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Volumn 106, Issue 9-10, 1999, Pages 889-909

Effects of co-administration of anticonvulsant and putative anticonvulsive agents and sub-/suprathreshold doses of L-Dopa upon motor behaviour of MPTP-treated mice

Author keywords

Anticonvulsive agents; C57 BL 6 mice; Co administration; Dopamine; FCE 26743; L Deprenyl; L Dopa; Lamotrigine; Motor activity; MPTP; Parkinsonism; Phenytoin; Restoration; Subthreshold dose; Suprathreshold dose; Synergism

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANTICONVULSIVE AGENT; DOPAMINE; LAMOTRIGINE; LEVODOPA; PHENYTOIN; SELEGILINE;

EID: 0032744908     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020050209     Document Type: Article
Times cited : (16)

References (55)
  • 1
    • 0019819120 scopus 로고
    • Anti-Parkinsonian and anticonvulsant activity of some silyl substituted dopamine derivatives
    • Agarwal JC, Nath C, Gupta GP, Bhargava KP, Shanker K (1981) Anti-Parkinsonian and anticonvulsant activity of some silyl substituted dopamine derivatives. Pharmacol Res Comm 13; 937-947
    • (1981) Pharmacol Res Comm , vol.13 , pp. 937-947
    • Agarwal, J.C.1    Nath, C.2    Gupta, G.P.3    Bhargava, K.P.4    Shanker, K.5
  • 3
    • 0000377834 scopus 로고    scopus 로고
    • Dopaminergic-glutamatergic balance in the forebrain: Functional studies of movement disorders in rats and mice
    • Beninger RJ, Palomo T, Archer T (eds). Madrid University Press, Madrid
    • Archer T, Bassen M, Peters D, Luthman J, Fredriksson A (1996) Dopaminergic-glutamatergic balance in the forebrain: functional studies of movement disorders in rats and mice. In: Beninger RJ, Palomo T, Archer T (eds) Dopamine disease states. Madrid University Press, Madrid, pp 117-154
    • (1996) Dopamine Disease States , pp. 117-154
    • Archer, T.1    Bassen, M.2    Peters, D.3    Luthman, J.4    Fredriksson, A.5
  • 4
    • 0001686008 scopus 로고    scopus 로고
    • Effects of acute/chronic, subthreshold/threshold doses of L-Dopa in MPTP-treated mice. I. Influence of competitive and noncompetitive NMDA antagonists
    • Palomo T, Beninger RJ, Archer T (eds). Editorial Sintesis, Madrid
    • Archer T, Fredriksson A (1999) Effects of acute/chronic, subthreshold/threshold doses of L-Dopa in MPTP-treated mice. I. Influence of competitive and noncompetitive NMDA antagonists. In: Palomo T, Beninger RJ, Archer T (eds) Interactive monoaminergic disorders. Editorial Sintesis, Madrid, pp 573-606
    • (1999) Interactive Monoaminergic Disorders , pp. 573-606
    • Archer, T.1    Fredriksson, A.2
  • 5
    • 0009528790 scopus 로고
    • Characteristics of the inhibitory action of diphenylhydantoin on brain monoamine oxidase
    • Azzaro AJ, Gutrecht JA (1975) Characteristics of the inhibitory action of diphenylhydantoin on brain monoamine oxidase. Neurology 25: 378-383
    • (1975) Neurology , vol.25 , pp. 378-383
    • Azzaro, A.J.1    Gutrecht, J.A.2
  • 6
    • 0021332877 scopus 로고
    • Potentiation of the "dopa" effect in parkinsonism by a direct GABA receptor agonist
    • Bergmann KJ, Limongi JC, Lowe YH, Mendoza MR, Yahr MD (1984) Potentiation of the "dopa" effect in parkinsonism by a direct GABA receptor agonist [letter]. Lancet i: 559
    • (1984) Lancet , vol.1 , pp. 559
    • Bergmann, K.J.1    Limongi, J.C.2    Lowe, Y.H.3    Mendoza, M.R.4    Yahr, M.D.5
  • 7
    • 0025785785 scopus 로고
    • Pharmacology of the novel 5-hydroxytryptamine 1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: Inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects
