The anhydrous milk fat, ghee, lowers serum prostaglandins and secretion of leukotrienes by rat peritoneal macrophages

Prostaglandins Leukotrienes and Essential Fatty Acids

Volumn 61, Issue 4, 1999, Pages 249-254

  Vijaya Kumar, M ^a   Sambaiah, K ^a   Lokesh, B R ^a  

^a CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

6 OXOPROSTAGLANDIN F1 ALPHA; ARACHIDONIC ACID; ARACHIS OIL; CALCIUM IONOPHORE; LEUKOTRIENE; LEUKOTRIENE B4; LEUKOTRIENE C4; LEUKOTRIENE D4; MILK FAT; PROSTAGLANDIN; PROSTAGLANDIN E2; THROMBOXANE;

ANIMAL CELL; ARTICLE; CALORIC INTAKE; CELL SECRETION; CONTROLLED STUDY; MALE; NEWBORN; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; RAT;

EID: 0032747635     PISSN: 09523278     EISSN: None     Source Type: Journal    
DOI: 10.1054/plef.1999.0097     Document Type: Article

References (37)

1. Reiser R. Saturated fat in the diet and serum cholesterol concentration: a critical examination of literature. Am J Clin Nutr. 26:1973;525-555.
2. Grundy S. M., Denke M. A. Dietary influences on serum lipids and lipoproteins. J Lipid Res. 31:1990;1149-1172.
3. Mullane K. M., Pinto A. Endothelium arachidonic acid and coronary vascular tone. Fed Proc. 46:1987;2422-2433.
4. Marcus A. J. The eicosanoids in biology and medicine. J. Lipid Res. 25:1984;1511-1518.
5. Imir T., Sibitt W., Bankhurst A. A relative resistance of lymphokine activated killer cells to supression by prostaglandins and glucocorticoids. Prost Leukotrienes Med. 28:1987;111-118.
6. Vergroesen A. J. The Role of Fats in Human Nutrition. 1975;Academic Press, New York.
7. Kinsella J. E., Lokesh B. R., Broughton S., Whelan J. Dietary polyunsaturated fatty acids and eicosanoids: potential effects on the modulation of inflammatory and immune cells: an overview. Nutrition (supplement). 5:1989;24-44.
8. Burton J. L. Dietary fatty acids and inflammatory skin disease. Lancet. 1:1989;27-31.
9. Kumar M. V., Sambaiah K., Lokesh B. R. Effect of dietary ghee, the anhydrous milk fat on blood and liver lipids in rats. J Nutr Biochem. 10:1999;96-104.
10. Heyn B. The Gentle Strength of Indian Healing: in Ayurvedic Medicine. 1993;Harper Collins, New Delhi. p. 112-113.
11. 4. Lancet. ii:1982;762-763.
12. Turek J. J., Li Y., Schoenlein I. A., Allen K. G. D., Watkins B. A. Modulation of macrophage cytokine production by conjugated linoleic acids is influenced by the dietary n-6:n-3 fatty acid ratio. J Nutr Biochem. 9:1989;258-266.
13. Girsh, L. S. US patent, 1992, 5, 12 636.
14. Stine C. M., Harland H. A., Coulter S. T., Jenness R. A modified peroxide test for determination of lipid oxidation in dairy products. J Dairy Sci. 37:1954;202-208.
15. J Nutr. 107:1977;1340-1348.
16. Joe B., Lokesh B. R. Role of Capsaicin, Curcumin and dietary n-3 fatty acids in lowering the generation of reactive oxygen species in rat peritoneal macrophages. Biochim Biophys Acta. 1224:1994;255-263.
17. Lokesh B. R., Hseih H. L., Kinsella J. E. Alteration in the lipids and prostaglandins in mouse spleen following the ingestion of menhaden oil. Ann Nutr Metab. 30:1986;357-364.
18. Dutrieu J., Delmotte Y. A. Separation of prostaglandins by HPLC. Fresenius'Z Anal Chem. 315:1983;360.
19. 4on ionophore A23187 challenge. J Allergy Clin Immunol. 74:1984;310.
20. Abe M., Kawazue Y., Shigematsu N. Influence of salts on high performance of liquid chromatography of leukotrienes. Anal Biochem. 144:1985;417-422.
21. Bligh E. G., Dyer W. J. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 37:1959;911-917.
22. Morrison M. R., Smith M. Preparation of fatty acid methyl esters and dimethyl acetals from lipids with boron fluoride-ethanol. J Lipid Res. 5:1964;600-608.
23. Sedmak J. J., Grossberg E. A rapid sensitive and versatile assay for protein using coomassie brillant blue - G-250. Anal Biochem. 79:1977;544-552.
24. Snedecor G. W., Cochran W. G. Statistical methods. 1967;Iowa State University Press, Ames, IA.
25. Joe B., Lokesh B. R. Effect of curcumin and capsaicin on arachidonic acid metabolism and lysosomal enzyme secretion by rat peritoneal macrophages. Lipids. 32:1997;1173-1180.
26. Smith L. L. Review of progress in sterol oxidations: 1987-1995. Lipids. 31:1996;453-487.
27. Jacobson M. S. Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations. Lancet. ii:1987;656-658.
28. Leaf A., Weber P. C. Cardiovascular effects of n-3 fatty acids. N Engl J Med. 318:1988;549-556.
29. Kinsella J. E., Lokesh B., Stone R. A. Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: Possible mechanisms. Am J Clin Nutr. 52:1990;1-28.
30. O'Dea K., Steel M., Naughton J. Butter enriched diets reduce arterial prostacyclin production in rats. Lipids. 23:1988;234-241.
31. Mathias M. V., Dupont J. Quantitative relationships between dietary linoleic acid and prostaglandin biosynthesis. Lipids. 20:1985;791-801.
32. German B. J., Lokesh B., Kinsella J. E. Modulation of zymosan stimulated leukotriene release by dietary unsaturated fatty acids. Prost Leukotrienes Med. 30:1987;69-76.
33. Lefkowith J. B., Jakschik B. A., Stahl P., Needleman P. Metabolic and functional alterations in macrophages induced by essential fatty acid deficiency. J Biol Chem. 262:1987;6668-6675.
34. 4hydrolase. J Biol Chem. 260:1985;10966-10970.
35. 4and supress levels of resident and elicited leukocytes in acute inflammation. J Immunol. 140:1988;228-235.
36. Kumar M. V., Sambaiah K., Mangalgi S. G., Murthy N. A., Lokesh B. R. Effect of ghee on serum lipid levels in psoriasis patients. Ind J Dairy Biosci. 10:1999.
37. Holman R. T., Jhonson S. B., Mercurie O. M., Itarte H. J., Rodrigo M. A., De Tomas M. E. Essential fatty acid deficiency in malnourished children. Am J Clin Nutr. 34:1981;1534-1539.