The effects of a newly synthesized ATP-Sensitive potassium channel opener, MJ-355, on blood pressure and myocardial ischemia-reperfusion injury in rats

Japanese Journal of Pharmacology

Volumn 81, Issue 2, 1999, Pages 185-193

  Lee, Yen Mei ^a   Peng, Yen Yen ^a   Sheu, Jeon Rong ^b   Cheng, Chen Yu ^c   Yen, Mao Hsiung ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Arrhythmias; Hypertension; K(ATP) channel; Myocardial ischemia; Reperfusion

Indexed keywords

6 CYANO 4 [2 (1 ETHOXYETHOXYMETHYL) 5 OXO 1 PYRROLIDINYL] 3,4 DIHYDRO 2,2 DIMETHYL 2H 1 BENZOPYRAN 3 OL; CROMAKALIM; GLIBENCLAMIDE; POTASSIUM CHANNEL STIMULATING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; DISEASE SEVERITY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG STRUCTURE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART RATE; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; INTRAVENOUS DRUG ADMINISTRATION; LEFT CORONARY ARTERY; MALE; MEAN ARTERIAL PRESSURE; MORTALITY; NONHUMAN; RAT; REPERFUSION INJURY; SPONTANEOUSLY HYPERTENSIVE RAT;

ANESTHESIA; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ANTIHYPERTENSIVE AGENTS; ARRHYTHMIA; ATP-BINDING CASSETTE TRANSPORTERS; BENZOPYRANS; BLOOD PRESSURE; CROMAKALIM; GLYBURIDE; HEMODYNAMIC PROCESSES; HYPERTENSION; HYPOGLYCEMIC AGENTS; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PYRROLIDINONES; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY;

EID: 0032739398     PISSN: 00215198     EISSN: None     Source Type: Journal    
DOI: 10.1254/jjp.81.185     Document Type: Article

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