A novel set of uncoordinated mutants in Caenorhabditis elegans uncovered by cold-sensitive mutations

Genome

Volumn 39, Issue 2, 1996, Pages 459-464

  Hecht, Ralph M ^a   Norman, Mary A ^a   Vu, Tammy ^a   Jones, William ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

Caenorhabditis elegans; Cold sensitive uncoordinated mutants; cs Unc

Indexed keywords

CAENORHABDITIS ELEGANS;

ALLELE; ANIMAL; ARTICLE; CAENORHABDITIS ELEGANS; CHROMOSOME MAP; FEMALE; GENE; GENETIC LINKAGE; GENETICS; GROWTH, DEVELOPMENT AND AGING; MALE; MUTATION; PHENOTYPE; TEMPERATURE; X CHROMOSOME;

ALLELES; ANIMALS; CAENORHABDITIS ELEGANS; CHROMOSOME MAPPING; FEMALE; GENES, HELMINTH; LINKAGE (GENETICS); MALE; MUTATION; PHENOTYPE; TEMPERATURE; X CHROMOSOME;

EID: 0030113250     PISSN: 08312796     EISSN: None     Source Type: Journal    
DOI: 10.1139/g96-058     Document Type: Article

References (48)

1. Adams, A.E.M., and Botstein, D. 1989. Dominant suppressors of yeast actin mutations that are reciprocally suppressed. Genetics, 121: 675-683.
2. Adams, A.E.M., Botstein, D., and Drubin, D.G. 1989. A yeast actin-binding protein is encoded by sac6, a gene found by suppression of an actin mutant. Science (Washington, D.C.), 243: 231-234.
3. Booher, R., and Beach, D. 1987. Interaction between cdc13+ and cdc2+ in the control of mitosis in fission yeast; dissociation of the G1 and G2 roles of the cdc2+ protein kinase. EMBO J. 6: 3441-3447.
4. Brenner, S. 1974. The genetics of Caenorhabditis elegans. Genetics, 77: 71-94.
5. Chang, S.Y., and Kung, C. 1973. Temperature-sensitive pawns: conditional behavioral mutants of Paramecium aurelia. Science (Washington, D.C.), 180: 1197-1199.
6. Cox, J.H., and Strack, H.B. 1970. Cold-sensitive mutants of bacteriophage λ. Genetics, 67: 5-17.
7. Edgley, M.L., and Riddle, D.L. 1990. The nematode Caenorhabditis elegans. In Genetic maps: locus maps of complex genomes, lower eukaryotes, vol. 5. Edited by S.J. O'Brien. Cold Spring Harbour Laboratory, Cold Spring Harbor, N.Y. pp. 3.111-3.133.
8. Epstein, H.F., and Thomson, J.N. 1974. Temperature-sensitive mutation affecting myofilament assembly in Caenorhabditis elegans. Nature (London), 250: 579-580.
9. Ganetsky, B., and Wu, C.-F. 1986. Neurogenetics of membrane excitability in Drosophila. Annu. Rev. Genet. 20: 13-44.
10. Guthrie, C., Nashimoto, H., and Nomura, M. 1969. Structure and function of E. coli ribosomes, VIII. Cold-sensitive mutants defective in ribosome assembly. Proc. Natl. Acad. Sci. U.S.A. 63: 384-391.
11. Hartwell, L. 1974. Saccharomyces cerevisiae cell cycle. Bacteriol. Rev. 38: 164-198.
12. Hartwell, L.H. 1978. Cell division from a genetic perspective. J. Cell Biol. 77: 627-637.
13. Hecht, R.M., Schomer, D.F., Oro, J.A., Bartel, A.H., and Hungerford, E.V., III. 1981. Simple adaptations to extend the range of flow cytometry five orders of magnitude for the DNA analysis of uni- and multicellular systems. J. Histochem. Cytochem. 29: 771-774.
14. Hecht, R.M., Berg-Zabelshansky, M., Rao, P.N., and Davis, F.M. 1987. Conditional absence of mitosis-specific antigens in a temperature-sensitive embryonic-arrest mutant of Caenorhabditis elegans. J. Cell Sci. 87: 305-314.
