Proliferation marker Ki-S11 - A prognostic indicator for squamous cell carcinoma of the hypopharynx

Virchows Archiv

Volumn 435, Issue 6, 1999, Pages 590-595

  Kuropkat, Christiane ^a   Rudolph, Pierre ^b   Frahm, Sven Olaf ^b   Parwaresch, Reza ^b   Werner, Jochen A ^c  

^a RUSH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF KIEL   (Germany)

^c NONE

Author keywords

Hypopharynx carcinoma; Immunohistochemistry; Ki S11; Prognosis; Proliferation

Indexed keywords

CELL MARKER; KI 67 ANTIGEN; MONOCLONAL ANTIBODY; PARAFFIN;

ADULT; AGED; ARTICLE; CANCER STATISTICS; CELL PROLIFERATION; CERVICAL LYMPH NODE; CONTROLLED STUDY; FOLLOW UP; HUMAN; HUMAN TISSUE; HYPOPHARYNX CARCINOMA; IMMUNOHISTOCHEMISTRY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TUMOR DIFFERENTIATION;

EID: 0032738501     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050445     Document Type: Article

References (49)

1. 1. Alvi A, Johnson JT (1996) Extracapsular spread in the clinically negative neck (N0): implications and outcome. Otolaryngol Head Neck Surg 114:65-70
2. 2. Bacchi CE, Gown AM (1993) Detection of cell proliferation in tissue sections. Braz J Med Biol Res 26:677-687
3. 3. Benazzo M, Mevio E, Occhini A, Franchini G, Danova M (1995) Proliferative characteristics of head and neck tumors. In vivo evaluation by bromodeoxyuridine incorporation and flow cytometry. ORL J Otorhinolaryngol Relat Spec 57:39-43
4. 4. Boysen M, Loven JO (1993) Second malignant neoplasms in patients with head and neck squamous cell carcinomas. Acta Oncol 32:283-288
5. 5. Brown DC, Gatter KC (1990) Monoclonal antibody Ki-67: its use in histopathology. Histopathology 17:489-503
6. 6. Cappiello J, Nicolai P, Antonelli AR, Facchetti F, Cadei M, Cornacchiari A, Grigolato PG (1995) DNA index, cellular proliferative activity and nucleolar organizer regions in cancers of the larynx. Eur Arch Otorhinolaryngol 252:353-358
7. 7. Cattoretti G, Becker MH, Key G, Duchrow M, Schluter C, Galle J, Gerdes J (1992) Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 168:357-363
8. 8. Corvo R, Giaretti W, Sanguineti G, Geido E, Orecchia R, Barra S, Margarino G, Bacigalupo A, Vitale V (1993) Potential doubling time in head and neck tumors treated by primary radiotherapy: preliminary evidence for a prognostic significance in local control. Int J Radiat Oncol Biol Phys 27: 1165-1172
9. 9. Dreyfuss AI, Clark JR (1991) Analysis of prognostic factors in squamous cell carcinomas of the head and neck. Hematol Oncol Clin North Am 5:701-712
10. 10. Edstrom SS, Gustafsson B, Stenman G, Lyden E, Stein H, Westin T (1991) Proliferative pattern of head and neck cancer. Am J Surg 162:412-416
11. 11. Erber R, Klein W, Andl T, Enders C, Born AI, Conradt C, Bartek J, Bosch FX (1997) Aberrant p21(CIP1/WAF1) protein accumulation in head-and-neck cancer. Int J Cancer 74:383-389
12. 12. Esser D, Meyer W, Willgeroth C, Motsch C (1994) Determination of prognosis-relevant factors in patients with hypo-or oropharyngeal carcinoma (in German). HNO 42:413-417
13. 13. Fenoglio Preiser CM (1992) Selection of appropriate cellular and molecular biologic diagnostic tests in the evaluation of cancer. Cancer 69:1607-1632
14. 14. Gatter KC, Dunnill MS, Gerdes J, Stein H, Mason DY (1986) New approach to assessing lung tumours in man. J Clin Pathol 39:590-593
