Epileptiform propagation patterns mediated by NMDA and non-NMDA receptors in rat neocortex

Epilepsia

Volumn 40, Issue 11, 1999, Pages 1499-1506

  Telfeian, Albert E ^a,b   Connors, Barry W ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Brain slice; Epilepsy; Layer 5; Multiple subpial transection; Neocortex; NMDA receptors

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; AMPA RECEPTOR; GLUTAMATE RECEPTOR; MAGNESIUM ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PICROTOXIN;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; ELECTROSTIMULATION; EPILEPTIC DISCHARGE; EPILEPTOGENESIS; EXCITATORY POSTSYNAPTIC POTENTIAL; IN VITRO STUDY; MICROELECTRODE; NEOCORTEX; NONHUMAN; PIA MATER; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPILEPSY; EVOKED POTENTIALS; MAGNESIUM; NEOCORTEX; NEURAL PATHWAYS; PICROTOXIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SOMATOSENSORY CORTEX;

EID: 0032722390     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.1999.tb02032.x     Document Type: Article

References (44)

1. Connors BW. Initiation of synchronized neuronal bursting in neocortex. Nature 1984;310:685-7.
2. Gutnick MJ, Connors BW, Prince DA. Mechanisms of neocortical epileptogenesis in vitro. J Neurophysiol 1982;486:1321-35.
3. Sutor B, Hablitz JJ. EPSPs in rat neocortical neurons in vitro II: involvement of N-methyl-D-aspartate receptors in the generation of EPSPs. J Neurophysiol 1989;61:621-34.
4. Pedley TA. Epilepsy and the human electroencephalogram. In: Schwartzkroin P, Wheal H, eds. Electrophysiology of epilepsy. New York: Academic Press, 1984:1-30.
5. Silva LR, Chagnac-Amitai Y, Connors BW. Intrinsic oscillations of neocortex generated by layer 5 pyramidal neurons. Science 1991;252:432-5.
6. Thomson AM, West DC. N-methylaspartate receptors mediate epileptiform activity evoked in some, but not all, conditions in rat neocortical slices. Neuroscience 1986;194:1161-77.
7. Golomb D, Amitai Y. Propagating neuronal discharges in neocortical slices: computational and experimental study. J Neurophysiol 1997;78:1199-211.
8. Lee W-L, Hablitz JJ. Initiation of epileptiform activity by excitatory amino acid receptors in the disinhibited rat neocortex. J Neurophysiol 1991;65:87-95.
9. Chagnac-Amitai Y, Connors BW. Horizontal spread of synchronized activity in neocortex and its control by GABA-mediated inhibition. J Neurophysiol 1989;61:747-58.
10. Telfeian AE, Connors BW. Layer-specific pathways for the horizontal propagation of epileptiform discharges in neocortex. Epilepsia 1998;39:700-8.
11. Flint AC, Connors BW. Two types of network oscillations in neocortex mediated by distinct glutamate receptor subtypes and neuronal populations. J Neurophysiol 1996;75:951-6.
12. Hablitz JJ, Sutor B. Excitatory postsynaptic potentials in rat neocortical neurons in vitro: III. effects of a quinoxalinedione non-NMDA receptor antagonist. J Neurophysiol 1990;64:1282-90.
13. Yakushiji T, Tokutomi N, Akaike N, Carpenter DO. Antagonists of GABA responses, studied using internally perfused frog dorsal root ganglion neurons. Neuroscience 1987;22:1123-33.
14. Freeman JA, Nicholson C. Experimental optimization of current source density technique for anuran cerebellum. J Neurophysiol 1975;38:369-82.
15. Haberly LB, Sheperd GH. Current-density analysis of summed evoked potentials in opossum pyriform cortex. J Neurophysiol 1973;36:789-803.
16. Mitzdorf U, Singer W. Excitatory synaptic ensemble properties in the visual cortex of the macaque monkey: a current source density analysis of electrically evoked potentials. J Comp Neurol 1979; 187:71-84.
17. Rappelsberger P, Pockberger H, Petsche H. Current source density analysis: methods and application to simultaneously recorded field potentials of the rabbit's visual cortex. Pflugers Arch 1981;389: 159-70.
18. Freeman B, Singer W. Direct and indirect visual inputs to superficial layers of cat superior colliculus: a current source-density analysis of electrically evoked potentials. J Neurophysiol 1983;49: 1075-91.
