Mutations to quinolone resistance in Pseudomonas aeruginosa and Enterococcus faecium

Drugs

Volumn 58, Issue SUPPL. 2, 1999, Pages 119-120

  Jalal, Shah ^a   El Amin, Nagwa ^a   Gotoh, Naomasa ^b   Wretlind, Bengt ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); NORFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; CONFERENCE PAPER; CONTROLLED STUDY; DRUG TRANSPORT; ENTEROCOCCUS FAECIUM; GENE MUTATION; GENE SEQUENCE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA;

ENTEROCOCCUS FAECIUM; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA;

EID: 0032733723     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-199958003-00016     Document Type: Conference Paper

References (5)

1. Kohler T, Michea-Hamzehpour M, Henze U, et al. Characterization of MexE-MexF-OprN, a positively regulated multi-drug efflux system of Pseudomonas aeruginosa. Mol Microbiol 1997; 23: 345-54
2. Jalal S, Wretlind B. Mechanisms of quinolone resistance in clinical strains of Pseudomonas aeruginosa. Microb Drug Resist 1998; 4: 257-61
3. Kanematsu ET, Deguchi M, Yasuda T, et al. Alterations in the gyrA subunit of DNA gyrase and the ParC subunit of DNA topoisomerase IV associated with quinolone resistance in Enterococcus faecalis. Antimicrob Agents Chemother 1998; 42: 433-5
4. El Amin N, Jalal S, Wretlind B. Alterations in GyrA and ParC associated with fluoroquinolone resistance in Enterococcus faecium. Antimicrob Agents Chemother 1999; 43: 947-9
5. Munoz R, de la Campa RG. ParC subunit of DNA topoisomerase IV of Streptococcus pneumoniae is a primary target of fluoroquinolones and cooperates with DNA gyrase A subunit in forming resistance phenotype. Antimicrob Agents Chemother 1996; 40: 2252-7