Comparison of 0.25% S(-)-bupivacaine with 0.25% RS-bupivacaine for epidural analgesia in labour

British Journal of Anaesthesia

Volumn 83, Issue 5, 1999, Pages 750-755

  Burke, D ^a   Henderson, D J ^b   Simpson, A M ^c   Faccenda, K A ^b   Morrison, L M M ^b   McGrady, E M ^c   McLeod, G A ^a   Bannister, J ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b ST JOHN'S HOSPITAL   (United Kingdom)

^c Glasgow Royal Maternity Hospital ^*  (United Kingdom)

Author keywords

Anaesthesia, obstetric; Anaesthetic techniques, epidural; Anaesthetics local, bupivacaine; Pharmacokinetics, enantiomers

Indexed keywords

BUPIVACAINE; HYPERTENSIVE AGENT;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DELIVERY; DRUG EFFICACY; ENANTIOMER; EPIDURAL ANESTHESIA; EPIDURAL DRUG ADMINISTRATION; FEMALE; FETUS DISTRESS; HUMAN; HYPOTENSION; LABOR; MAJOR CLINICAL STUDY; MOTOR NERVE; NERVE BLOCK; PAIN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SENSORY NERVE; SIDE EFFECT; TIME;

EID: 0032729554     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/83.5.750     Document Type: Article

References (20)

1. Reynolds F. Fred Hehre lecture: In defence of bupivacaine. Int J Obstet Anaesth 1995; 4: 93-108
2. Albright GA. Cardiac arrest following regional anesthesia with etidocaine or bupivacaine. Anesthesiology 1979; 51: 285-91
3. Burm GL, Van der Meer AD, Van Kleef JW, Zeijlmans PWM, Groen K. Pharmacokinetics of the enantiomers of bupivacaine following intravenous administration of the racemate. Br J Clin Pharmacol 1994; 38: 125-9
4. Clarkson CW, Hondghem LM. Mechanism for bupivacaine depression of cardiac conduction: fast block of sodium channels during the action potential with slow recovery from the block during diastole. Anesthesiology 1985; 62: 396-405
5. Valenzuela C, Delpon E, Tamkun MM, Tamargo J, Snyders DJ. Stereoselective block of a human cardiac potassium channel (Kv 1.5) by bupivacaine enantiomers. Biophys J 1995; 69: 418-27
6. Thomas RD, Behbehani MM, Coyle DE, Denson DD. Cardiovascular toxicity of local anesthetics: an alternative hypothesis. Anesth Analg 1986; 65: 444-50
7. Mazoit JX, Boico O, Samii K. Myocardial uptake of bupivacaine: II Pharmacodynamics of bupivacaine enantiomers in the isolated perfused rabbit heart. Anesth Analg 1993; 77: 477-82
8. Denson DD, Behbehani MM, Greggs RV. Enantiomer specific effects of an intravenously administered arrhythmogenic dose of bupivacaine on neurons of the nucleus tractus solitarius of the cardiovascular system of the anesthetised rat. Reg Anesth 1992; 17: 311-16
9. Amiel-Tison C, Barrier G, Shnider SM, Levinson G, Hughes SC, Stefani SJ. A new neurologic and adaptive capacity scoring system for evaluating obstetric medications in full-term newborns. Anesthesiology 1982; 56: 340-50
10. Eddleston JM, Holland JJ, Griffin RP, Corbett A, Horsman EL. A double-blind comparison of 0.25% ropivacaine and bupivacaine for extradural analgesia in labour. Br J Anaesth 1996; 76: 66-71
11. Cox CR, Faccenda KA, Gilhooly C, Bannister J, Scott NB, Morrison LMM. Extradural S(-)-bupivacaine: comparison with racemic RS-bupivacaine. Br J Anaesth 1998; 80: 289-93
12. Cox CR, Checketts MR, Mackenzie N, Scott NB, Bannister J. Comparison of S(-) bupivacaine with racemic bupivacaine in supraclavicular brachial plexus block. Br J Anaesth 1998; 80: 594-8
13. Russell R, Reynolds F. Epidural infusion of low-dose bupivacaine and opioid in labour. Does reducing motor block increase the spontaneous delivery rate? Anaesthesia 1996; 51: 266-73
14. Chamberlain G, Wraight A, Steer P. Pain and its Relief in Childbirth. The Results of a National Survey Conducted by the National Birthday Trust. Edinburgh: Churchill Livingstone, 1993
15. Colomb MO, Lyons G.Determination of minimum analgesic concentrations of epidural bupivacaine and lidocaine in labor. Anesth Analg 1995; 81: 833-7
16. Lyons G, Colomb MO, Wilson RC, Johnson RV. Epidural pain relief in labour: relative potencies of bupivacaine and levobupivacaine. Br J Anaesth 1998; 81: 989-91
17. Bardsley H, Gristwood R, Baker H, Watson N, Nimmo W. A comparison of the cardiovascular effects of levobupivacaine and rac-bupivacaine following intravenous administration to healthy volunteers. Br J Clin Pharmacol 1998; 46: 245-9
18. Huang YF, Pryor ME, Veering BT, Mather LE. Cardiovascular and central nervous system effects of intravenous levobupivacaine and bupivacaine in sheep. Anesth Analg 1998; 86: 797-804
19. Vanhoutte F, Vereeke J, Verbeke N, Carmeliet E. Stereoselective effects of the enantiomers of bupivacaine on the electro+physiological properties of the guinea-pig papillary muscle. Br J Pharmacol 1991; 103: 1275-81
20. Aberg G. Toxicological and local anaesthetic effects of optically active isomers of two local anaesthetic compounds. Acta Pharmacol Toxicol 1972; 31: 273-86