Reciprocal modulation of glutamate and GABA release may underlie the anticonvulsant effect of phenytoin

Neuroscience

Volumn 95, Issue 2, 1999, Pages 343-351

  Cunningham, M O ^a   Dhillon, A ^a   Wood, S J ^a   Jones, R S G ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Entorhinal cortex; GABA release; Glutamate release; Phenytoin

Indexed keywords

4 AMINOBUTYRIC ACID; GLUTAMIC ACID; PHENYTOIN;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENTORHINAL CORTEX; EXCITATORY POSTSYNAPTIC POTENTIAL; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROBABILITY; RAT; SYNAPTIC MEMBRANE;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; ANTICONVULSANTS; BRAIN CHEMISTRY; ENTORHINAL CORTEX; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; MALE; NEURAL INHIBITION; PATCH-CLAMP TECHNIQUES; PHENYTOIN; PHOSPHINIC ACIDS; PROPANOLAMINES; RATS; RATS, WISTAR; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 0032740344     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00468-6     Document Type: Article

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