Skeletal malformations associated with congenital diaphragmatic hernia: Experimental and human studies

Journal of Pediatric Surgery

Volumn 34, Issue 11, 1999, Pages 1624-1629

  Migliazza, Lucia ^a,b   Xia, Huimin ^a,b   Diez Pardo, Juan A ^a,b   Tovar, Juan A ^a,b  

^a Hospital Infantil La Paz ^*

^b HOSPITAL INFANTIL LA PAZ   (Spain)

Author keywords

Congenital diaphragmatic hernia; Limb; Malformation; Nitrofen; Rat; Vertebra

Indexed keywords

NITROFEN;

ANIMAL MODEL; BONE MALFORMATION; CONFERENCE PAPER; CONGENITAL MALFORMATION; CONTROLLED STUDY; DIAPHRAGM HERNIA; DISEASE ASSOCIATION; EMBRYO DEVELOPMENT; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; MULTIPLE MALFORMATION SYNDROME; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032752589     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-3468(99)90630-9     Document Type: Conference Paper

References (27)

1. Puri P, German F: Lethal nonpulmonary anomalies associated with congenital diaphragmatic hernia: Implications for early intrauterine surgery. J Pediatr Surg 19:29-32, 1984
2. Benjamin DR, Juul S, Siebert JR: Congenital posterolateral diaphragmatic hernia: Associated malformations. J Pediatr Surg 23:899-903, 1988
3. Sweed Y, Puri P: Congenital diaphragmatic hernia: Influence of associated malformations on survival. Arch Dis Child 69:68-70, 1993
4. Fauza DO, Wilson JM: Congenital diaphragmatic hernia and associated anomalies: Their incidence, identification, and impact on prognosis. J Pediatr Surg 29:1113-1117, 1994
5. Losty PD, Vanamo K, Rintala RJ, et al: Congenital diaphragmatic hernia - Does the side of the defect influence the incidence of associated malformations? J Pediatr Surg 33:507-510, 1998
6. Xia H, Diez-Pardo JA, Possögel AK, et al: Skeletal malformations in the adriamycin rat model of esophageal atresia. J Pediatr Surg (in press)
7. Ojeda JL, Barbosa E, Gomez Bosque P: Selective skeletal staining in whole chicken embryos: A rapid Alcian Blue technique. Stain Techn 45:137-138, 1970
8. Simons EV, Van Horn JR: A new procedure for whole-mount alcian blue staining of the cartilaginous skeleton of chicken embryos, adapted to the clearing procedure in potassium hydroxide. Acte Morph Neerl- Scand 8:281-292, 1970/1971
9. Migliazza L, Otten C, Xia H, et al: Heart hypoplasia in experimental congenital diaphragmatic hernia in rats. J Pediatr Surg 34:706-711, 1999
10. Migliazza L, Otten C, Xia H, et al: Cardiovascular malformations in experimental diaphragmatic hernia. J Pediatr Surg (in press)
11. Iritani I: Experimental study on embryogenesis of congenital diaphragmatic hernia. Anat Embryol 169:133-139, 1984
12. Kluth D, Tenbrinck R, Vonekesparre M, et al: The natural history of congenital diaphragmatic hernia and pulmonary hypoplasia in the embryo. J Pediatr Surg 28:456-463, 1993
13. Larsen WJ: Human Embryology (ed 2), New York, NY, Churchill Livingstone, 1997
14. Kluth D, Keijzer R, Hertl M, et al: Embryology of congenital diaphragmatic hernia. Sem Pediatr Surg 5:224-233, 1996
15. Alles AJ, Losty PD, Donahoe PK, et al: Embryonic cell death patterns associated with nitrofen-induced congenital diaphragmatic hernia. J Pediatr Surg 30:353-360, 1995
16. Allan DW, Greer JJ: Pathogenesis of nitrofen-induced congenital diaphragmatic hernia in fetal rats. J Appl Physiol 83:338-347, 1997
17. Vanamo K, Peltonen J, Rintala R, et al: Chest wall and spinal deformities in adults with congenital diaphragmatic defects. J Pediatr Surg 31:851-854, 1996
18. McCredie J, Reid IS: Congenital diaphragmatic hernia associated with homolateral upper limb malformation: A study of possible pathogenesis in four cases. J Pediatr 92:762-765, 1978
19. Lerone M, Soliani M, Corea D, et al: Congenital diaphragmatic hernia associated with ipsilateral upper limb reduction defects. Am J Med Genet 44:827-829, 1992
20. Martinez-Frias ML, Prieto L, Urioste M, et al: Clinical/ epidemiological analysis of congenital anomalies associated with diaphragmatic hernia. Am J Med Genet 62:71-76, 1996
21. Qi B, Diez-Pardo JA, et al: Experimental ureterohydronephrosis in fetal rats. J Pediatr Surg 31:1247-1251, 1996
22. Qi B, Diez-Pardo JA, Nistal M, et al: Testicular maldescent and maldevelopment in fetal rats prenatally exposed to nitrofen. Pediatr Surg Int 11:261-265, 1996
23. Xia H, Otten C, Migliazza L, et al: Tracheobronchial malformations in experimental diaphragmatic hernia. J Pediatr Surg 34:536-539, 1999
24. Alfonso LF, Vilanova J, Aldazábal P, et al: Lung growth and maturation in the rat model of experimentally induced congenital diaphragmatic hernia. Eur J Pediatr Surg 3:6-11, 1993
25. Alfonso LF, Arnaiz A, Alvarez FJ, et al: Lung hypoplasia and surfactant immaturity induced in the fetal rat by prenatal exposure to nitrofen. Biol Neonate 69:94-100, 1996
26. Mark M, Rijli FM, Chambon P: Homeobox genes in embryogenesis and pathogenesis. Pediatr Res 42:421-429, 1997
27. Losada A, Xia H, Migliazza L, et al: Lung hypoplasia caused by nitrofen is mediated by down-regulation of the transcription factor TTF-1. Pediatr Surg Int 15:188-191, 1999