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Volumn 58, Issue SUPPL. 1, 1999, Pages

The rationale for the current boom in anti-TNFα treatment. Is there an effective means to define therapeutic targets for drugs that provide all the benefits of anti-TNFα and minimise hazards?

Author keywords

[No Author keywords available]

Indexed keywords

BLOCKING AGENT; TUMOR NECROSIS FACTOR ALPHA;

EID: 0032747020     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (35)

References (27)
  • 1
    • 0019145051 scopus 로고
    • Human leukocyte interferon produced by E. coli is biologically active
    • Goeddel DV, Yelverton E, Ullrich A, et al. Human leukocyte Interferon produced by E. coli is biologically active. Nature 1980;287:411-16.
    • (1980) Nature , vol.287 , pp. 411-416
    • Goeddel, D.V.1    Yelverton, E.2    Ullrich, A.3
  • 2
    • 0021681058 scopus 로고
    • Human tumor necrosis factor: Precursor structure expression and homology to lymphotoxin
    • Pennica D, Nedwin GE, Hayflick JS, et al. Human tumor necrosis factor: precursor structure expression and homology to lymphotoxin. Nature 1984;312:724-9.
    • (1984) Nature , vol.312 , pp. 724-729
    • Pennica, D.1    Nedwin, G.E.2    Hayflick, J.S.3
  • 3
    • 0020699991 scopus 로고
    • Structure and expression of a cloned cDNA for human interleukin-2
    • Taniguchi T, Matsui H, Fujita T, et al. Structure and expression of a cloned cDNA for human interleukin-2. Nature 1983;302:305-10.
    • (1983) Nature , vol.302 , pp. 305-310
    • Taniguchi, T.1    Matsui, H.2    Fujita, T.3
  • 5
    • 0023773031 scopus 로고
    • Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: Prolonged production of IL-1α
    • Buchan G, Barrett K, Turner M, Chantry D, Maini RN, Feldmann M. Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1α. Clin Exp Immunol 1988;73:449-55.
    • (1988) Clin Exp Immunol , vol.73 , pp. 449-455
    • Buchan, G.1    Barrett, K.2    Turner, M.3    Chantry, D.4    Maini, R.N.5    Feldmann, M.6
  • 6
    • 0024314554 scopus 로고
    • Inhibitory effect of TNF α antibodies on synovial cell interleukin-1 production in rheumatoid arthritis
    • Brennan FM, Chantry D, Jackson A, Maini R, Feldmann M. Inhibitory effect of TNF α antibodies on synovial cell interleukin-1 production in rheumatoid arthritis. Lancet 1989;ii:244-7.
    • (1989) Lancet , vol.2 , pp. 244-247
    • Brennan, F.M.1    Chantry, D.2    Jackson, A.3    Maini, R.4    Feldmann, M.5
  • 7
    • 0025939257 scopus 로고
    • Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: Regulation by tumor necrosis factor-α
    • Haworth C, Brennan FM, Chantry D, Turner M, Maini RN, Feldmann M. Expression of granulocyte-macrophage colony-stimulating factor in rheumatoid arthritis: regulation by tumor necrosis factor-α. Eur J Immunol 1991;21: 2575-9.
    • (1991) Eur J Immunol , vol.21 , pp. 2575-2579
    • Haworth, C.1    Brennan, F.M.2    Chantry, D.3    Turner, M.4    Maini, R.N.5    Feldmann, M.6
  • 8
    • 0029617952 scopus 로고
    • Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti-TNFα antibody with the IL-1 receptor antagonist
    • Butler DM, Maini RN, Feldmann M, Brennan FM. Modulation of proinflammatory cytokine release in rheumatoid synovial membrane cell cultures. Comparison of monoclonal anti-TNFα antibody with the IL-1 receptor antagonist. Eur Cytokine Network 1995,6:225-30.
    • (1995) Eur Cytokine Network , vol.6 , pp. 225-230
    • Butler, D.M.1    Maini, R.N.2    Feldmann, M.3    Brennan, F.M.4
  • 9
    • 0023712236 scopus 로고
    • Detection of tumor necrosis factor a but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum
    • Saxne T, Palladino MA, Jr, Heinegard D, Talal N, Wollheim FA. Detection of tumor necrosis factor a but not tumor necrosis factor β in rheumatoid arthritis synovial fluid and serum. Arthritis Rheum 1988;31:1041-5.
    • (1988) Arthritis Rheum , vol.31 , pp. 1041-1045
    • Saxne, T.1    Palladino M.A., Jr.2    Heinegard, D.3    Talal, N.4    Wollheim, F.A.5
  • 10
    • 0345698849 scopus 로고
    • TNF-α and TNF receptor expression and regulation in rheumatoid arthritis
