메뉴 건너뛰기




Volumn 67, Issue 6, 1999, Pages 737-741

Usefulness of a dopamine transporter PET ligand [18F]β-CFT in assessing disability in Parkinson's disease

Author keywords

Dopamine reuptake, Parkinson's disease; Dopamine transporter; Positron emission tomography

Indexed keywords

3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; ANTIPARKINSON AGENT; DOPAMINE; DOPAMINE TRANSPORTER; FLUORINE 18; LIGAND;

EID: 0032744340     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.67.6.737     Document Type: Article
Times cited : (85)

References (46)
  • 1
    • 0024395281 scopus 로고
    • Dementia in Parkinson's disease is related to neuronal loss in the medial substantia nigra
    • Rinne JO, Rummukainen J, Paljärvi L, et al. Dementia in Parkinson's disease is related to neuronal loss in the medial substantia nigra. Ann Neurol 1989;26:47-50.
    • (1989) Ann Neurol , vol.26 , pp. 47-50
    • Rinne, J.O.1    Rummukainen, J.2    Paljärvi, L.3
  • 2
    • 0024434128 scopus 로고
    • Midbrain dopaminergic cell loss in Parkinson's disease: Computer visualization
    • German DC, Manaye K, Smith WK, et al. Midbrain dopaminergic cell loss in Parkinson's disease: computer visualization. Ann Neurol 1989;26:507-14.
    • (1989) Ann Neurol , vol.26 , pp. 507-514
    • German, D.C.1    Manaye, K.2    Smith, W.K.3
  • 3
    • 0024835910 scopus 로고
    • Subdivisional involvement of nigrostriatal loop in idiopathic Parkinson's disease and striatonigral degeneration
    • Goto S, Hirano A, Matsumoto S. Subdivisional involvement of nigrostriatal loop in idiopathic Parkinson's disease and striatonigral degeneration. Ann Neurol 1989;26:766-70.
    • (1989) Ann Neurol , vol.26 , pp. 766-770
    • Goto, S.1    Hirano, A.2    Matsumoto, S.3
  • 4
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley J, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 1991;114:2283-301.
    • (1991) Brain , vol.114 , pp. 2283-2301
    • Fearnley, J.1    Lees, A.J.2
  • 5
    • 0026076047 scopus 로고
    • The neuropathologic basis of different clinical subgroups of Parkinson's disease
    • Paulus W, Jellinger K. The neuropathologic basis of different clinical subgroups of Parkinson's disease. J Neuropathol Exp Neurol 1991;50:743-55.
    • (1991) J Neuropathol Exp Neurol , vol.50 , pp. 743-755
    • Paulus, W.1    Jellinger, K.2
  • 6
    • 0021257759 scopus 로고
    • Central dopaminergic pathways in hemiparkinsonism examined by positron emission tomography
    • Garnett ES, Nahmias C, Firnau G. Central dopaminergic pathways in hemiparkinsonism examined by positron emission tomography. Can J Neurol Sci 1984;11:174-9.
    • (1984) Can J Neurol Sci , vol.11 , pp. 174-179
    • Garnett, E.S.1    Nahmias, C.2    Firnau, G.3
  • 7
    • 0022551086 scopus 로고
    • Brain dopamine metabolism in patients with Parkinson's disease measured with positron emission tomography
    • Leenders KL, Palmer AJ, Quinn N, et al. Brain dopamine metabolism in patients with Parkinson's disease measured with positron emission tomography. J Neurol Neurosurg Psychiatry 1986;49:853-60.
    • (1986) J Neurol Neurosurg Psychiatry , vol.49 , pp. 853-860
    • Leenders, K.L.1    Palmer, A.J.2    Quinn, N.3
  • 8
    • 0025065388 scopus 로고
    • Differing patterns of striatal [18F]fluorodopa uptake in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy
    • Brooks DJ, Ibanez V, Sawle GV, et al. Differing patterns of striatal [18F]fluorodopa uptake in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy. Ann Neurol 1990;28:547-55.
    • (1990) Ann Neurol , vol.28 , pp. 547-555
    • Brooks, D.J.1    Ibanez, V.2    Sawle, G.V.3
  • 9
    • 0027296568 scopus 로고
    • 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease
    • 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease. Ann Neurol 1993;43:423-31.
