Anti-Pneumocystis carinii pneumonia activity of dicationic 2,4-diarylpyrimidines

European Journal of Medicinal Chemistry

Volumn 31, Issue 10, 1996, Pages 767-773

  Kumar, A ^a   Boykin, D W ^a   Wilson, W D ^a   Jones, S K ^b   Bender, B K ^b   Dykstra, C C ^b   Hall, J E ^c   Tidwell, R R ^b  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c IL   (United States)

Author keywords

Diaryldiamidine; DNA; Pneumocystis carinii pneumonia

Indexed keywords

ANTIINFECTIVE AGENT; PENTAMIDINE; PYRIMIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PNEUMOCYSTIS PNEUMONIA; RAT;

EID: 0029849305     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/0223-5234(96)83970-5     Document Type: Article

References (28)

1. 1 Wilson WD, Tanious FA, Buczak H et al (1992) In: Structure and Function, Vol 1, Nucleic Acids (Sarma RH, Sarma MH, eds), Adenine, New York, 83-105
2. 2 Wilson WD, Tanious FA, Barton HJ, Strekowski L, Boykin DW, Jones RL (1989) J Am Chem Soc 111, 5008-5010
3. 3 Wilson WD, Tanious FA, Buczak H, Venkatramanan MK, Das BP, Boykin DW (1990) In: Jerusalem Symposia on Quantum Chemistry and Biochemistry, Vol 23 (Pullman B, Jortner J, eds) Kluwer Academic, The Netherlands, 331-353
4. 4 Kumar, A, Rhodes, AR, Spychala J et al (1995) Eur J Med Chem 30, 99-106
5. 5 Das BP, Boykin DW (1977) J Med Chem 20, 531-536
6. 6 Tidwell RR, Jones SK, Geratz JD, Ohemeng KA, Cory M, Hall JE (1990) J Med Chem 33, 1252-1257
7. 7 Zimmer C, Wahnert U (1986) Prog Biophys Mol Biol 47, 31-112
8. 8 Neidle S, Pearl LH, Shelly JV (1987) Biochem J 243, 1-13
9. 9 Nunn MN, Jenkins TC, Neidle S (1993) Biochemistry 32, 13838-13843
10. 10 Jansen K, Lincoln P, Nordeen B (1993) Biochemistry 32, 6605-6612
11. 11 Nordeen B, Kurucsev T (1994) J Mol Recogn 7, 141-156
12. 12 Tanious FA, Spychala J, Kumar A, Greene K, Boykin DW, Wilson WD (1994) J Biomol Struct Dyn 11, 1063-1083
13. 13 Boykin DW, Kumar A, Spychala J et al (1995) J Med Chem 38, 912-916
14. 14 Cory M, Tidwell RR, Fairley T (1992) J Med Chem 35, 431-438
15. 15 Cain BF, Atwell GJ, Seelye RN (1969) J Med Chem 12, 199-206
16. 16 Goodsell D, Dickerson RE (1986) J Med Chem 29, 727-733
17. 17 Kumar A, Zhao M, Wilson WD, Boykin DW (1994) Bio Med Chem Lett 4, 2913-2918
18. 18 Douc-Rasy S, Kayser A, Riou JF, Riou G (1986) Proc Natl Acad Sci USA 83, 7152-7156
19. 19 Jones SK, Hall JE, Allen MA et al (1990) Antimicrob Agents Chemother 34, 1026-1030
20. 20 Fairley TA, Tidwell RR, Donkor I et al (1993) J Med Chem 36, 1746-1753
21. 21 Tidwell RR, Jones SK, Naiman NA et al (1993) Antimicrob Agents Chemother 37, 1713-1716
22. 22 Wagner RM, Jutz C (1971) Chem Ber 104, 2975-2983
23. 23 Spychala J, Wilson WD, Boykin DW et al (1994) Eur J Med Chem 29, 363-367
24. 24 Das BP, Boykin DW (1977) J Med Chem 20, 1219-1221
25. 25 Chen FC, Chang CT (1958) J Chem Soc 146-150
26. 26 Wilson WD, Ratmeyer L, Zhao M, Strekowski L, Boykin DW (1993) Biochemistry 32, 4098-4104
27. 27 Bell CA, Dykstra CC, Naiman NA, Cory M, Fairley TA, Tidwell RR (1993) Antimicrob Agents Chemother 37, 2668-2673
28. 28 Oxley P, Short WF (1947) J Chem Soc 497-505