15. Hirsh, D., and Vanderslice, R. 1976. Temperature-sensitive developmental mutants of Caenorhabditis elegans. Dev. Biol. 49: 220-235.
16. Hirsh, D., Oppenheim, D., and Klass, M. 1976. Development of the reproductive system of Caenorhabditis elegans. Dev. Biol. 49: 200-219.
17. Hodgkin, J., Plasterk, R.H.A., and Waterston, R.H. 1995. The nematode Caenorhabditis elegans and its genome. Science (Washington, D.C.), 270: 410-414.
18. Horowitz, N.H. 1950. Biochemical genetics of Neurospora. Adv. Genet. 3: 33-71.
19. Horvitz, H.R., Brenner, S., Hodgkin, J., and Herman, R.K. 1979. A uniform genetic nomenclature for the nematode Caenorhabditis elegans. Mol. Gen. Genet. 175: 129-133.
20. Hosono, R., Kuno, S., and Midsukami, M. 1985. Temperature-sensitive mutations causing reversible paralysis in Caenorhabditis elegans. J. Exp. Zool. 235: 409-421.
21. Jarvik, J., and Botstein, D. 1973. A genetic method for determining the order of events in a biological pathway. Proc. Natl. Acad. Sci. U.S.A. 70: 2046-2050.
22. Klass, M., Wolf, N., and Hirsh, D. 1979. Further characterization of a temperature-sensitive transformation mutant in Caenorhabditis elegans. Dev. Biol. 69: 329-335.
23. Langridge, J. 1965. Temperature-sensitive, vitamin-requiring mutants of Arabidopsis thaliana. Aust. J. Biol. Sci. 18: 311-321.
24. Loomis, W.F. 1969. Temperature-sensitive mutants of Dictyostelium discoideum. J. Bacteriol. 99: 65-69.
25. Loughney, K., Kreber, R., and Ganetsky, B. 1989. Molecular analysis of the para locus, a sodium channel gene in Drosophila. Cell, 58: 1143-1154.
26. Miwa, J., Schierenberg, E., Miwa, S., and von Ehrenstein, G. 1980. Genetics and mode of expression of temperature-sensitive mutations arresting embryonic development in Caenorhabditis elegans. Dev. Biol. 76: 160-174.
27. Moir, D., and Botstein, D. 1982. Determination of the order of gene function in the yeast nuclear division pathway using cs and ts mutants. Genetics, 100: 565-577.
28. Morgan, P.G., Sedensky, M., and Meneely, P.M. 1990. Multiple sites of action of volatile anesthetics in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 87: 2965-2969.
29. Ptáček, L.J., George, A.L., Jr., Barchi, R.L., Griggs, R.C., Riggs, J.E., Robertson, M., and Leppert, M.F. 1992. Mutations in an S4 segment of the adult muscle sodium channel cause paramyotonia congenita. Neuron, 8: 891-897.
30. Rose, A.M., and Baillie, D.L. 1979. The effect of temperature and parental age on recombination and nondisjunction in Caenorhabditis elegans. Genetics, 92: 409-418.
31. Rosenbluth, R.E., Cuddeford, C., and Baillie, D.L. 1983. Mutagenesis in Caenorhabditis elegans. I. A rapid eukaryotic mutagen test system using the reciprocal translocation eT1 (III;V). Mutat. Res. 110: 39-48.
32. Scotti, P.D. 1968. A new class of temperature conditional lethal mutants of bacteriophage T4D. Mutat. Res. 6: 1-14.
33. Sedensky, M.M., and Meneely, P.M. 1987. Genetic analysis of halothane sensitivity in Caenorhabditis elegans. Science (Washington, D.C.), 236: 952-954.
34. Starich, T.A., Herman, R.K., and Shaw, J.E., 1993. Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion. Genetics, 133: 527-541.