    • (1993) Ann Neurol , vol.43 , pp. 423-431
    • Frost, J.J.1    Rosier, A.J.2    Reich, S.G.3
  • 11
    • 0029094141 scopus 로고
    • Decreased single-photon emission computed tomographic [123I]-CIT striatal uptake correlates with symptom severity in Parkinson's disease
    • Seibyl JP, Marek KL, Quinlan D, et al. Decreased single-photon emission computed tomographic [123I]-CIT striatal uptake correlates with symptom severity in Parkinson's disease. Ann Neurol 1995;38:589-98.
    • (1995) Ann Neurol , vol.38 , pp. 589-598
    • Seibyl, J.P.1    Marek, K.L.2    Quinlan, D.3
  • 12
    • 85044014250 scopus 로고    scopus 로고
    • Measurement of the dopaminergic degeneration in Parkinson's disease with [123I]β-CIT and SPECT. Correlation with clinical findings and comparison with multiple system atrophy and progressive supranuclear palsy
    • Brucke T, Assenbaum S, Pirker W, et al. Measurement of the dopaminergic degeneration in Parkinson's disease with [123I]β-CIT and SPECT. Correlation with clinical findings and comparison with multiple system atrophy and progressive supranuclear palsy. J Neural Transm Suppl 1997;50:9-24.
    • (1997) J Neural Transm Suppl , vol.50 , pp. 9-24
    • Brucke, T.1    Assenbaum, S.2    Pirker, W.3
  • 13
    • 0002657598 scopus 로고
    • Striatal dopamine transporter in different disability stages of Parkinson's disease studied with [123I]β-CIT SPECT
    • Rinne JO, Kuikka JT, Bergström KA, et al. Striatal dopamine transporter in different disability stages of Parkinson's disease studied with [123I]β-CIT SPECT. Parkinsonism and Related Disorders 1995;1:47-51.
    • (1995) Parkinsonism and Related Disorders , vol.1 , pp. 47-51
    • Rinne, J.O.1    Kuikka, J.T.2    Bergström, K.A.3
  • 14
    • 0031426062 scopus 로고    scopus 로고
    • Striatal dopamine transporter in Parkinson's disease: A study with a new radioligand [123I]β-CIT-FP
    • Rinne JO, Kuikka JT, Bergström KA, et al. Striatal dopamine transporter in Parkinson's disease: a study with a new radioligand [123I]β-CIT-FP. Parkinsonism and related disorders 1997;3:77-81.
    • (1997) Parkinsonism and Related Disorders , vol.3 , pp. 77-81
    • Rinne, J.O.1    Kuikka, J.T.2    Bergström, K.A.3
  • 15
    • 0029658009 scopus 로고    scopus 로고
    • 18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: Biodistribution in rats
    • 18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: biodistribution in rats. Synapse 1996;23:321-7.
    • (1996) Synapse , vol.23 , pp. 321-327
    • Haaparanta, M.1    Bergman, J.2    Laakso, A.3
  • 16
    • 0031594290 scopus 로고    scopus 로고
    • 18F]β-CFT (18F)WIN 35,428, a radioligand to study dopamine transporter with PET: Characterization in human subjects
    • 18F]β-CFT ([18F)WIN 35,428), a radioligand to study dopamine transporter with PET: characterization in human subjects. Synapse 1998;28:244-50.
    • (1998) Synapse , vol.28 , pp. 244-250
    • Laakso, A.1    Bergman, J.2    Haaparanta, M.3
  • 17
    • 0032919523 scopus 로고    scopus 로고
    • 18F]β-CFT, is reduced in early Parkinson's disease
    • 18F]β-CFT, is reduced in early Parkinson's disease. Synapse 1999;31:119-124.
    • (1999) Synapse , vol.31 , pp. 119-124
    • Rinne, J.O.1    Bergman, J.2    Ruottinen, H.3
  • 18
    • 9544238113 scopus 로고    scopus 로고
    • Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease
    • Wilson JM, Levey AI, Rajput A, et al. Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease. Neurology 1996;47: 718-26.
