Relative expression of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 in mouse renal cell carcinoma cells regulates their metastatic potential

Clinical Cancer Research

Volumn 5, Issue 10, 1999, Pages 2824-2829

  Miyake, Hideaki ^a,c   Hara, Isao ^a   Gohji, Kazuo ^a   Yamanaka, Kazuki ^a   Hara, Shoji ^a   Arakawa, Soichi ^a   Nakajima, Motowo ^b   Kamidono, Sadao ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NOVARTIS PHARMA K K   (Japan)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CELL ADHESION; CELL INVASION; GENETIC TRANSFECTION; KIDNEY CARCINOMA; METASTASIS; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CARCINOMA, RENAL CELL; FEMALE; KIDNEY NEOPLASMS; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; RNA, MESSENGER; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TUMOR CELLS, CULTURED;

EID: 0032740803     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Fidler, I. J. Critical factors in the biology of human cancer metastasis: twenty-eighth G. H. A. Clowes Memorial Award Lecture. Cancer Res., 50: 6130-6138, 1990.
2. Aznavoorian, S., Murphy, A. N., Stetler-Stevenson, W. G., and Liotta, L. Molecular aspects of tumor cell invasion and metastasis. Cancer (Phila.), 71: 1368-1383, 1993.
3. Matrisian, L. M. The matrix-degrading metalloproteinases. BioEssays, 14: 455-463, 1992.
4. Stetler-Stevenson, W. G. Type-IV collagenases in tumor invasion and metastasis. Cancer Metastasis Rev., 9: 289-303, 1990.
5. Tryggvason, K. Type-IV collagenase in invasive tumors. Breast Cancer Res. Treat., 24: 209-218, 1993.
6. Declerck, Y. A., Perez, N., Shimada, H., Boone, T. C., Langley, K. E., and Taylor, S. M. Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. Cancer Res., 52: 701-708, 1992.
7. Montgomery, A. M. P., Muller, B. M., Reisfeld, R. A., Taylor, S. M., and Declerck, Y. A. Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line. Cancer Res., 54: 5467-5473, 1994.
8. Holland, J. M., Cancer of the kidney-natural history and staging. Cancer (Phila.), 32: 1030-1042, 1973.
9. Kugler, A., Hemmerlein, B., Thelen, P., Kallerhoff, M., Radzun, H. J., and Ringert, R. H. Expression of metalloproteinase 2 and 9 and their inhibitors in renal cell carcinoma. J. Urol., 160: 1914-1918, 1998.
10. Walther, M. M., Kleiner, D. E., Lubensky, I. A., Pozzatti, R., Nyguen, T., Gnarra, J. R., Hurley, K., Venzon, D., Linehan, W. M., and Stetler-Stevenson, W. G. Progelatinase. A mRNA expression in cell lines derived from tumors in patients with metastatic renal cell carcinoma correlates inversely with survival. Urology, 50: 295-301, 1997.
11. Miyake, H., Hara, I., Yoshimura, K., Eto, H., Arakawa, S., Wada, S., Chihara, K., and Kamidono, S. Introduction of basic fibroblast growth factor gene into mouse renal cell carcinoma cell line enhances its metastatic potential. Cancer Res., 56: 2440-2445, 1996.
12. Miyake, H., Hanada, N., Nakamura, H., Kagawa, S., Fujiwara, T., Hara, I., Eto, H., Gohji, K., Arakawa, S., Kamidono, S., and Saya, H. Overexpression of Bcl-2 in bladder cancer cells inhibits apoptosis induced by cisplatin and adenoviral-mediated p53 gene transfer. Oncogene, 16: 933-943, 1998.
13. Gleave, M. E., Hsieh, J. T., Gao, C., von Eschenbach, A. C., and Chung, L. W. K. Acceleration of human prostate carcinoma growth in vivo by factors produced by prostate and bone fibroblast. Cancer Res., 51: 3753-3761, 1991.
14. Miyake, H., Hara, I., Okamoto, I., Gohji, K., Yamanaka, K., Arakawa, S., Saya, H., and Kamidono, S. Interaction between CD44 and hyaluronic acid regulates human prostate cancer development. J. Urol., 160: 1562-1566, 1998.
15. Nuovo, G. J., Macconnell, P. B., Simsir, A., Valea, F., and French, D. L. Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma. Cancer Res., 55: 267-272, 1995.
16. Gohji, K., Fujimoto, N., Fujii, A., Komiyama, T., Okawa, J., and Nakajima, M. Prognostic significance of circulating matrix metalloproteinase-2 to tissue inhibitor of metalloproteinase-2 ratio in recurrence of urothelial cancer after complete resection. Cancer Res., 56: 3196-3198, 1996.
17. 3 integrin antibody induces the activated form of matrix metalloproteinase-2 (MMP-2) with concomitant stimulation of invasion through Matrigel by human rhabdomyosarcoma cells. Int. J. Cancer, 70: 106-111, 1997.
18. vβ3. Cell, 85: 683-693, 1996.
19. Koop, S., Khokha, R., Schmidt, E. E., MacDonald, I. C., Morris, V. L., Chambers, A. F., and Groom, A. C. Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth. Cancer Res., 54: 4791-4797, 1994.
20. Valente, P., Fassina, G., Melchiori, A., Masiello, L., Cilli, M., Vacca, A., Onisto, M., Santi, L., Stetler-Stevenson, W. G., and Albini, A. TIMP-2 over-expression reduces invasion and angiogenesis and protects B16F10 melanoma cells from apoptosis. Int. J. Cancer, 75: 246-253, 1998.
21. Kawamata, H., Kawai, K., Kameyama, S., Johnson, M. D., Stetler-Stevenson, W. G., and Oyasu, R. Over-expression of tissue inhibitor of matrix metalloproteinases (TIMP1 and TIMP2) suppresses extravasation of pulmonary metastasis of a rat bladder carcinoma. Int. J. Cancer, 63: 680-687, 1995.