K.; Honig, B. Proteins: Struct., Funct., Genet. 1993, 15, 252-265.
28. Suck, D.; Oefner, C.; Kabsch, W. EMBO J. 1984, 10, 2423-2430.
29. Wolf, E.; Frenz, J.; Suck, D. Protein Engineering 1995, 8, 79
30. Perrin, D. D. Dissociation Constants of Organic Bases in Aqueous Solution, IUPAC, Analytical Chemistry division, 1965.
31. Carpenter, J. F.; Arakawa, T.; Crowe, J. H. Dev. Biol. Stand. 1990, 74, 225-239
32. Clark, A. R.; Dasovich, N.; Gonda, I.; Chan, H.-K. Respiratory Drug Delivery V; Interpharm Press, Inc.: Buffalo Grove, IL, 1996; pp 167-174.