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Volumn 44, Issue 1, 1999, Pages 31-42

Treatment of primary herpes simplex virus infection in guinea pigs by imiquimod

Author keywords

Guinea pig; HSV infection; Imiquimod; Immune response modifier; R 837

Indexed keywords

ACICLOVIR; IMIQUIMOD; METHOXYFLURANE;

EID: 0032728998     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(99)00052-2     Document Type: Article
Times cited : (55)

References (36)
  • 2
    • 0024434220 scopus 로고
    • Effects of the immunomodulating agent R-837 on acute and latent herpes simplex virus type 2 infections
    • Bernstein D.I., Harrison C.J. Effects of the immunomodulating agent R-837 on acute and latent herpes simplex virus type 2 infections. Antimicrob. Agents Chemother. 33:1989;1511-1515.
    • (1989) Antimicrob. Agents Chemother. , vol.33 , pp. 1511-1515
    • Bernstein, D.I.1    Harrison, C.J.2
  • 3
    • 0027497519 scopus 로고
    • Effects of therapy with an immunomodulator (imiquimod, R-837) alone and with acyclovir on genital HSV-2 infection in guinea pigs when begun after lesion development
    • Bernstein D.I., Miller R.L., Harrison C.J. Effects of therapy with an immunomodulator (imiquimod, R-837) alone and with acyclovir on genital HSV-2 infection in guinea pigs when begun after lesion development. Antiviral Res. 20:1993;45-55.
    • (1993) Antiviral Res. , vol.20 , pp. 45-55
    • Bernstein, D.I.1    Miller, R.L.2    Harrison, C.J.3
  • 4
    • 0027389176 scopus 로고
    • Adjuvant effects on a herpes simplex virus type 2 glycoprotein vaccine in guinea pigs
    • Bernstein D.I., Miller R.L., Harrison C.J. Adjuvant effects on a herpes simplex virus type 2 glycoprotein vaccine in guinea pigs. J. Infect. Dis. 167:1993;731-735.
    • (1993) J. Infect. Dis. , vol.167 , pp. 731-735
    • Bernstein, D.I.1    Miller, R.L.2    Harrison, C.J.3
  • 5
    • 0028835820 scopus 로고
    • Effect of imiquimod as an adjuvant for immunotherapy of genital HSV in guinea pigs
    • Bernstein D.I., Harrison C.J., Tepe E.R., Shahwan A., Miller R.L. Effect of imiquimod as an adjuvant for immunotherapy of genital HSV in guinea pigs. Vaccine. 13:1995;72-76.
    • (1995) Vaccine , vol.13 , pp. 72-76
    • Bernstein, D.I.1    Harrison, C.J.2    Tepe, E.R.3    Shahwan, A.4    Miller, R.L.5
  • 8
    • 0026060671 scopus 로고
    • Analysis of the thymidine kinase gene from clinically isolated ayclovir-resistant herpes simplex viruses
    • Chatis P.A., Crumpacker C.S. Analysis of the thymidine kinase gene from clinically isolated ayclovir-resistant herpes simplex viruses. Virology. 180:1991;793-797.
    • (1991) Virology , vol.180 , pp. 793-797
    • Chatis, P.A.1    Crumpacker, C.S.2
  • 9
    • 0032948641 scopus 로고    scopus 로고
    • Recurrent urogenital herpes simplex-successful treatment with imiquimod?
    • Christensen B., Hengge U.R. Recurrent urogenital herpes simplex-successful treatment with imiquimod? Sexually Transmitted Infect. 75:1999;132-133.
    • (1999) Sexually Transmitted Infect. , vol.75 , pp. 132-133
    • Christensen, B.1    Hengge, U.R.2
  • 10
    • 0018827818 scopus 로고
    • Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1
    • Coen D., Shaffer P. Two distinct loci confer resistance to acycloguanosine in herpes simplex virus type 1. Proc. Natl. Acad. Sci. USA. 77:1980;2265-2269.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 2265-2269
    • Coen, D.1    Shaffer, P.2
  • 11
    • 0019350295 scopus 로고
    • Altered substrate specificity of herpes simplex thymidine kinase confers acyclovir resistance
