Contribution of 20-HETE to vasodilator actions of nitric oxide in the cerebral microcirculation

Stroke

Volumn 30, Issue 12, 1999, Pages 2727-2734

  Alonso Galicia, Magdalena ^a   Hudetz, Antal G ^a   Shen, Hui ^a   Harder, David R ^a   Roman, Richard J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cerebral vessels; Cyclic GMP; Cytochrome P 450; Hydroxyeicosatetraenoic acids; Nitric oxide; Rats

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; BAICALEIN; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE INHIBITOR; GUANYLATE CYCLASE INHIBITOR; HYDROXYICOSATETRAENOIC ACID; INDOMETACIN; KT 5823; NITRIC OXIDE; NITROPRUSSIDE SODIUM;

ANIMAL TISSUE; ARTICLE; BASILAR ARTERY; BRAIN MICROCIRCULATION; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; MALE; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RAT; VASODILATATION;

EID: 0032728703     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.30.12.2727     Document Type: Article

References (33)

1. Moncada S, Herman AG, Vanhoutte PM. Endothelium-derived relaxing factor is identified as nitric oxide. Trends Pharmacol Sci. 1987;8: 365-368.
2. Cohen RA, Vanhoutte PM. Endothelium-dependent hyperpolarization beyond nitric oxide and cyclic GMP. Circulation. 1995;92:3337-3349.
3. Iadecola C, Pelligrino DA, Moskowitz MA, Lassen NA. Nitric oxide synthase inhibition and cerebrovascular regulation. J Cereb Blood Flow Metab. 1994;14:175-192.
4. Iadecola C, Zhang F. Nitric oxide dependent and independent components of cerebrovasodilation elicited by hypercapnia. Am J Physiol. 1994;266:R546-R552.
5. Brian JE Jr, Faraci FM, Heistad DD. Recent insights into the regulation of the cerebral circulation. Clin Exp Pharmacol Physiol. 1996;23: 449-457.
6. Toda N, Okamura T. Nitroxidergic nerves: regulation of vascular tone and blood flow in the brain. J Hypertens. 1996;14:423-434.
7. Bryan RM Jr, Steenberg ML, Eichler MY, Johnson TD, Swafford MW, Suresh MS. Permissive role of NO in alpha-2-adrenoreceptor-mediated dilations in rat cerebral arteries. Am J Physiol. 1995;269:H1171-H1174.
8. Kontos HA. Nitric oxide and nitrosothiols in cerebrovascular and neuronal regulation. Stroke. 1994;368:850-853.
9. Okamoto H, Hudetz AG, Roman RJ, Bosnjak ZJ, Kampine JP. Neuronal NOS-derived NO plays a permissive role in the cerebral blood flow response to hypercapnia. Am J Physiol. 1997;272:H559-H566.
10. Koenig HM, Pelligrino DA, Albrecht RF. Halothane vasodilation and nitric oxide in rat pial vessels. J Neurosurg Anesthesiol. 1993;5:264-271.
11. McPherson RW, Kirsch JR, Moore LE, Traystman RJ. N-Omega-nitro-L-arginine methyl ester prevents cerebral hyperemia by inhaled anesthetics in the dog. Anesth Analg. 1993;77:891-897.
12. Akgoren N, Dalgaard P, Lauritzen M. Cerebral blood flow increases evoked by electrical stimulation of rat cerebellar cortex: relation to excitatory synaptic activity and nitric oxide synthesis. Brain Res. 1996; 710:204-214.
13. Cholet N, Bonvento G, Seylaz J. Effect of neuronal NO synthase inhibition on the cerebral vasodilatory response to somatosensory stimulation. Brain Res. 1996;708:197-200.
14. Loscalzo J, Welch G. Nitric oxide and its role in the cardiovascular system. Prog Cardiovasc Dis. 1995;38:87-104.
