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Volumn 57, Issue 6, 1998, Pages 314-322

Pharmacological characteristics of MJ-451, a new benzopyran-derived ATP-sensitive potassium channel opener, in guinea pig isolated trachea

Author keywords

Cromakalim; MJ 451; Trachea, guinea pig

Indexed keywords

6 CYANO 3,4 DIHYDRO 2,2 DIMETHYL 2H 3 HYDROXY 4 [2 OXO 1 HYDROXYMETHYL 1 PYRROLIDINYL] 1 BENZOPYRAN; 8 (4 SULFOPHENYL)THEOPHYLLINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); BENZOPYRAN DERIVATIVE; CARBACHOL; CHARYBDOTOXIN; CROMAKALIM; GLIBENCLAMIDE; HISTAMINE; ISOPRENALINE; POTASSIUM CHANNEL STIMULATING AGENT; POTASSIUM CHLORIDE; PROPRANOLOL; THEOPHYLLINE; UNCLASSIFIED DRUG;

EID: 0031771038     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000028257     Document Type: Article
Times cited : (2)

References (25)
  • 1
    • 0027409532 scopus 로고
    • The pharmacology of ATP-sensitive potassium channels
    • Edwards G, Weston AH: The pharmacology of ATP-sensitive potassium channels. Annu Rev Pharmacol Toxicol 1993;33:587-637.
    • (1993) Annu Rev Pharmacol Toxicol , vol.33 , pp. 587-637
    • Edwards, G.1    Weston, A.H.2
  • 4
    • 0024330439 scopus 로고
    • A comparison of the relaxant effects of pinacidil in guinea pig trachea, aorta, and pulmonary artery
    • Mellemkjær S, Nielsen-Kudsk JE, Nielsen CB, Siggaard C: A comparison of the relaxant effects of pinacidil in guinea pig trachea, aorta, and pulmonary artery. Eur J Pharmacol 1989;167:275-280.
    • (1989) Eur J Pharmacol , vol.167 , pp. 275-280
    • Mellemkjær, S.1    Nielsen-Kudsk, J.E.2    Nielsen, C.B.3    Siggaard, C.4
  • 5
    • 0024556728 scopus 로고
    • Short-term monotherapy with the potassium channel activator BRL-34915 on endocrine sodium regulation in essential hypertension
    • Lebel M, Grose JH, Lacouriere Y: Short-term monotherapy with the potassium channel activator BRL-34915 on endocrine sodium regulation in essential hypertension. Am J Hypertens 1989;2:256-258.
    • (1989) Am J Hypertens , vol.2 , pp. 256-258
    • Lebel, M.1    Grose, J.H.2    Lacouriere, Y.3
  • 6
    • 0023756903 scopus 로고
    • Evaluation of the potassium channel activator cromakalim (BRL 34915) as a bronchodilator in the guinea pig: Comparison with nifedipine
    • Arch JR, Buckle DR, Bumstead J, Clarke GD, Taylor JF, Taylor SG: Evaluation of the potassium channel activator cromakalim (BRL 34915) as a bronchodilator in the guinea pig: Comparison with nifedipine. Br J Pharmacol 1988;95:763-770.
    • (1988) Br J Pharmacol , vol.95 , pp. 763-770
    • Arch, J.R.1    Buckle, D.R.2    Bumstead, J.3    Clarke, G.D.4    Taylor, J.F.5    Taylor, S.G.6
  • 7
    • 0024520586 scopus 로고
    • The effects of cromakalim on the detrussor muscle of human and pig urinary bladder
    • Foster CD, Speakman MJ, Fujii K, Brading AF: The effects of cromakalim on the detrussor muscle of human and pig urinary bladder. Br J Urol 1989;63:284-294.
    • (1989) Br J Urol , vol.63 , pp. 284-294
    • Foster, C.D.1    Speakman, M.J.2    Fujii, K.3    Brading, A.F.4
  • 8
    • 0024318158 scopus 로고
    • Enhancement of potassium-sensitive current in heart cells by pinacidil. Evidence for modulation of the ATP-sensitive potassium channel
    • Arena JP, Kass RS: Enhancement of potassium-sensitive current in heart cells by pinacidil. Evidence for modulation of the ATP-sensitive potassium channel. Circ Res 1989;65: 436-443.
    • (1989) Circ Res , vol.65 , pp. 436-443
    • Arena, J.P.1    Kass, R.S.2
  • 9
    • 0025696538 scopus 로고