35. Sulston, J.E., and Hodgkin, J.M. 1988. Methods. In The nematode Caenorhabditis elegans. Edited by W.B. Wood. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y. pp. 587-606.
36. Suzuki, D.T. 1970. Temperature-sensitive mutants in Drosophila melanogaster. Science (Washington, D.C.), 170: 695-706.
37. Suzuki, D.T., Piternick, L.K., Hayashi, S., Tarasoff, M., Baillie, D., and Erasmus, U. 1967. Temperature-sensitive mutations in Drosophila melanogaster, I. Relative frequencies among γ-ray and chemically induced sex-linked recessive lethals and semilethals. Proc. Natl. Acad. Sci. U.S.A. 57: 907-912.
38. ts) causing reversible paralysis. Proc. Natl. Acad. Sci. U.S.A. 68: 890-893.
39. Swanson, M.M., and Riddle, D.L. 1981. Critical periods in the development of the Caenorhabditis elegans dauer larva. Dev. Biol. 84: 27-40.
40. Vanderslice, R., and Hirsh, D. 1976. Temperature-sensitive zygote defective mutants of Caenorhabditis elegans. Dev. Biol. 49: 236-249.
41. Ward, S., and Miwa, J. 1978. Characterization of temperature sensitive fertilization defective mutants of the nematode Caenorhabditis elegans. Genetics, 88: 285-304.
42. Wechsler, J.A., and Gross, J.D. 1971. Genetical and physiological characterization of dna mutants of E. coli. Mol. Gen. Genet. 113: 273-284.
43. Wechsler, J.A., Nusslein, V., Otto, B., Klein, A., Bonhoeffer, F., Herrmann, R., Gloger, L., and Schaller, H. 1973. Isolation and characterization of thermosensitive Escherichia coli mutants defective in deoxyribonucleic acid replication. J. Bacteriol. 113: 1381-1388.
44. Wilson, R., Alnscough, R., Anderson, K., Baynes, C., Berks, M., Bonfield, J., Burton, J., Connell, M., Copsey, T., Cooper, J., Coulson, A., Craxton, M., Dear, S., Du, Z., Durbin, R., Favello, A., Fraser, A., Fulton, L., Gardner, A., Green, P., Hawkins, T., Hillier, L., Jier, M., Johnston, L., Jones, M., Kershaw, J., Kirsten, J., Laisster, N., Latreille, P., Lightning, J., Lloyd, C., Mortimore, B., O'Callaghan, M., Parsons, J., Percy, C., Rifken, L., Roopra, A., Saunders, D., Shownkeen, R., Sims, M., Smaldon, N., Smith, A., Smith, M., Sonnhammer, E., Staden, R., Sulston, J., Thierry-Mieg, J., Thomas, K., Vaudin, M., Vaughan, K., Waterston, R., Watson, A., Weinstock, L., Wilkinson-Sproat, J., and Wohldman, P. 1994. 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans. Nature (London), 368: 32-38.
45. Wood, W. B. 1973. Genetic control of bacteriophage T4 morphogenesis. In Genetic mechanisms of development. Edited by F.H. Ruddle. Academic Press, New York, N.Y. pp. 29-46.
46. Wood, W.B. 1988. Appendix 4 Genetics. In The nematode Caenorhabditis elegans. Edited by W.B. Wood. Cold Spring Harbour Laboratory, Cold Spring Harbour, N.Y. p. 499.
47. Wood, W.B., Hecht, R., Carr, S., Vanderslice, R., Wolf, N., and Hirsh, D., 1980. Parental effects and phenotypic characterization of mutations that affect early development in Caenorhabditis elegans. Dev. Biol. 74: 446-469.
48. Zengel, J.M., and Epstein, H.F. 1980. Muscle development in Caenorhabditis elegans: a molecular genetic approach. In Nematodes as biological models. Vol. 1. Behavioral and developmental models. Edited by B.M. Zuckerman. Academic Press, New York, N.Y. pp. 73-126.