    • Balint G, Gomor B, Hodinka L, eds. Amsterdam: Elsevier Science Publishers
    • Brennan FM, Gibbons D, Cope AP, Reed B, Maini RN, Feldmann M. TNF-α and TNF receptor expression and regulation in rheumatoid arthritis. In: Balint G, Gomor B, Hodinka L, eds. Rheumatology, state of the art. Amsterdam: Elsevier Science Publishers, 1992:115-17.
    • (1992) Rheumatology, State of the Art , pp. 115-117
    • Brennan, F.M.1    Gibbons, D.2    Cope, A.P.3    Reed, B.4    Maini, R.N.5    Feldmann, M.6
  • 11
    • 0026091413 scopus 로고
    • Localization of tumor necrosis factor a in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis
    • Chu CQ, Field M, Feldmann M, Maini RN. Localization of tumor necrosis factor a in synovial tissues and at the cartilage-pannus junction in patients with rheumatoid arthritis. Arthritis Rheum 1991;34:1125-32.
    • (1991) Arthritis Rheum , vol.34 , pp. 1125-1132
    • Chu, C.Q.1    Field, M.2    Feldmann, M.3    Maini, R.N.4
  • 12
    • 0026656850 scopus 로고
    • Involvement of endogenous tumour necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice
    • Thorbecke GJ, Shah R, Leu CH, Kuruvilla AP, Hardison AM, Palladino MA. Involvement of endogenous tumour necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice. Proc Natl Acad Sci USA 1992;89:7375-9.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7375-7379
    • Thorbecke, G.J.1    Shah, R.2    Leu, C.H.3    Kuruvilla, A.P.4    Hardison, A.M.5    Palladino, M.A.6
  • 13
    • 0026644298 scopus 로고
    • Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis
    • Williams RO, Feldmann M, Maini RN. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc Nat Acad Sci USA 1992;89:9784-8.
    • (1992) Proc Nat Acad Sci USA , vol.89 , pp. 9784-9788
    • Williams, R.O.1    Feldmann, M.2    Maini, R.N.3
  • 14
    • 0026677361 scopus 로고
    • Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor
    • Piguet PF, Grau GE, Vesin C, Loetscher H, Gentz R, Lesslauer W. Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor. Immunology 1992;77:510-14.
    • (1992) Immunology , vol.77 , pp. 510-514
    • Piguet, P.F.1    Grau, G.E.2    Vesin, C.3    Loetscher, H.4    Gentz, R.5    Lesslauer, W.6
  • 15
    • 0027438710 scopus 로고
    • Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to TNFα
    • Elliott MJ, Maini RN, Fcldmann M, et al. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to TNFα. Arthritis Rheum 1993;36:1681-90.
    • (1993) Arthritis Rheum , vol.36 , pp. 1681-1690
    • Elliott, M.J.1    Maini, R.N.2    Fcldmann, M.3
  • 16
    • 0028143211 scopus 로고
    • Randomised double blind comparison of a chimaeric monoclonal antibody to tumour necrosis factor a (cA2) versus placebo in rheumatoid arthritis
    • Ellioti MJ, Maini RN, Feldmann M, et al. Randomised double blind comparison of a chimaeric monoclonal antibody to tumour necrosis factor a (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10.
    • (1994) Lancet , vol.344 , pp. 1105-1110
    • Ellioti, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 17
    • 0029044028 scopus 로고
    • The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CD571) in rheumatoid arthritis
    • Rankin ECC, Choy EHS, Kassimos D, et al. The therapeutic effects of an engineered human anti-tumour necrosis factor alpha antibody (CD571) in rheumatoid arthritis. Br J Rheumatol 1995;34:334-42.
    • (1995) Br J Rheumatol , vol.34 , pp. 334-342
    • Rankin, E.C.C.1    Choy, E.H.S.2    Kassimos, D.3
  • 18
    • 0013511183 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein
    • Moreland LW, Baumgartner SW, Schiff MH, et al. Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein. N Engl J Med 1997;337:141-7.
    • (1997) N Engl J Med , vol.337 , pp. 141-147
    • Moreland, L.W.1    Baumgartner, S.W.2    Schiff, M.H.3
  • 19
    • 0001668155 scopus 로고    scopus 로고
    • Loading/ maintenance doses approach to neutralization of TNF by Lenercept (TN-FR55-IgG1, Ro45-2081) inpatients with rheumatoid arthritis treated for 3 months: Results of a double-blind placebo controlled phase II trial