    • Darby G., Field H.J., Salisbury S.A. Altered substrate specificity of herpes simplex thymidine kinase confers acyclovir resistance. Nature (London). 289:1981;81-83.
    • (1981) Nature (London) , vol.289 , pp. 81-83
    • Darby, G.1    Field, H.J.2    Salisbury, S.A.3
  • 14
    • 0024492496 scopus 로고
    • Acyclovir resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome
    • Erlich S.K., Mills J., Chatis P. Acyclovir resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome. New Engl. J. Med. 320:1988;293-296.
    • (1988) New Engl. J. Med. , vol.320 , pp. 293-296
    • Erlich, S.K.1    Mills, J.2    Chatis, P.3
  • 16
    • 0024231126 scopus 로고
    • Modification of immunological responses and clinical disease during topical R-837 treatment of genital HSV-2 infection
    • Harrison C.J., Jenski L., Voychehovski T., Bernstein D.I. Modification of immunological responses and clinical disease during topical R-837 treatment of genital HSV-2 infection. Antiviral Res. 10:1988;209-224.
    • (1988) Antiviral Res. , vol.10 , pp. 209-224
    • Harrison, C.J.1    Jenski, L.2    Voychehovski, T.3    Bernstein, D.I.4
  • 17
    • 0025758217 scopus 로고
    • Effects of cytokines and R-837, a cytokine inducer, on UV-irradiation augmented recurrent genital herpes in guinea pigs
    • Harrison C.J., Stanberry L.R., Bernstein D.I. Effects of cytokines and R-837, a cytokine inducer, on UV-irradiation augmented recurrent genital herpes in guinea pigs. Antiviral Res. 15:1991;315-322.
    • (1991) Antiviral Res. , vol.15 , pp. 315-322
    • Harrison, C.J.1    Stanberry, L.R.2    Bernstein, D.I.3
  • 18
    • 0028071434 scopus 로고
    • Post-therapy suppression of genital herpes simplex virus (HSV) recurrences and enhancement of HSV-specific T-cell memory by imiquimod in guinea pigs
    • Harrison C.J., Miller R.L., Bernstein D.I. Post-therapy suppression of genital herpes simplex virus (HSV) recurrences and enhancement of HSV-specific T-cell memory by imiquimod in guinea pigs. Antimicro. Agents Chemother. 38:1994;2059-2064.
    • (1994) Antimicro. Agents Chemother. , vol.38 , pp. 2059-2064
    • Harrison, C.J.1    Miller, R.L.2    Bernstein, D.I.3
  • 19
    • 0023858251 scopus 로고
    • Prior herpes simplex virus type 2 infection as a risk factor for HIV infection
    • Holmberg S.D., Stewart J.A., Gerber A.R. Prior herpes simplex virus type 2 infection as a risk factor for HIV infection. J. Am. Med. Assoc. 259:1988;1048-1050.
    • (1988) J. Am. Med. Assoc. , vol.259 , pp. 1048-1050
    • Holmberg, S.D.1    Stewart, J.A.2    Gerber, A.R.3
  • 21
    • 33846141827 scopus 로고
    • Efficacy of a novel orally active immunomodulator, S-26308 against arbovirus infections
    • Kende M., Rill W.L., Contos M.J., Canonico P.G. Efficacy of a novel orally active immunomodulator, S-26308 against arbovirus infections. Antivir. Res. 9:1988;88.
    • (1988) Antivir. Res. , vol.9 , pp. 88
    • Kende, M.1    Rill, W.L.2    Contos, M.J.3    Canonico, P.G.4
  • 22
    • 0026909457 scopus 로고
    • The antiviral effects of the interferons and their inhibition
    • Kerr I.M., Stark G.R. The antiviral effects of the interferons and their inhibition. J. Interferon Res. 12:1992;237-240.
    • (1992) J. Interferon Res. , vol.12 , pp. 237-240
    • Kerr, I.M.1    Stark, G.R.2
  • 23
    • 0020487505 scopus 로고
    • Proceedings of a symposium on acyclovir
    • King, D.H., Galasso, G. (1982) Proceedings of a symposium on acyclovir. Am. J. Med. 73 (1A), 1-392.
    • (1982) Am. J. Med. , vol.73 , Issue.1 A , pp. 1-392
    • King, D.H.1    Galasso, G.2
  • 24