    • Björk L, Cornfield LJ, Nelson DL, Hillver S-E, Andén N-E, Lewander T, Hacksell U (1991) Pharmacology of the novel 5-hydroxytryptamine 1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects. J Pharmacol Exp Ther 258: 58-65
    • (1991) J Pharmacol Exp Ther , vol.258 , pp. 58-65
    • Björk, L.1    Cornfield, L.J.2    Nelson, D.L.3    Hillver, S.-E.4    Andén, N.-E.5    Lewander, T.6    Hacksell, U.7
  • 8
    • 0026337914 scopus 로고
    • Chronic L-Dopa treatment in the unilateral 6-OHDA rat: Evidence for behavioural sensitization and biochemical tolerance
    • Carey RJ (1991) Chronic L-Dopa treatment in the unilateral 6-OHDA rat: evidence for behavioural sensitization and biochemical tolerance. Brain Res 568: 205-214
    • (1991) Brain Res , vol.568 , pp. 205-214
    • Carey, R.J.1
  • 9
    • 0009508583 scopus 로고
    • Effect of monoamine inhibitors on experimental convulsions
    • Chow ML, Hendley CD (1959) Effect of monoamine inhibitors on experimental convulsions. Fed Proc 18: 376
    • (1959) Fed Proc , vol.18 , pp. 376
    • Chow, M.L.1    Hendley, C.D.2
  • 11
  • 12
    • 4243427918 scopus 로고    scopus 로고
    • Monoamine interactions in animal models of epilepsy
    • Palomo T, Beninger RJ, Archer T (eds). Editorial Sintesis, Madrid
    • Ebert U, Löscher W (1999) Monoamine interactions in animal models of epilepsy. In: Palomo T, Beninger RJ, Archer T (eds) Interactive monoaminergic basis of brain disorders. Editorial Sintesis, Madrid, pp 555-572
    • (1999) Interactive Monoaminergic Basis of Brain Disorders , pp. 555-572
    • Ebert, U.1    Löscher, W.2
  • 13
    • 0028556522 scopus 로고
    • NMDA receptor blockade reverses motor response alterations induced by levodopa
    • Engber TM, Papa SM, Boldry RC, Chase TN (1994) NMDA receptor blockade reverses motor response alterations induced by levodopa. Neuroreport 5; 2586-2588
    • (1994) Neuroreport , vol.5 , pp. 2586-2588
    • Engber, T.M.1    Papa, S.M.2    Boldry, R.C.3    Chase, T.N.4
  • 14
    • 0028174377 scopus 로고
    • MPTP-induced behavioural and biochemical deficits: A paramatric analysis
    • Fredriksson A, Archer T (1994) MPTP-induced behavioural and biochemical deficits: a paramatric analysis. J Neural Transm 7: 123-132
    • (1994) J Neural Transm , vol.7 , pp. 123-132
    • Fredriksson, A.1    Archer, T.2
  • 15
    • 0029117493 scopus 로고
    • Synergistic interactions betseen COMT-/MAO-inhibitors and L-Dopa in MPTP-treated mice
    • Fredriksson A, Archer T (1995) Synergistic interactions betseen COMT-/MAO-inhibitors and L-Dopa in MPTP-treated mice. J Neural Transm 102: 19-34
    • (1995) J Neural Transm , vol.102 , pp. 19-34
    • Fredriksson, A.1    Archer, T.2
  • 17
    • 0028169412 scopus 로고
    • Synergistic interactions between NMDA-antagonists and L-Dopa on activity in MPTP-treated mice
    • Fredriksson A, Gentsch C, Archer T (1994a) Synergistic interactions between NMDA-antagonists and L-Dopa on activity in MPTP-treated mice. J Neural Transm [Gen Sect] 97: 197-209
    • (1994) J Neural Transm [Gen Sect] , vol.97 , pp. 197-209
    • Fredriksson, A.1    Gentsch, C.2    Archer, T.3
  • 18
    • 0028073324 scopus 로고
    • Effect of the competitive NMDA antagonist, CGP 40116, and a low dose of L-Dopa on the motor activity deficit of MPTP-treated mice
    • Fredriksson A, Gentsch C, Archer T (1994b) Effect of the competitive NMDA antagonist, CGP 40116, and a low dose of L-Dopa on the motor activity deficit of MPTP-treated mice. Behav Pharmacol 5: 599-606