15. 15. Gerdes J, Li L, Schluter C, Duchrow M, Wohlenberg C, Gerlach C, Stahmer I, Kloth S, Brandt E, Flad H-D (1991) Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol 138:867-873
16. 16. Grau JJ, Cuchi A, Traserra J, Firvida JL, Arias C, Blanch JL, Estape J (1997) Follow-up study in head and neck cancer: cure rate according to tumor location and stage. Oncology 54: 38-42
17. 17. Hall PA, Coates PJ (1995) Assessment of cell proliferation in pathology - what next? Histopathology 26:105-112
18. 18. Heidebrecht HJ, Buck F, Haas K, Wacker HH, Parwaresch R (1996) Monoclonal antibodies Ki-S3 and Ki-S5 yield new data on the 'Ki-67' proteins. Cell Prolif 29:413-425
19. 19. Ho CM, Lam KH, Wei WI, Yuen PW, Lam LK (1993) Squamous cell carcinoma of the hypopharynx-analysis of treatment results. Head Neck 15:405-412
20. 20. Holm LE (1982) Cellular DNA amounts of squamous cell carcinomas of the head and neck region in relation to prognosis. Laryngoscope 92:1064-1069
21. 21. Hsu SM, Raine L, Fanger H (1981) Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577-580
22. 22. Hussain M, Benedetti J, Smith RE, Rodriguez GI, Schuller D, Ensley J (1995) Evaluation of 96-h infusion fluorouracil plus cisplatin in combination with alpha interferon for patients with advanced squamous cell carcinoma of the head and neck: a Southwest Oncology Group study. Cancer 76:1233-1237
23. 23. Jones AS (1992) The management of early hypopharyngeal cancer: primary radiotherapy and salvage surgery. Clin Otolaryngol 17:545-549
24. 24. Jones AS, Stell PM (1991) Squamous carcinoma of the posterior pharyngeal wall. Clin Otolaryngol 16:462-465
25. 25. Jones AS, Roland NJ, Caslin AW, Cooke TG, Cooke LD, Forster G (1994) A comparison of cellular proliferation markers in squamous cell carcinoma of the head and neck. J Laryngol Otol 108:859-864
26. 26. Kearsley JH, Thomas S (1993) Prognostic markers in cancers of the head and neck region. Anticancer Drugs 4:419-429
27. 27. Kearsley JH, Furlong KL, Cooke RA, Waters MJ (1990) An immunohistochemical assessment of cellular proliferation markers in head and neck squamous cell cancers. Br J Cancer 61:821-827
28. 28. Kotelnikov VM, Coon JS, Taylor S, Hutchinson J, Panje W, Caldarelli DD, LaFollette S, Preisler HD (1995) In vivo labelling with halogenated pyrimidines of squamous cell carcinomas and adjacent non-involved mucosa of head and neck region. Cell Prolif 28:497-509
29. 29. Köhler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256: 495-497
30. 30. Laterza E, Mosciaro O, Urso US, Inaspettato G, Cordiano C (1994) Primary carcinoma of the hypopharynx and cervical esophagus: evolution of surgical therapy. Hepatogastroenterology 41:278-282
31. 31. Magnano M, De Stefani A, Lerda W, Usai A, Ragona R, Bussi M, Cortesina G (1997) Prognostic factors of cervical lymph node metastasis in head and neck squamous cell carcinoma. Tumori 83:922-926
32. 32. Parwaresch R, Rudolph P (1996) The cell cycle - theory and applications to cancer. Onkologie 19:464-472
33. 33. Piffko J, Bankfalvi A, Ofner D, Kusch F, Bocker W, Joos U, Schmid KW (1996) In situ assessment of cell proliferation at the invasive front of oral squamous cell carcinomas. Virchows Arch 429:229-234