    • 0031849580 scopus 로고    scopus 로고
    • Recognition of herpes simplex virus type 2 tegument proteins by CD4 T-cells infiltrating human genital herpes lesions
    • Koelle D.M., Frank J.M., Johnson M.L., Kwok W.W. Recognition of herpes simplex virus type 2 tegument proteins by CD4 T-cells infiltrating human genital herpes lesions. J. Virol. 72(9):1998;7476-7483.
    • (1998) J. Virol. , vol.72 , Issue.9 , pp. 7476-7483
    • Koelle, D.M.1    Frank, J.M.2    Johnson, M.L.3    Kwok, W.W.4
  • 25
    • 0027362888 scopus 로고
    • Brief report: Recurrent acyclovir resistant genital herpes in an immunocompetent patient
    • Kost R.G., Hill E.L., Tigges M., Straus S.E. Brief report: recurrent acyclovir resistant genital herpes in an immunocompetent patient. New Engl. J. Med. 329:1993;1777-1782.
    • (1993) New Engl. J. Med. , vol.329 , pp. 1777-1782
    • Kost, R.G.1    Hill, E.L.2    Tigges, M.3    Straus, S.E.4
  • 28
    • 0032619393 scopus 로고    scopus 로고
    • A review of imiquimod applied topically: A novel immune response modifier and new class of drug
    • Miller R.L., Gerster J.F., Owens M.L., Slade H.B., Tomai M.A. A review of imiquimod applied topically: a novel immune response modifier and new class of drug. Intl. J. Immuno Pharmacol. 21:1999;1-14.
    • (1999) Intl. J. Immuno Pharmacol. , vol.21 , pp. 1-14
    • Miller, R.L.1    Gerster, J.F.2    Owens, M.L.3    Slade, H.B.4    Tomai, M.A.5
  • 29
    • 0030961152 scopus 로고    scopus 로고
    • Severe genital herpes infections in HIV-infected individuals with impaired herpes simplex virus-specific CD8+ cytotoxic T lymphocyte responses
    • Posavad C.M., Koelle D.M., Shaughnessy M.F., Corey L. Severe genital herpes infections in HIV-infected individuals with impaired herpes simplex virus-specific CD8+ cytotoxic T lymphocyte responses. Proc. Nat. Acad. Sci. USA. 94:1997;10289-10294.
    • (1997) Proc. Nat. Acad. Sci. USA , vol.94 , pp. 10289-10294
    • Posavad, C.M.1    Koelle, D.M.2    Shaughnessy, M.F.3    Corey, L.4
  • 30
    • 0027368979 scopus 로고
    • In vitro activity of penciclovir against clinical isolates of acyclovir-resistant and foscarnet-resistant herpes simplex virus
    • Safrin S., Phan L. In vitro activity of penciclovir against clinical isolates of acyclovir-resistant and foscarnet-resistant herpes simplex virus. Antimicrobial Agents Chemother. 37:1993;2241-2243.
    • (1993) Antimicrobial Agents Chemother. , vol.37 , pp. 2241-2243
    • Safrin, S.1    Phan, L.2
  • 31
    • 0031768656 scopus 로고    scopus 로고
    • Frequency of symptomatic and asymptomatic herpes simplex virus type 2 reactivations among human immunodeficiency virus-infected men
    • Schacker T., Zeh J., Hu H.L., Hill E., Corey L. Frequency of symptomatic and asymptomatic herpes simplex virus type 2 reactivations among human immunodeficiency virus-infected men. J. Infect. Dis. 178(6):1998;1616-1622.
    • (1998) J. Infect. Dis. , vol.178 , Issue.6 , pp. 1616-1622
    • Schacker, T.1    Zeh, J.2    Hu, H.L.3    Hill, E.4    Corey, L.5
  • 34
    • 0019966496 scopus 로고
    • Genital herpes in guinea pigs: Pathogenesis of the primary infection and description of recurrent disease
    • Stanberry L.R., Kern E.R., Richards J.T., Abbott T.M., Overall J.C. Genital herpes in guinea pigs: pathogenesis of the primary infection and description of recurrent disease. J. Inf. Dis. 146:1982;397-404.
    • (1982) J. Inf. Dis. , vol.146 , pp. 397-404
    • Stanberry, L.R.1    Kern, E.R.2    Richards, J.T.3    Abbott, T.M.4    Overall, J.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.