19. Chagnac-Amitai Y, Connors BW. Synchronized excitation and inhibition driven by intrinsically bursting neurons in neocortex. J Neurophysiol 1989;62:1149-62.
20. Schwartzkroin PA. Cellular electrophysiology of human epilepsy. Epilepsy Res 1994;17:185-92.
21. Nowak L, Bregestovski P, Ascher P, Herbert A, Prochiantz A. Magnesium gates glutamate-activated channels in mouse central neurons. Nature 1984;307:462-5.
22. Lloyd KG, Bossi L, Morselli PL, Munari C, Rougier M, Loiseau, H. Alterations of GABA-mediated synaptic transmission in human epilepsy. In: Delgado-Escueta AV, Ward AA, Woodbury DM, Porter RM, eds. Advances in neurology. Vol 44. New York: Raven Press, 1986:1033-44.
23. Ribak CE, Harris AB, Vaughn JE, Roberts E. Inhibitory, GABAergic nerve terminals decrease at sites of focal epilepsy. Science 1979;205:211-4.
24. Baldino F Jr, Wolfson B, Heinemann U, Gutnick MJ. An NMDA receptor antagonist reduces bicuculline-induced depolarization shifts in neocortical explant cultures. Neurosci Lett 1986;70: 101-5.
25. Gutnick MJ, Wolfson B, Baldino F. Synchronized neuronal activities in neocortical explant cultures. Exp Brain Res 1989;76:131-41.
26. Meldrum BS. The role of glutamate in epilepsy and other CNS disorders. Neurology 1994;44:S14-23.
27. Dingledine R, McBain CJ, McNamara JO. Excitatory amino acid receptors in epilepsy. Trends Pharmacal Sci 1990;11:334-8.
28. Meldrum BS. Excitatory amino acids in epilepsy and potential novel therapies. Epilepsy Res 1992;12:189-96.
29. Rogawski MA. The NMDA receptor, NMDA antagonists and epilepsy therapy. Drugs 1992;44:279-92.
30. Mathern GW, Pretorius JK, Mendoza D, et al. Increased hippocampal AMPA and NMDA receptor subunit immunoreactivity in temporal lobe epilepsy patients. J Neuropathol Exp Neurol 1998; 57:615-34.
31. Ying Z, Babb TL, Comair YG, Bingaman W, Bushey M, Touhalisky K. Induced expression of NMDAR2 proteins and differential expression of NMDAR1 splice variants in dysplastic neurons of human epileptic neocortex. J Neuropathol Exp Neurol 1998;57: 47-62.
32. Connors BW, Gutnick, MJ. Neocortex: cellular properties and intrinsic circuitry. In: Dingledine R, ed. Brain slices. New York: Plenum Press, 1984:313-40.
33. Horne AL, Harrison NL, Turner JP, Simmonds MA. Spontaneous paroxysmal activity induced by zero magnesium and bicuculline: suppression of NMDA antagonists and GABA mimetics. Eur J Pharmacol 1987;122:231-8.
34. Sutor B, Hablitz JJ. EPSPs in rat neocortical neurons in vitro I: electrophysiological evidence for two distinct EPSPs. J Neurophysiol 1989;61:607-20.
35. Hufnagel A, Zentner J, Fernandez G, Wolf HK, Schramm J, Elger CE. Multiple subpial transection for control of epileptic seizures: effectiveness and safety. Epilepsia 1997;38:678-8.
36. Morrell F, Whisler WW, Bleck TP. Multiple subpial transection: a new approach to the surgical treatment of focal epilepsy. J Neurosurg 1989;70:231-9.
37. Sawhney IMS, Robertson IJA, Polkey CE, Binnie CD, Elwes RDC. Multiple subpial transection: a review of 21 cases. J Neurol Neurosurg Psychiatry 1995;58:344-9.
38. Rougier A, Sundstrom L, Claverie B, et al. Multiple subpial transection: report of 7 cases. Epilepsy Res 1996;24:57-63.
39. Asanuma H. Recent developments in the study of the columnar arrangement of neurons within the motor cortex. Physiol Rev 1975; 55:143-56.
40. Hubel DH, Wiesel TN. Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. J Physiol (Lond) 1962;160:106-54.
41. Mountcastle VB. Modality and topographic properties of single neurons of cat's somatic sensory cortex. J Neurophysiol 1957;20: 408-34.
42. Sperry RW, Miner N, Myers RE. Visual pattern perception following subpial splicing and tantalum wire implantations in visual cortex. J Comp Physiol Psychol 1955;48:50-8.
43. Kaufmann WE, Krauss GL, Uematsu S, Lesser RP. Treatment of epilepsy with multiple subpial transections: an acute histologic analysis in human subjects. Epilepsia 1996;37:342-52.
44. Albowitz B, Kuhnt U. The contribution of intracortical connections to horizontal spread of activity in the neocortex as revealed by voltage sensitive dyes and fast optical recording method. Eur J Neurosci 1993;5:1349-59.