34. 34. Raybaud-Diogene H, Fortin A, Morency R, Roy J, Monteil RA, Tetu B (1997) Markers of radioresistance in squamous cell carcinomas of the head and neck: a clinicopathologic and immunohistochemical study. J Clin Oncol 15:1030-1038
35. 35. Roland NJ, Caslin AW, Bowie GL, Jones AS (1994) Has the cellular proliferation marker Ki67 any clinical relevance in squamous cell carcinoma of the head and neck? Clin Otolaryngol 19:13-18
36. 36. Rudolph P, Kellner U, Chassevent A, Collin F, Bonichon F, Parwaresch R, Coindre JM (1997) Prognostic relevance of a novel proliferation marker, Ki-S11, for soft tissue sarcoma. A multivariate study. Am J Pathol 150:1997-2007
37. 37. Rudolph P, Knüchel R, Endl E, Heidebrecht HJ, Hofstädter F, Parwaresch R (1998) The immunohistochemical marker Ki-S2: tissue distribution and cell cycle kinetics of a novel proliferation-specific antigen. Mod Pathol 11:450-456
38. 38. Shi S-R, Key ME, Kalra KL (1991) Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 39:741-748
39. 39. Sigurdsson H, Baldetorp B, Borg A, Dalberg M, Ferno M, Killander D, Olsson H, Ranstam J (1990) Flow cytometry in primary breast cancer: improving the prognostic value of the fraction of cells in the S-phase by optimal categorisation of cut-off levels. Br J Cancer 62:786-790
40. 40. Spafford MF, Koeppe J, Pan Z, Archer PG, Meyers AD, Franklin WA (1996) Correlation of tumor markers p53, bcl-2, CD34, CD44H, CD44v6, and Ki-67 with survival and metastasis in laryngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 122:627-632
41. 41. Steiner W (1994) Therapy of hypopharyngeal cancer. Part I. Review of the literature: surgery and/or radiotherapy (see comments) (in German). HNO 42:4-13
42. 42. Struikmans H, Rutgers DH, Hordijk GJ, Slootweg PJ, van der Tweel I, Battermann JJ (1998) Prognostic significance of cell proliferation markers and DNA-ploidy in head and neck tumors. Int J Radiat Oncol Biol Phys 40:27-34
43. 43. Tapazoglou E, Kish J, Ensley J, Al Sarraf M (1986) The activity of a single-agent 5-fluorouracil infusion in advanced and recurrent head and neck cancer. Cancer 57:1105-1109
44. 44. Veneroni S, Silvestrini R, Costa A, Salvatori P, Faranda A, Molinari R (1997) Biological indicators of survival in patients treated by surgery for squamous cell carcinoma of the oral cavity and oropharynx. Oral Oncol 33:408-413
45. 45. Volling P, Schroder M (1995) Preliminary results of a prospective randomized study of primary chemotherapy in carcinoma of the oral cavity and pharynx. HNO 43:58-64
46. 46. Wahlberg PC, Andersson KE, Biorklund AT, Moller TR (1998) Carcinoma of the hypopharynx: analysis of incidence and survival in Sweden over a 30-year period. Head Neck 20: 714-719
47. 47. Wilson GD, Dische S, Saunders MI (1995) Studies with bromodeoxyuridine in head and neck cancer and accelerated radiotherapy. Radiother Oncol 36:189-197
48. 48. Zackrisson B, Gustafsson H, Stenling R, Flygare P, Wilson GD (1997) Predictive value of potential doubling time in head and neck cancer patients treated by conventional radiotherapy. Int J Radiat Oncol Biol Phys 38:677-683
49. 49. Zatterstrom UK, Wennerberg J, Ewers SB, Willen R, Attewell R (1991) Prognostic factors in head and neck cancer: histologic grading, DNA ploidy, and nodal status. Head Neck 13: 477-487