High frequency of deletion on chromosome 9p21 may harbor several tumor- suppressor genes in human prostate cancer

International Journal of Cancer

Volumn 83, Issue 5, 1999, Pages 610-614

  Perinchery, Geetha ^a   Bukurov, Nikola ^a   Nakajima, Koichi ^a   Chang, James ^a   Li, Long Cheng ^a   Dahiya, Rajvir ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED CANCER; ARTICLE; CANCER GRADING; CANCER STAGING; CARCINOGENESIS; CHROMOSOME 9P; CHROMOSOME DELETION; CLINICAL ARTICLE; CONTROLLED STUDY; GENE LOCUS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE EPITHELIUM; TUMOR SUPPRESSOR GENE;

CHROMOSOMES, HUMAN, PAIR 9; GENES, TUMOR SUPPRESSOR; GENETIC MARKERS; HUMANS; LOSS OF HETEROZYGOSITY; MALE; NEOPLASM STAGING; POLYMERASE CHAIN REACTION; PROSTATIC NEOPLASMS;

EID: 0032755478     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19991126)83:5<610::AID-IJC7>3.0.CO;2-2     Document Type: Article

References (20)

1. CAIRNS, P. and 18 OTHERS, Frequency of homozygous deletion at p16/ CDKn2 in primary human tumors. Nature (Genet.), 11, 210-212 (1995).
2. CANNON-ALBRIGHT, L. and EELES, R., Progress in prostate cancer. Nature (Genet.), 9, 336-338 (1995).
3. CHEN, W., WEGHORST, C.M., SABOURIN, C.L., WANG, Y., WANG, D., BOSTWICK, D.G. and STONER, G.D., Absence of p16/MTS1 gene mutations in human prostate cancer. Carcinogenesis, 17, 2603-2607 (1996).
4. CHER, M.L., BOVA, G.S., MOORE, D.H., SMALL, E.J., CARROLL, P.R., PIN, S.S., EPSTEIN, J.I., ISAACS, W.B. and JENSEN, R.H., Genetic alterations in untreated metastatic and androgen independent prostate cancer detected by comparative genomic hybridization and allelotyping. Cancer Res., 56, 3091-3102 (1996).
5. DAHIYA, R., MCCARVILLE, J., LEE, C., HU, W.-X., CHUI, R.M., KAUR, G. and DENG, G., Chromosome 3p24-26 and 3p22-12 loss in human prostatic adenocarcinoma. Int. J. Cancer, 71, 20-25 (1997a).
6. DAHIYA, R., MCCARVILLE, J., LEE, C., HU, W.-X., KAUR, G., CARROLL, P. and DENG, G., Deletion on chromosome 11p15, p12, q22, q23-24 loci in human prostate cancer. Int. J. Cancer, 72, 283-288 (1997b).
7. DEVLIN, J., KEEN, A.J. and KNOWLES, M.A., Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region 2cM of IFNA. Oncogene, 9, 2757-2760 (1994).
8. GADDIPATI, J.P., MCLEOD, D.G., SESTERHENN, I.A., HUSSUSSIAN, C.J., TONG, Y.A., SETH, P., DRACOPOLI, N.C., MOUL, J.W. and SRIVASTAVA, S., Mutations of the p16 gene product are rare in prostate cancer. Prostate, 30, 188-194 (1997).
9. GU, K., MES-MASSON, A.M., GAUTHIER, J. and SAAD, F., Analysis of the p16 tumor suppressor gene in early-stage prostate cancer. Mol. Carcinogenesis, 21, 164-170 (1998).
10. JARRARD, D.F., BOVA, G.S., EWING, C.M., PIN, S.S., NGUYEN, S.H., BAYLIN, S.B., CAIRNS, P., SIDRANSKY, D., HERMAN, J.G. and ISAACS, W.B., Deletional, mutational, and methylation analyses of CDKN2(p16/MTS1) in primary and metastatic prostate cancer. Genes Chromosomes Cancer, 19, 90-96 (1997).
11. JOOS, S., BERGERHEIM, U.S.R., PAN, Y., MATSUYAMA, H., BENTZ, M., DUMANOIR, S. and LICHTER, P., Mapping of chromosomal gains and losses in prostate cancer by comparative genomic hybridization. Genes Chromosomes Cancer, 14, 267-276 (1995).
12. LUNDGREN, R., MANDAHL, N., LIMON, J., HENRIKSON, H. and MITELMAN, F., Cytogenetic analysis of 57 primary prostatic adenocarcinomas. Genes Chromosomes Cancer, 4, 16-24 (1992).
13. MANGOLD, K.A., TAKAHASHI, H., BRANDIGI, C., WADA, T., WAKUI, S., FURUSATO, M., BOYD, J., CHANDLER, F.W. and ALLSBROOK, W.C., Jr., p16 (CDKN2/MTS1) gene deletions are rare in prostatic carcinomas in the United States and Japan. J. Urol., 157, 1117-1120 (1997).
14. OKAMI, K., CAIRNS, P., WESTRA, W.H., LINN, J.F., AHRENDT, S.A., WU, L., SIDRANSKY, D. and JEN, J., Detailed deletion mapping at chromosome 9p21 in non-small cell lung cancer by microsatellite analysis and fluorescence in situ hybridization. Int. J. Cancer, 74, 588-592 (1997).
15. OLOPADE, O.I., POMYKALA, H.M., HAGOS, F., SVEEN, L.W., ESPINOSA, R., DREYLING, M.H., GURSKY, S., STADLER, W.M., LE BEAU, M.M. and BOHLANDER, S.K., Construction of a 2.8 megabase YAC contig and cloning of the methyladenosme phosphorylase (MTAP) gene from a tumor suppressor region on 9p21. Proc. nat. Acad. Sci. (Wash.), 92, 6489-6493 (1995).
16. TAMIMI, Y., BRINGUIER, P.P., SMIT, F., VAN BOKHOVEN, A., DEBRUYNE, F.M. and SCHALKEN, J.A., p16 mutations/deletions are not frequent events in prostate cancer. Brit. J. Cancer, 74, 120-122 (1996).
17. VISAKROPI, T., KALLIONIEMI, A.H., SYVANEN, A.C., HYYTINEN, E.R., KARHU, R., TAMMELA, T., ISOLA, J.J. and KALLIONIEMI, O.P., Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization. Cancer Res., 55, 342-347 (1995).
18. WABER, P., DLUGOSZ, S., CHENG, Q.C., TRUELSON, J. and NISEN, P.D., Genetic alterations of chromosome band 9p21-22 in head and neck cancer are not restricted to p16INK4a. Oncogene, 15, 1699-1704 (1997).
19. WILLIAMS, B.J., JONES, E. and BROTHMAN, A.R., Homologous centromere association of chromosomes 9 and 17 in prostate cancer. Cancer Genet. Cytogenetics, 85, 143-152 (1995).
20. WILLIAMS, B.J., JONES, E., KOZLOWSKJ, J.M., VESSELLA, R. and BROTHAM, A.R., Comparative genomic hybridization and molecular cytogenetic characterization of two prostate cancer xenografts. Genes Chromosomes Cancer, 18, 299-304 (1997).