Pharmacokinetics of rifabutin in HIV-infected patients with or without wasting syndrome

British Journal of Clinical Pharmacology

Volumn 48, Issue 5, 1999, Pages 704-711

  Gatti, G ^a,b   Di Biagio, A ^a   De Pascalis, C R ^a   Guerra, M ^a   Bassetti, M ^a   Bassetti, D ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

HIV infection; Rifabutin; Wasting syndrome

Indexed keywords

DIDANOSINE; METHADONE; PENTAMIDINE; RIFABUTIN; ZIDOVUDINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG HALF LIFE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; PRIORITY JOURNAL; WASTING SYNDROME;

ADULT; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; BIOLOGICAL MARKERS; FEMALE; HIV INFECTIONS; HIV WASTING SYNDROME; HUMANS; MALE; RIFABUTIN; XYLOSE;

EID: 0032752474     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1999.00069.x     Document Type: Article

References (29)

1. 1 Tett S, Moore S, Ray J. Pharmacokinetics and bioavailability of fluconazole in two groups of males with human immunodeficiency virus infection compared with those in a group of males without HIV infection. Antimicrob Agents Chemother 1995; 39: 1835-1841.
2. 2 Shelton M, Adams J, Hewitt R, et al. Reduced delavirdine exposure in HIV+ subjects with gastric hypoacidity. In Program and Abstract of 35th Intersc Conf Antimicrob Agents Chemother, San Francisco, CA 1995 Abstract A30. American Society for Microbiology, Washington, DC.
3. 3 Gatti G, Flaherty J, Bubp J, White J, Borin M, Gambertoglio JG. Comparative study of bioavailabilities and pharmacokinetics of clindamycin in healthy volunteers and patients with AIDS. Antimicrob Agents Chemother 1993; 37: 1137-1143.
4. 4 Gordon SM, Horsburgh CR, Peloquin CA, et al. Low serum levels of oral antimycobacterial agents in patients with disseminated Mycobacterium avium complex disease. J Infect Dis 1993; 168: 1559-1562.
5. 5 Lake-Bakaar G, Winston T, Lake-Bakaar D, et al. Gastropathy and ketoconazole malabsorption in the acquired immunodeficiency syndrome (AIDS). Ann Int Med 1988; 109: 471-473.
6. 6 Crivat M, Vittecoq D, Kodjo A, et al. Pharmacokinetic of saquinavir and study of intestinal function in HIV patients. In Program and Abstract of 37th Intersc Conf Antimicrob Agents Chemother, Toronto, Canada 1997 Abstract A9. American Society for Microbiology, Washington, DC.
7. 7 Macnab KA, Gill MJ, Sutherland LR, De Boer Visser N, Church D. Erratic zidovudine bioavailability in HIV seropositive patients. J Antimicrob Chemother 1993; 31: 421-428.
8. 8 Chin TWF, Vandenbroucke A, Fong IW. Pharmacokinetics of trimethoprim-sulfamethoxazole in critically ill and non-critically ill AIDS patients. Antimicrob Agents Chemother 1995; 39: 28-33.
9. 9 Choudhri SH, Hawken M, Gathua S, et al. Pharmacokinetics of antimycobacterial drugs in patients with tuberculosis, AIDS and diarrhea. Clin Infect Dis 1997; 25: 104-111.
10. 10 Smith PD, Quinn TC, Strober W, Janoff EN, Masur H. Gastrointestinal infections in AIDS. Ann Int Med 1992; 116: 63-77.
11. 11 Ullrich R, Zeitz M, Heise W, L'age M, Hoffken G, Riecken EO. Small intestinal structure and function in patients infected with human immunodeficiency virus (HIV): evidence for HIV-induced enteropathy. Ann Int Med 1989; 111: 15-21.
12. 12 Kotler DP, Gaetz HP, Lange M. Enteropathy associated with the acquired immunodeficiency syndrome. Ann Int Med 1984; 101: 421-428.
13. 13 Gillin JS, Shike M, Alcock N, et al. Malabsorption and mucosal abnormalities of the small intestine in the acquired immunodeficiency syndrome. Ann Int Med 1985; 102: 619-622.
14. 14 Washington CB, Duran GE, Sikic BI, Blaschke TF. Saquinavir is a high affinity substrate for the multidrug transpoter, P-glycoprotein. Clin Pharmacol Ther 1997; 61: 193.
15. 15 Narang PK. Clinical pharmacology of rifabutin: a new antimycobacterial. Rev Cont Pharmacother 1995; 6: 129-151.
16. 16 Colborn D, Lewis R, Narang PK. HIV disease severity does not influence rifbutin absorption. In Program and Abstract of 34th Int Conf on Antimicrob Agents Chemother, Orlando, FL 1994 Abstract A42. American Society for Microbiology, Washington, DC.
17. 17 Narang PK. Rifabutin oral absorption unaltered with progressing HIV disease. Clin Pharmacol Ther 1996; 59: 141.
18. 18 Eberts TJ, Sample RH, Glick MR, Ellis GH. A simplified, colorimetric micromethod for xylose in serum or urine, with phloroglucinol. Clin Chem 1979; 25: 1440-1443.
19. 19 Kotler DP, Tierney AR, Brenner SK. Preservation of short-term energy balance in clinically stable patients with AIDS. Am J Clin Nutr 1990; 51: 7-13.
20. 20 Melchior JC, Salmon D, Rigaud D. Resting energy expenditure is increased in stable, malnourished, HIV-infected patients. Am J Clin Nutr 1991; 53: 437-441.
21. 21 Bjarnason I, Sharpstone DR, Francis N, et al. Intestinal inflammation, ileal structure and function in HIV. AIDS 1996; 10: 1385-1391.
22. 22 Harriman GR, Smith PD, Horne MDK, et al. Vitamin B12 malabsorption in patients with acquired immunodeficiency syndrome. Arch Int Med 1989; 149: 2039-2041.
23. 23 Connolly GM, Forbes A, Gazzard BG. Investigation of seemingly pathogen-negative diarrhea in patients infected with HIV1. Gut 1990; 31: 886-889.
24. 24 Ehrenpreis ED, Gulino SP, Patterson BK, Craig RM, Yokoo H, Atkinson AJ. Kinetics of D-xylose absorption in patients with human immunodeficiency virus enteropathy. Clin Pharmacol Ther 1991; 49: 632-640.
25. 25 Colborn DC, Li RC, Narang PK. Influence of gender on rifabutin kinetics. Clin Pharmacol Ther 1993; 53: 182.
26. 26 Narang PK, Li RC, Colborn D, Bianchine JR. Gender influence on rifabutin pharmacokintics. AIDS 1992 6(Suppl)Int Congress Glasgow UK.
27. 27 Duchene P. Pharmacokinetics of rifabutin (LM427) in patients with alcoholic liver disease. Internal Report LM 427/613i 1990 Milan: Farmitalia Carlo Erba.
28. 28 Chlebowski RT, Grosvenor M, Lillington L, Sayre J, Beall G. Dietary intake and counseling, weight maintenance, and the course of HIV infection. J Am Diet Ass 1995; 95: 428-432.
29. 29 Suttman U, Ockenga J, Selberg O, Hoogestraat L, Deicher H, Muller MJ. Incidence and prognostic value of malnutrition and wasting in human immunodeficiency virus-infected outpatients. J AIDS Human Retrovirol 1995; 8: 239-246.