    • (1996) Neurology , vol.47 , pp. 718-726
    • Wilson, J.M.1    Levey, A.I.2    Rajput, A.3
  • 19
    • 0026670104 scopus 로고
    • High potency cocaine analogs: Neurochemical, imaging and behavioural studies
    • Boja JW, Cline EJ, Carroll FI, et al. High potency cocaine analogs: neurochemical, imaging and behavioural studies. Ann NY Acad Sci 1992;654:282-91.
    • (1992) Ann NY Acad Sci , vol.654 , pp. 282-291
    • Boja, J.W.1    Cline, E.J.2    Carroll, F.I.3
  • 20
    • 0028987519 scopus 로고
    • [3H]WIN 35,428 binding in the caudate nucleus of the rabbit: Evidence for a single site on the dopamine transporter
    • Aloyo VJ, Ruffin JS, Pazdalski PS, et al. [3H]WIN 35,428 binding in the caudate nucleus of the rabbit: evidence for a single site on the dopamine transporter. J Pharmacol Exp Ther 1995;273:435-44.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 435-444
    • Aloyo, V.J.1    Ruffin, J.S.2    Pazdalski, P.S.3
  • 21
    • 0000224448 scopus 로고
    • Unified Parkinson's disease rating scale
    • Fahn S, Marsden CD, Goldstein M, et al, eds. Florham Park, NJ: Macmillan
    • Fahn S, Elton RL, and the members of the UPDRS Development Committee. Unified Parkinson's disease rating scale. In: Fahn S, Marsden CD, Goldstein M, et al, eds. Recent developments in Parkinson's disease. Vol II. Florham Park, NJ: Macmillan, 1987:153-63.
    • (1987) Recent Developments in Parkinson's Disease , vol.2 , pp. 153-163
    • Fahn, S.1    Elton, R.L.2
  • 22
    • 0030810879 scopus 로고    scopus 로고
    • Fluorine-18-labelled fluorine gas for synthesis of tracer molecules
    • Bergman J, Solin O. Fluorine-18-labelled fluorine gas for synthesis of tracer molecules. Nucl Med Biol 1997;24:677-83.
    • (1997) Nucl Med Biol , vol.24 , pp. 677-683
    • Bergman, J.1    Solin, O.2
  • 24
    • 0024592222 scopus 로고
    • Accurate three-dimensional registration of CT, PET and/or MR images of the brain
    • Pellizari CA, Chen GTY, Spelbring DR, et al. Accurate three-dimensional registration of CT, PET and/or MR images of the brain. J Comput Assist Tomogr 198913:20-6.
    • (1989) J Comput Assist Tomogr , vol.13 , pp. 20-26
    • Pellizari, C.A.1    Chen, G.T.Y.2    Spelbring, D.R.3
  • 25
    • 0027516578 scopus 로고
    • Functional imaging in relation to parkinsonian syndromes
    • Brooks DJ. Functional imaging in relation to parkinsonian syndromes. J Neurol Sci 1993:115:1-17.
    • (1993) J Neurol Sci , vol.115 , pp. 1-17
    • Brooks, D.J.1
  • 26
    • 0015262390 scopus 로고
    • Nigrostriatal and nigrothalamic fibers in the rhesus monkey
    • Carpenter MB, Peter P. Nigrostriatal and nigrothalamic fibers in the rhesus monkey. J Comp Neurol 1972;144:93-116.
    • (1972) J Comp Neurol , vol.144 , pp. 93-116
    • Carpenter, M.B.1    Peter, P.2
  • 27
    • 0018906646 scopus 로고
    • Organization of the ascending striatal afferents in monkeys
    • Szabo J. Organization of the ascending striatal afferents in monkeys. J Comp Neurol 1980;189:307-21.
    • (1980) J Comp Neurol , vol.189 , pp. 307-321
    • Szabo, J.1
  • 28
    • 0002724965 scopus 로고
    • Pathology of Parkinson's disease
    • DB Calne ed. Philadelphia: Saunders
    • Fearnley J, Lees AJ. Pathology of Parkinson's disease. In: DB Calne ed. Neurodegenerative diseases. Philadelphia: Saunders, 1994:545-54.