    • (1994) Behav Pharmacol , vol.5 , pp. 599-606
    • Fredriksson, A.1    Gentsch, C.2    Archer, T.3
  • 19
    • 0030692667 scopus 로고    scopus 로고
    • MPTP-induced deficits in motor activity: Neuroprotective effects of the spintrapping agent, a-phenyl-tert-butyl-nitrone (PBN)
    • Fredriksson A, Eriksson P, Archer T (1997) MPTP-induced deficits in motor activity: neuroprotective effects of the spintrapping agent, a-phenyl-tert-butyl-nitrone (PBN). J Neural Transm 104: 579-592
    • (1997) J Neural Transm , vol.104 , pp. 579-592
    • Fredriksson, A.1    Eriksson, P.2    Archer, T.3
  • 20
    • 0032944412 scopus 로고    scopus 로고
    • Tolerance to a suprathreshold dose of L-Dopa in MPTP mice: Effects of glutamate antagonists
    • Fredriksson A, Palomo T, Chase T, Archer T (1999) Tolerance to a suprathreshold dose of L-Dopa in MPTP mice: effects of glutamate antagonists. J Neural Transm 106: 283-300
    • (1999) J Neural Transm , vol.106 , pp. 283-300
    • Fredriksson, A.1    Palomo, T.2    Chase, T.3    Archer, T.4
  • 21
    • 0027179598 scopus 로고
    • Lamotrigine: A review of its pharmacological properties and clinical efficacy in epilepsy
    • Goa KL, Ross SR, Chrisp P (1993) Lamotrigine: a review of its pharmacological properties and clinical efficacy in epilepsy. Drugs 46: 152-176
    • (1993) Drugs , vol.46 , pp. 152-176
    • Goa, K.L.1    Ross, S.R.2    Chrisp, P.3
  • 22
    • 0028232327 scopus 로고
    • Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease
    • Greenamyre JT, Eller RV, Zhang Z, Ovadia A, Kurlan R, Gash DM (1994) Antiparkinsonian effects of remacemide hydrochloride, a glutamate antagonist, in rodent and primate models of Parkinson's disease. Ann Neurol 35: 655-661
    • (1994) Ann Neurol , vol.35 , pp. 655-661
    • Greenamyre, J.T.1    Eller, R.V.2    Zhang, Z.3    Ovadia, A.4    Kurlan, R.5    Gash, D.M.6
  • 23
    • 0015262745 scopus 로고
    • Uptake and binding of catecholamines. Effect of diphenylhydantoin and a new mechanism of action
    • Hadfield MG (1972) Uptake and binding of catecholamines. Effect of diphenylhydantoin and a new mechanism of action. Arch Neurol 26: 78-83
    • (1972) Arch Neurol , vol.26 , pp. 78-83
    • Hadfield, M.G.1
  • 24
    • 0024381035 scopus 로고
    • Some features of the nigrostiatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine (MPTP) in the mouse
    • Heikkila RE, Sieber B-A, Manzino L, Sonsalla PK (1989) Some features of the nigrostiatal dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine (MPTP) in the mouse. Mol Chem Neuropathol 10: 171-183
    • (1989) Mol Chem Neuropathol , vol.10 , pp. 171-183
    • Heikkila, R.E.1    Sieber, B.-A.2    Manzino, L.3    Sonsalla, P.K.4
  • 25
    • 0028107371 scopus 로고
    • The novel anticonvulsant lamotrigine prevents dopamine depletion in C57 Black mice in the MPTP animal model of Parkinson's disease
    • Jones-Humble SA, Morgan PF, Cooper BR (1993) The novel anticonvulsant lamotrigine prevents dopamine depletion in C57 Black mice in the MPTP animal model of Parkinson's disease. Life Sci 54: 245-252
    • (1993) Life Sci , vol.54 , pp. 245-252
    • Jones-Humble, S.A.1    Morgan, P.F.2    Cooper, B.R.3
  • 26
    • 0030598616 scopus 로고    scopus 로고
    • Motor effects of lamotrigine in naive and dopamine-depleted mice
    • Kaur S, Starr M (1996) Motor effects of lamotrigine in naive and dopamine-depleted mice. Eur J Pharmacol 304: 1-6