    • Pharmacological profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dog
    • Grover GJ, Sleph PG, Dzwonczy S: Pharmacological profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dog. J Cardiovasc Pharmacol 1995;16:853-864.
    • (1995) J Cardiovasc Pharmacol , vol.16 , pp. 853-864
    • Grover, G.J.1    Sleph, P.G.2    Dzwonczy, S.3
  • 10
    • 0028104008 scopus 로고
    • Pharmacological characteristics of liriodenine, isolated from Fissistigma glaucescens, a novel muscarinic receptor antagonist in guinea pig
    • Lin CH, Chang GJ, Su MJ, Wu YC, Teng CM, Ko FN: Pharmacological characteristics of liriodenine, isolated from Fissistigma glaucescens, a novel muscarinic receptor antagonist in guinea pig. Br J Pharmacol 1994;113:275-281.
    • (1994) Br J Pharmacol , vol.113 , pp. 275-281
    • Lin, C.H.1    Chang, G.J.2    Su, M.J.3    Wu, Y.C.4    Teng, C.M.5    Ko, F.N.6
  • 12
    • 0017902250 scopus 로고
    • How should values of pA2 and affinity constants for pharmacological competitive antagonists be estimated?
    • MacKay D: How should values of pA2 and affinity constants for pharmacological competitive antagonists be estimated? J Pharm Pharmacol 1978;30:312-313.
    • (1978) J Pharm Pharmacol , vol.30 , pp. 312-313
    • MacKay, D.1
  • 13
    • 0021686734 scopus 로고
    • Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle
    • Gustaffson LE: Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle. Acta Physiol Scand 1984;122:191-198.
    • (1984) Acta Physiol Scand , vol.122 , pp. 191-198
    • Gustaffson, L.E.1
  • 14
    • 0023243805 scopus 로고
    • Apparent affinity of some 8-phenyl-substituted xanthines at adenosine receptors in guinea pig aorta and atria
    • Collis MG, Jacobson KA, Tomkins DM: Apparent affinity of some 8-phenyl-substituted xanthines at adenosine receptors in guinea pig aorta and atria. Br J Pharmacol 1987;92:69-75.
    • (1987) Br J Pharmacol , vol.92 , pp. 69-75
    • Collis, M.G.1    Jacobson, K.A.2    Tomkins, D.M.3
  • 15
    • 0022542171 scopus 로고
    • Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein
    • Hamilton TC, Weir SW, Weston AH: Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein. Br J Pharmacol 1986; 88:103-111.
    • (1986) Br J Pharmacol , vol.88 , pp. 103-111
    • Hamilton, T.C.1    Weir, S.W.2    Weston, A.H.3
  • 16
    • 0024534172 scopus 로고
    • Cromakalim, nicorandil and pinacidil: New drugs which open potassium channels in smooth muscle
    • Hamilton TC, Weston AH: Cromakalim, nicorandil and pinacidil: New drugs which open potassium channels in smooth muscle. Gen Pharmacol 1989;20:1-9.
    • (1989) Gen Pharmacol , vol.20 , pp. 1-9
    • Hamilton, T.C.1    Weston, A.H.2
  • 17
    • 0025299550 scopus 로고
    • Potassium channel modulators: Scientific applications and therapeutic promise
    • Robertson DW, Steinberg MI: Potassium channel modulators: Scientific applications and therapeutic promise. J Med Chem 1990;33: 1529-1541.
    • (1990) J Med Chem , vol.33 , pp. 1529-1541
    • Robertson, D.W.1    Steinberg, M.I.2
  • 18
    • 0023262381 scopus 로고
    • Effects of phosphodiesterase inhibitors on normal and chemically-skinned isolated airway smooth muscle
    • Bryson SE, Rodger IW: Effects of phosphodiesterase inhibitors on normal and chemically-skinned isolated airway smooth muscle. Br J Pharmacol 1987;92:673-681.
    • (1987) Br J Pharmacol , vol.92 , pp. 673-681
    • Bryson, S.E.1    Rodger, I.W.2
  • 20


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.