    • (1994) Neurodegenerative Diseases , pp. 545-554
    • Fearnley, J.1    Lees, A.J.2
  • 29
    • 0023874410 scopus 로고
    • Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease
    • Kish SJ, Shannak K, Hornykiewicz O. Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. N Engl J Med 1988;318:876.
    • (1988) N Engl J Med , vol.318 , pp. 876
    • Kish, S.J.1    Shannak, K.2    Hornykiewicz, O.3
  • 30
    • 0029664364 scopus 로고    scopus 로고
    • [123I]CIT/SPECT imaging demonstrates loss of dopamine transporters in hemi-Parkinson's disease
    • Marek KL, Seibyl JP, Zoghbi SS, et al. [123I]CIT/SPECT imaging demonstrates loss of dopamine transporters in hemi-Parkinson's disease. Neurology 1996;46:231-7.
    • (1996) Neurology , vol.46 , pp. 231-237
    • Marek, K.L.1    Seibyl, J.P.2    Zoghbi, S.S.3
  • 31
    • 1842290405 scopus 로고    scopus 로고
    • Which clinical signs of Parkinson's diseasee best reflect the nigrostriatal lesion?
    • Vingerhoets FJ, Schulzer M, Calne DB, et al. Which clinical signs of Parkinson's diseasee best reflect the nigrostriatal lesion? Ann Neurol 1997;41:58-64.
    • (1997) Ann Neurol , vol.41 , pp. 58-64
    • Vingerhoets, F.J.1    Schulzer, M.2    Calne, D.B.3
  • 32
    • 0025091036 scopus 로고
    • The metabolic anatomy of Parkinson's disease: Complementary [18F]fluorodeoxyg!ucose and [18F]fluorodopa positron emission tomographic studies
    • Eidelberg D, Moeller JR, Dhawan V, et al. The metabolic anatomy of Parkinson's disease: complementary [18F]fluorodeoxyg!ucose and [18F]fluorodopa positron emission tomographic studies. Mov Disord 1990;5:203-13.
    • (1990) Mov Disord , vol.5 , pp. 203-213
    • Eidelberg, D.1    Moeller, J.R.2    Dhawan, V.3
  • 33
    • 0025185168 scopus 로고
    • The relationship between locomotor disability, autonomic dysfunction and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomie failure and Parkinson's disease, studied with PET
    • Brooks DJ, Salmon EP, Mathias CJ, et al. The relationship between locomotor disability, autonomic dysfunction and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomie failure and Parkinson's disease, studied with PET. Brain 1990;113: 1539-52.
    • (1990) Brain , vol.113 , pp. 1539-1552
    • Brooks, D.J.1    Salmon, E.P.2    Mathias, C.J.3
  • 34
    • 0015576072 scopus 로고
    • Brain catecholamines and their metabolites in parkinsonian patients. Treatment with levodopa alone or combined with a decarboxylase inhibitor
    • Rinne UK, Sonninen V. Brain catecholamines and their metabolites in parkinsonian patients. Treatment with levodopa alone or combined with a decarboxylase inhibitor. Arch Neurol 1973;28:107-10.
    • (1973) Arch Neurol , vol.28 , pp. 107-110
    • Rinne, U.K.1    Sonninen, V.2
  • 35
    • 0015745743 scopus 로고
    • Brain dopamine and the syndromes of Parkinson and Huntington
    • Bernheimer H, Birkmeyer W, Hornykiewicz O, et al. Brain dopamine and the syndromes of Parkinson and Huntington. J Neurol Sci 1973;20:415-45.
    • (1973) J Neurol Sci , vol.20 , pp. 415-445
    • Bernheimer, H.1    Birkmeyer, W.2    Hornykiewicz, O.3
  • 37
    • 0027978063 scopus 로고
    • The behavioural and motor consequences of focal lesions of the basal ganglia in man
    • Bhatia KP, Marsden CD. The behavioural and motor consequences of focal lesions of the basal ganglia in man. Brain 1994;117:859-76.