    • (1996) Eur J Pharmacol , vol.304 , pp. 1-6
    • Kaur, S.1    Starr, M.2
  • 28
    • 0028146708 scopus 로고
    • Felbamate, ananti-convulsive drug, has anti-parkinsonian potential in rats
    • Kretschmer BD (1994) Felbamate, ananti-convulsive drug, has anti-parkinsonian potential in rats. Neurosci Lett 179: 115-118
    • (1994) Neurosci Lett , vol.179 , pp. 115-118
    • Kretschmer, B.D.1
  • 29
  • 30
    • 0021893793 scopus 로고
    • MPTP neurotoxicity: An overview and characterisation of phases of toxicity
    • Langston JW (1985) MPTP neurotoxicity: an overview and characterisation of phases of toxicity. Life Sci 36: 201-206
    • (1985) Life Sci , vol.36 , pp. 201-206
    • Langston, J.W.1
  • 31
    • 0021796957 scopus 로고
    • Influence of pharmacological manipulation of inhibitory and excitatory neurotransmitter systems on seizure behaviour in the mongolian gerbil
    • Löscher W (1985) Influence of pharmacological manipulation of inhibitory and excitatory neurotransmitter systems on seizure behaviour in the mongolian gerbil. J Pharmacol Exp Ther 233: 204-213
    • (1985) J Pharmacol Exp Ther , vol.233 , pp. 204-213
    • Löscher, W.1
  • 32
    • 0029070492 scopus 로고
    • Anticonvulsant and antieleptogenic effect of L-Deprenyl (Selegiline) in the kindling model of epilepsy
    • Löscher W, Honack D (1995) Anticonvulsant and antieleptogenic effect of L-Deprenyl (Selegiline) in the kindling model of epilepsy. J Pharmacol Exp Ther 274: 307-314
    • (1995) J Pharmacol Exp Ther , vol.274 , pp. 307-314
    • Löscher, W.1    Honack, D.2
  • 33
    • 0030432586 scopus 로고    scopus 로고
    • 1-Deprenyl (Selegiline) exerts anticonvulsant effects against different seizure types in mice
    • Löscher W, Lehmann H (1996) 1-Deprenyl (Selegiline) exerts anticonvulsant effects against different seizure types in mice. J Pharmacol Exp Ther 277: 1410-1417
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1410-1417
    • Löscher, W.1    Lehmann, H.2
  • 35
    • 0022483897 scopus 로고
    • Diphenylhydantoin and phenobarbital suppresses the dopaminergic neurotoxicity of MPTP in mice
    • Melamed E, Martinovits G, Pikarsky E, Rosenthal J, Uzzan A (1986) Diphenylhydantoin and phenobarbital suppresses the dopaminergic neurotoxicity of MPTP in mice. Eur J Pharmacol 128: 255-257
    • (1986) Eur J Pharmacol , vol.128 , pp. 255-257
    • Melamed, E.1    Martinovits, G.2    Pikarsky, E.3    Rosenthal, J.4    Uzzan, A.5
  • 36
    • 0028535070 scopus 로고
    • The role of glutamate in epilepsy and other CNS disorders
    • Meldrum BS (1994) The role of glutamate in epilepsy and other CNS disorders. Neurology 44: S14-S23
    • (1994) Neurology , vol.44
    • Meldrum, B.S.1
  • 37
    • 84944662266 scopus 로고
    • A new series of anticonvulsant drugs tested by experiments in animals
    • Merritt HH, Putnam TJ (1938) A new series of anticonvulsant drugs tested by experiments in animals. Arch Neurol Psychiat 39: 1003-1015
    • (1938) Arch Neurol Psychiat , vol.39 , pp. 1003-1015
    • Merritt, H.H.1    Putnam, T.J.2
  • 38
    • 0022891177 scopus 로고
    • Pharmacological studies on lamotrigine, a novel potential antiepileptic drug. 1. Anticonvulsant profile in mice and rats
    • Miller AA, Wheatley P, Sawyer DA, Baxter MG, Roth B (1986) Pharmacological studies on lamotrigine, a novel potential antiepileptic drug. 1. Anticonvulsant profile in mice and rats. Epilepsia 27: 483-489
    • (1986) Epilepsia , vol.27 , pp. 483-489