15. Bolotina VM, Najibi S, Palacino JJ, Pagano PJ, Cohen RA. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle cells. Nature. 1994;368:850-853.
16. + channels are stimulated by cyclic guanosine monophosphate-dependent protein kinase in canine coronary artery smooth muscle cells. Pflugers Arch. 1993;423: 167-172.
17. Onoue H, Katusic ZS. Role of potassium channels in relaxations of canine middle cerebral arteries induced by nitric oxide donors. Stroke. 1997;28: 1264-1271.
18. Onoue H, Katusic ZS. The effect of 1H-[1,2,4]oxodiazolo[4,3a]-quinoxalin-1-one (ODQ) and charybdotoxin (CTX) on relaxations of isolated cerebral arteries to nitric oxide. Brain Res. 1998;785:107-113.
19. Baughman VL, Wang Q, Pelligrino DA. Oxadiazoloquinoxalinone (ODQ) is an effective blocker of soluble guanylyl cyclase in rat pial arterioles in vivo. FASEB J. 1997;11:A246. Abstract.
20. Sobey CG, Faraci FM. Effects of a novel inhibitor of guanylyl cyclase on dilator responses of mouse cerebral arterioles. Stroke. 1997;28:837-843.
21. Faraci FM, Sobey GC. Role of soluble guanylyl cyclase in dilator responses of the cerebral microcirculation. Brain Res. 1999;821: 368-373.
22. Marshall JJ, Wei EP, Kontos HA. Independent blockade of cerebral vasodilation from acetylcholine and nitric oxide. Am J Physiol. 1988;255: H847-H854.
23. Weisbrod RM, Griswold MC, Yaghoubi M, Komalavilas P, Lincoln TM, Cohen RA. Evidence that additional mechanisms to cyclic GMP mediate the decrease in intracellular calcium and relaxation of rabbit aortic smooth muscle to nitric oxide. Br J Pharmacol. 1998;125:1695-1707.
24. Hussain AS, Marks GS, Brien JF, Nakatsu K. The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxodiazolo [4,3-alpha]quinoxalin-1-one (ODQ) inhibits relaxations of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate. Can J Physiol Pharmacol. 1997;75:1034-1037.
25. Feelisch M, Kotsonis P, Siebe J, Clement B, Schmidt HHHW. The soluble guanylyl cyclase inhibitor 1H-[1,2,4] oxadiazolo [4,3-a] quinoxalin-1-one is a nonselective heme protein inhibitor of nitric oxide synthase and other cytochrome P-450 enzymes involved in nitric oxide donor bioactivation. Mol Pharmacol. 1999;56:243-253.
26. Alonso-Galicia M, Sun CW, Falck JR, Harder DR, Roman RJ. Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries. Am J Physiol. 1998;275:F370-F378.
27. + channel activity and vascular tone in renal arterioles. Circ Res. 1998;83: 1069-1079.
28. Harder DR, Gebremedhin D, Narayanan D, Birks EK, Roman RJ. Formation and action of a P4504A metabolite of arachidonic acid in cat cerebral microvessels. Am J Physiol. 1994;266:H2098-H2107.
29. Harder DR, Lange AR, Gebremedhin D, Birks EK, Roman RJ. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J Vasc Res. 1997;34:237-243.
30. Alonso-Galicia M, Drummond HA, Reddy KK, Falck JR, Roman RJ. Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. Hypertension. 1997;29:320-325.
31. + channels in cerebral artery smooth muscle cells. Am J Physiol. 1993;265:C299-C303.
32. Goud C, DiPiero A, Lockette WE, Webb RC, Charpie JR. Cyclic GMP-independent mechanisms of nitric oxide-induced vasodilation. Gen Pharmacol. 1999;32:51-55.
33. Sobey CG, Faraci FM. Inhibitory effect of 4-aminopyridine on responses of the basilar artery to nitric oxide. Br J Pharmacol. 1999;126: 1437-1443.