메뉴 건너뛰기




Volumn 88, Issue 11, 1999, Pages 1156-1160

In vitro and in vivo study of water-soluble prodrugs of dexanabinol

Author keywords

[No Author keywords available]

Indexed keywords

DEXANABINOL; PRODRUG;

EID: 0032721494     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js990098j     Document Type: Article
Times cited : (14)

References (17)
  • 1
    • 0024986448 scopus 로고
    • Synthesis of the individual, pharmacologically distinct, enantiomers of a tetrahydrocannabinol derivative
    • Mechoulam, R.; Lander, N.; Bauer, A.; Zahalka, J. Synthesis of the individual, pharmacologically distinct, enantiomers of a tetrahydrocannabinol derivative. Tetrahedron: Asymmetry 1990, 1, 315-318.
    • (1990) Tetrahedron: Asymmetry , vol.1 , pp. 315-318
    • Mechoulam, R.1    Lander, N.2    Bauer, A.3    Zahalka, J.4
  • 3
    • 0029165097 scopus 로고
    • Neuroprotective and antioxidant activities of HU-211, a novel NMDA receptor antagonist
    • Eshhar, N.; Striem, S.; Kohen, R.; Tirosh, O.; Biegon., A. Neuroprotective and antioxidant activities of HU-211, a novel NMDA receptor antagonist. Eur. J. Pharmacol. 1995, 283, 1-3.
    • (1995) Eur. J. Pharmacol. , vol.283 , pp. 1-3
    • Eshhar, N.1    Striem, S.2    Kohen, R.3    Tirosh, O.4    Biegon, A.5
  • 4
    • 0027250138 scopus 로고
    • A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat
    • Shohami, E.; Novikov, M.; Mechoulam, R. A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat. J. Neurotrauma 1993, 10, 109-119.
    • (1993) J. Neurotrauma , vol.10 , pp. 109-119
    • Shohami, E.1    Novikov, M.2    Mechoulam, R.3
  • 5
    • 0028309985 scopus 로고
    • Antiischemia activity of HU-211, a synthetic, nonpsychotropic cannabinoid
    • Vered, M.; Bar Joseph, A.; Belyaev, L.; Biegon, A. Antiischemia activity of HU-211, a synthetic, nonpsychotropic cannabinoid. Acta Neurochir. 1994, 70 (suppl), 335-337.
    • (1994) Acta Neurochir. , vol.70 , Issue.SUPPL. , pp. 335-337
    • Vered, M.1    Bar Joseph, A.2    Belyaev, L.3    Biegon, A.4
  • 6
    • 0030827712 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of escalating I. V. doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers
    • Brewster, M. E.; Pop, E.; Foltz, R.; Griffith, W.; Amselem, S.; Biegon, A. Clinical Pharmacokinetics of Escalating I. V. Doses of Dexanabinol (HU-211), a Neuroprotectant Agent, in Normal Volunteers, J. Clin. Pharm. Ther. 1997, 35, 361-365.
    • (1997) J. Clin. Pharm. Ther. , vol.35 , pp. 361-365
    • Brewster, M.E.1    Pop, E.2    Foltz, R.3    Griffith, W.4    Amselem, S.5    Biegon, A.6
  • 7
    • 0001283971 scopus 로고    scopus 로고
    • Dimerization of dexanabinol by hydrogen bonding accounts for its hydrophobic character
    • Pop, E.; Brewster, M. E. Dimerization of Dexanabinol by Hydrogen Bonding Accounts for its Hydrophobic Character. Int. J. Quantum Chem. Quantum Biol. Symp. 24 1997, 65, 1057-64.
    • (1997) Int. J. Quantum Chem. Quantum Biol. Symp. 24 , vol.65 , pp. 1057-1064
    • Pop, E.1    Brewster, M.E.2
  • 10
    • 0029880941 scopus 로고    scopus 로고
    • Derivatives of dexanabinol. II. Salts of amino acid esters containing tertiary and quaternary cyclic nitrogen with increased water-solubility
    • Pop, E.; Soti, F.; Brewster, M. E.; Barenholz, Y.; Mechoulam, R.; Nadler, V.; Biegon, A. Derivatives of Dexanabinol. II. Salts of Amino acid Esters Containing Tertiary and Quaternary Cyclic Nitrogen with Increased Water-Solubility. Pharm. Res. 1996, 13, 469-475.
    • (1996) Pharm. Res. , vol.13 , pp. 469-475
    • Pop, E.1    Soti, F.2    Brewster, M.E.3    Barenholz, Y.4    Mechoulam, R.5    Nadler, V.6    Biegon, A.7
  • 14
  • 17
    • 84920361747 scopus 로고    scopus 로고
    • Unpublished results
    • Biegon, A. Unpublished results.
    • Biegon, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.