    • Miller, A.A.1    Wheatley, P.2    Sawyer, D.A.3    Baxter, M.G.4    Roth, B.5
  • 39
    • 0028182791 scopus 로고
    • Inhibition of monoamine oxidase by clorgyline analogues
    • O'Brien EM, Tipton KF, Meroni M, Dostert P (1994) Inhibition of monoamine oxidase by clorgyline analogues. J Neural Transm 41 [Suppl]: 295-305
    • (1994) J Neural Transm , vol.41 , Issue.SUPPL. , pp. 295-305
    • O'Brien, E.M.1    Tipton, K.F.2    Meroni, M.3    Dostert, P.4
  • 40
    • 0031048102 scopus 로고    scopus 로고
    • Gabapentin for parkinsonism: A double-blind, placebo-controlled, crossover trial
    • Olson WL, Gruenthal M, Mueller ME, Olson WH (1997) Gabapentin for parkinsonism: a double-blind, placebo-controlled, crossover trial. Am J Med 102: 60-66
    • (1997) Am J Med , vol.102 , pp. 60-66
    • Olson, W.L.1    Gruenthal, M.2    Mueller, M.E.3    Olson, W.H.4
  • 41
    • 0029549250 scopus 로고
    • Neuroprotective properties of the uncompetitive NMDA receptor antagonist remacemide hydrochloride
    • Palmer GC, Cregan EF, Borrelli AR, Willett F (1995) Neuroprotective properties of the uncompetitive NMDA receptor antagonist remacemide hydrochloride. Ann NY Acad Sci 765: 236-247
    • (1995) Ann NY Acad Sci , vol.765 , pp. 236-247
    • Palmer, G.C.1    Cregan, E.F.2    Borrelli, A.R.3    Willett, F.4
  • 42
    • 0009537322 scopus 로고
    • An anticonvulsant effect of monoamine oxidase inhibitors
    • Prockop DJ, Shore PA, Brodie BB (1959) An anticonvulsant effect of monoamine oxidase inhibitors. Experientia 15: 145-147
    • (1959) Experientia , vol.15 , pp. 145-147
    • Prockop, D.J.1    Shore, P.A.2    Brodie, B.B.3
  • 43
    • 0020598208 scopus 로고
    • A double-blind study comparing carbamazepine with phenytoin as initial seizure therapy in adults
    • Ramsay RE, Wilder BJ, Berger JR, Bruni J (1983) A double-blind study comparing carbamazepine with phenytoin as initial seizure therapy in adults. Neurology 33: 904-910
    • (1983) Neurology , vol.33 , pp. 904-910
    • Ramsay, R.E.1    Wilder, B.J.2    Berger, J.R.3    Bruni, J.4
  • 44
    • 0028008995 scopus 로고
    • Mechanism of action of anticonvulsant felbamate: Opposing effects on N-methyl-D-aspartate and γ-aminobutyric acid A receptors
    • Rho JM, Donevan SD, Rogawski MA (1994) Mechanism of action of anticonvulsant felbamate: opposing effects on N-methyl-D-aspartate and γ-aminobutyric acid A receptors. Ann Neurol 35: 229-234
    • (1994) Ann Neurol , vol.35 , pp. 229-234
    • Rho, J.M.1    Donevan, S.D.2    Rogawski, M.A.3
  • 45
    • 0023121771 scopus 로고
    • Behavioural and biochemical evidence for a different effect of repeated administration of L-Dopa and bromocriptine on denervated versus non-denervated striatal dopamine receptors
    • Rouillard C, Bédard P, Falardeau P, DiPaolo T (1987) Behavioural and biochemical evidence for a different effect of repeated administration of L-Dopa and bromocriptine on denervated versus non-denervated striatal dopamine receptors. Neuropharmacology 26: 187-193
    • (1987) Neuropharmacology , vol.26 , pp. 187-193
    • Rouillard, C.1    Bédard, P.2    Falardeau, P.3    DiPaolo, T.4
  • 46
    • 0027052341 scopus 로고
    • Sensitization, response fluctuation and long-term effect of SKF-82958 and bromocriptine in the hemi-parkinsonian rat
    • Silverman PB (1992) Sensitization, response fluctuation and long-term effect of SKF-82958 and bromocriptine in the hemi-parkinsonian rat. Eur J Pharmacol 229: 235-240
    • (1992) Eur J Pharmacol , vol.229 , pp. 235-240