    • (1994) Brain , vol.117 , pp. 859-876
    • Bhatia, K.P.1    Marsden, C.D.2
  • 38
    • 17144434961 scopus 로고
    • SPECT imaging of dopamine and serotonin transporters with [123I]CIT: Pharmacological characterization of brain uptake in nonhuman primates
    • Laruelle M, Baldwin R, Malison R, et al. SPECT imaging of dopamine and serotonin transporters with [123I]CIT: pharmacological characterization of brain uptake in nonhuman primates. Synapse 1993;13:295-309.
    • (1993) Synapse , vol.13 , pp. 295-309
    • Laruelle, M.1    Baldwin, R.2    Malison, R.3
  • 39
    • 0028176919 scopus 로고
    • Effect of l-deprenyl, its structural analogues and some monoamine oxidase inhibitors on dopamine uptake
    • Fang J, Yu P. Effect of l-deprenyl, its structural analogues and some monoamine oxidase inhibitors on dopamine uptake. Neuropharmacology 1994;33:763-8.
    • (1994) Neuropharmacology , vol.33 , pp. 763-768
    • Fang, J.1    Yu, P.2
  • 40
    • 0022495911 scopus 로고
    • The effect of repeated doses of (-)deprenyl on the dynamics of monoaminergic transmission. Comparison with clorgyline
    • Zilla G, Földi P, Held G, et al. The effect of repeated doses of (-)deprenyl on the dynamics of monoaminergic transmission. Comparison with clorgyline. Polish Journal of Pharmacology and Pharmacy 1986;38:57-67.
    • (1986) Polish Journal of Pharmacology and Pharmacy , vol.38 , pp. 57-67
    • Zilla, G.1    Földi, P.2    Held, G.3
  • 41
    • 0027981209 scopus 로고
    • Slow recovery of human brain MAO B after 1-deprenyl (selegiline) withdrawal
    • Fowler JS, Volkow ND, Logan J, et al. Slow recovery of human brain MAO B after 1-deprenyl (selegiline) withdrawal. Synapse 1994;18:86-93.
    • (1994) Synapse , vol.18 , pp. 86-93
    • Fowler, J.S.1    Volkow, N.D.2    Logan, J.3
  • 42
    • 0031684335 scopus 로고    scopus 로고
    • Iodine-123-β-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients
    • Seibyl JP, Marek K, Sheff K, et al. Iodine-123-β-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients. J Nucl Med 1998;39:1500-8.
    • (1998) J Nucl Med , vol.39 , pp. 1500-1508
    • Seibyl, J.P.1    Marek, K.2    Sheff, K.3
  • 43
    • 0030614902 scopus 로고    scopus 로고
    • [123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease
    • Booij J, Tissingh G, Boer GJ, et al. [123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease. J Neurol Neurosurg Psychiatry 1997;62:133-40.
    • (1997) J Neurol Neurosurg Psychiatry , vol.62 , pp. 133-140
    • Booij, J.1    Tissingh, G.2    Boer, G.J.3
  • 44
    • 0030610740 scopus 로고    scopus 로고
    • [11C]RTI-32 PET studies of the dopamine transporter in early dopa-naive Parkinson's disease: Implications for the symptomatic threshold
    • Guttman M, Burkholder J, Kish SJ, et al. [11C]RTI-32 PET studies of the dopamine transporter in early dopa-naive Parkinson's disease: implications for the symptomatic threshold. Neurology 1997;48:1578-83.
    • (1997) Neurology , vol.48 , pp. 1578-1583
    • Guttman, M.1    Burkholder, J.2    Kish, S.J.3
  • 45
    • 0023936741 scopus 로고
    • 11C-nomifensine and positron emission tomography: The effects of age and Parkinson's disease
    • 11C-nomifensine and positron emission tomography: the effects of age and Parkinson's disease. Acta Neurol Scand 1988;77:192-201.
    • (1988) Acta Neurol Scand , vol.77 , pp. 192-201
    • Tedroff, J.1    Aquilonius, S.-M.2    Hartvig, P.3
  • 46
    • 0025695511 scopus 로고
    • The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease
    • Leenders KL, Salmon EP, Tyrell P, et al. The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease. Arch Neurol 1990;47:1290-8.
    • (1990) Arch Neurol , vol.47 , pp. 1290-1298
    • Leenders, K.L.1    Salmon, E.P.2    Tyrell, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.