A mutant of Listeria monocytogenes LO28 unable to induce an acid tolerance response displays diminished virulence in a murine model

Applied and Environmental Microbiology

Volumn 63, Issue 12, 1997, Pages 4945-4947

  Marron, Lynda ^a   Emerson, Nathan ^a   Gahan, Cormac G M ^a   Hill, Colin ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ACID TOLERANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM MUTANT; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; PH; STRESS;

ANIMALIA; BACTERIA (MICROORGANISMS); LISTERIA MONOCYTOGENES; MURINAE;

EID: 0030734260     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/aem.63.12.4945-4947.1997     Document Type: Article

References (6)

1. Camilli, A., D. Portnoy, and P. Youngman. 1990. Insertional mutagenesis of Listeria monocytogenes with a novel Tn917 derivative that allows direct cloning of DNA flanking transposon insertions. J. Bacteriol. 172:3738-3744.
2. Davis, M. J., P. J. Coote, and C. P. O'Byrne. 1996. Acid tolerance in Listeria monocytogenes: the adaptive acid tolerance response (ATR) and growth-phase-dependent acid resistance. Microbiology 142:2975-2982.
3. Gahan, C. G. M., B. O'Driscoll, and C. Hill. 1996. Acid adaptation of Listeria monocytogenes can enhance survival in acidic foods and during milk fermentation Appl. Environ. Microbiol. 62:3128-3132.
4. O'Driscoll, B., C. G. M. Gahan, and C. Hill. 1996. Adaptive acid tolerance response in Listeria monocytogenes: isolation of an acid-tolerant mutant which displays increased virulence. Appl. Environ. Microbiol. 62:1693-1698.
5. Perkins, J. B., and P. Youngman. 1986. Construction and properties of Tn-917-lac, a transposon derivative that mediates transcriptional gene fusions in Bacillus subtilis. Proc. Natl. Acad. Sci. USA 83:140-144.
6. Rouquette, C., M.-T. Ripio, E. Pellegrini, J.-M. Bolla, R. I. Tascon, J.-A. Vazquez-Boland, and P. Berche. 1996. Identification of a ClpC ATPase required for stress tolerance and in vivo survival of Listeria monocytogenes. Mol. Microbiol. 21:977-987.