    • Cutolo M, Kirkham B, Bologna C, et al. Loading/ maintenance doses approach to neutralization of TNF by Lenercept (TN-FR55-IgG1, Ro45-2081) inpatients with rheumatoid arthritis treated for 3 months: results of a double-blind placebo controlled phase II trial. Arthritis Rheum 1996;39:S243.
    • (1996) Arthritis Rheum , vol.39
    • Cutolo, M.1    Kirkham, B.2    Bologna, C.3
  • 20
    • 0001782421 scopus 로고    scopus 로고
    • Efficacy and tolerability of weekly subcutaneous injections of the fully human anti THF antibody D2E7 in patients with rheumatoid arthritis - Results of a phase 1 study
    • Schattenkirchner M, Kruger K, Sander O, et al. Efficacy and tolerability of weekly subcutaneous injections of the fully human anti THF antibody D2E7 in patients with rheumatoid arthritis - Results of a phase 1 study. Arthritis Rheum 1998;41:S57.
    • (1998) Arthritis Rheum , vol.41
    • Schattenkirchner, M.1    Kruger, K.2    Sander, O.3
  • 21
    • 0345609037 scopus 로고    scopus 로고
    • Characterization of tumor necrosis factor-deficient mice
    • Marino MW, Dunn A, Grail D, et al. Characterization of tumor necrosis factor-deficient mice. Proc Natl Acad Sci USA 1997;94:8093-8.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8093-8098
    • Marino, M.W.1    Dunn, A.2    Grail, D.3
  • 22
    • 0032493278 scopus 로고    scopus 로고
    • Efficient adenoviral infection with TκBα reveals that TNFα production in rheumatoid arthritis is NF-κB dependent
    • Foxwell BMJ, Browne K, Bondeson J, et al. Efficient adenoviral infection with TκBα reveals that TNFα production in rheumatoid arthritis is NF-κB dependent. Proc Natl Acad Sci USA 1998;95:8211-15.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8211-8215
    • Foxwell, B.M.J.1    Browne, K.2    Bondeson, J.3
  • 23
    • 0033104615 scopus 로고    scopus 로고
    • Selective regulation of cytokine induction by adenoviral gene transfer of IκBα into human macrophages: LPS induced but not zymosan induced, pro-inflammatory cytokines are inhibited, but IL-10 is NFκb independent
    • Bondeson J, Brown KA, Brennan FM, Foxwell BMJ, Feldmann M. Selective regulation of cytokine induction by adenoviral gene transfer of IκBα into human macrophages: LPS induced but not zymosan induced, pro-inflammatory cytokines are inhibited, but IL-10 is NFκb independent. J Immunol 1999;162:2939-45.
    • (1999) J Immunol , vol.162 , pp. 2939-2945
    • Bondeson, J.1    Brown, K.A.2    Brennan, F.M.3    Foxwell, B.M.J.4    Feldmann, M.5
  • 24
    • 0029858387 scopus 로고    scopus 로고
    • TNF- and cancer therapy-induced apoptosis: Potentiation by inhibition of NF-κB
    • Wang C-Y, Mayo MW, Baldwin AS. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 1996;274:784-7.
    • (1996) Science , vol.274 , pp. 784-787
    • Wang, C.-Y.1    Mayo, M.W.2    Baldwin, A.S.3
  • 25
    • 0033545863 scopus 로고    scopus 로고
    • Defining therapeutic targets by using adenovirus: Blocking MF-κB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators
    • Bondeson J, Foxwell BMJ, Brennan FM, Feldmann M. Defining therapeutic targets by using adenovirus: blocking MF-κB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators. Proc Natl Acad Sci USA 1999;96:5668-73.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 5668-5673
    • Bondeson, J.1    Foxwell, B.M.J.2    Brennan, F.M.3    Feldmann, M.4
  • 26
    • 0003089209 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase gene expression
    • Parks WC, Mecham RP, eds. San Diego: Academic
    • Fini ME, Cook JR, Mohan R, Brinckerhoff CE. Regulation of matrix metalloproteinase gene expression. In: Parks WC, Mecham RP, eds, Matrix metalloproteinases. San Diego: Academic, 1998:299-356.
    • (1998) Matrix Metalloproteinases , pp. 299-356
    • Fini, M.E.1    Cook, J.R.2    Mohan, R.3    Brinckerhoff, C.E.4
  • 27
    • 0025313006 scopus 로고
    • A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins
    • Smith CA, Davis T, Anderson D, et al. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 1990;248:1019-23.
    • (1990) Science , vol.248 , pp. 1019-1023
    • Smith, C.A.1    Davis, T.2    Anderson, D.3


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