    • Silverman, P.B.1
  • 47
  • 48
    • 0022480636 scopus 로고
    • The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice
    • Sonsalla PK, Heikkila RE (1986) The influence of dose and dosing interval on MPTP-induced dopaminergic neurotoxicity in mice. Eur J Pharmacol 129: 339-345
    • (1986) Eur J Pharmacol , vol.129 , pp. 339-345
    • Sonsalla, P.K.1    Heikkila, R.E.2
  • 49
    • 0028152976 scopus 로고
    • The anticonvulsant FCE 26743 is a selective and short-acting MAO-B inhibitor devoid of inducing properties towards cytochrome P450-dependent testosterone hydroxylation in mice and rats
    • Strolin Benedetti M, Marrari P, Colombo M, Castelli MG, Arand M, Oesch F, Dostert P (1994) The anticonvulsant FCE 26743 is a selective and short-acting MAO-B inhibitor devoid of inducing properties towards cytochrome P450-dependent testosterone hydroxylation in mice and rats. J Pharm Pharmacol 46: 814-819
    • (1994) J Pharm Pharmacol , vol.46 , pp. 814-819
    • Strolin Benedetti, M.1    Marrari, P.2    Colombo, M.3    Castelli, M.G.4    Arand, M.5    Oesch, F.6    Dostert, P.7
  • 50
    • 0025118725 scopus 로고
    • Chronic neurochemical and behavioural changes in MPTP-lesioned C57 BL/6 mice: A model for Parkinson's disease
    • Sundström E, Fredriksson A, Archer T (1990) Chronic neurochemical and behavioural changes in MPTP-lesioned C57 BL/6 mice: a model for Parkinson's disease. Brain Res 528: 181-188
    • (1990) Brain Res , vol.528 , pp. 181-188
    • Sundström, E.1    Fredriksson, A.2    Archer, T.3
  • 51
    • 0028089926 scopus 로고
    • Lamotrigine - A clinical overview
    • Wallace SJ (1994) Lamotrigine - a clinical overview. Seizure 3: 47-51
    • (1994) Seizure , vol.3 , pp. 47-51
    • Wallace, S.J.1
  • 52
    • 0024330782 scopus 로고
    • Dissociation between the biochemical and behavioural recovery in MPTP-treated mice
    • Weihmüller FB, Hadjiconstantinou M, Bruno JP (1989) Dissociation between the biochemical and behavioural recovery in MPTP-treated mice. Pharmacol Biochem Behav 34: 113-117
    • (1989) Pharmacol Biochem Behav , vol.34 , pp. 113-117
    • Weihmüller, F.B.1    Hadjiconstantinou, M.2    Bruno, J.P.3
  • 53
    • 0024535118 scopus 로고
    • Effects of lamotrigine on electrically induced after discharge in aneasthetised rat, dog and marmoset
    • Wheatley P, Miller AA (1989) Effects of lamotrigine on electrically induced after discharge in aneasthetised rat, dog and marmoset. Epilepsia 30: 34-40
    • (1989) Epilepsia , vol.30 , pp. 34-40
    • Wheatley, P.1    Miller, A.A.2
  • 54
    • 0029032127 scopus 로고
    • Derivatives of cis-2-amino-8-hydroxy-1-methyltetralin. Mixed 5-HT1A-receptor agonists and dopamine-D2-receptor antagonists
    • Ye Liu Y, Yu H, Mohell N, Nordvall G, Lewander T, Hacksell U (1995) Derivatives of cis-2-amino-8-hydroxy-1-methyltetralin. Mixed 5-HT1A-receptor agonists and dopamine-D2-receptor antagonists. J Med Chem 38: 150-160
    • (1995) J Med Chem , vol.38 , pp. 150-160
    • Ye Liu, Y.1    Yu, H.2    Mohell, N.3    Nordvall, G.4    Lewander, T.5    Hacksell, U.6
  • 55
    • 0027448382 scopus 로고
    • Lamotrigine - Antiparkinsonian activity by blockade of glutamate release?
    • Zipp F, Baas H, Fischer PA (1993) Lamotrigine - antiparkinsonian activity by blockade of glutamate release? J Neural Transm [P-D Sect] 5: 67-75
    • (1993) J Neural Transm [P-D Sect] , vol.5 , pp. 67-75
    • Zipp, F.1    Baas, H.2    Fischer, P.A.3


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