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Neuroprotective and antioxidant activities of HU-211, a novel NMDA receptor antagonist
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Eshhar, N.; Striem, S.; Kohen, R.; Tirosh, O.; Biegon., A. Neuroprotective and antioxidant activities of HU-211, a novel NMDA receptor antagonist. Eur. J. Pharmacol. 1995, 283, 1-3.
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A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat
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Shohami, E.; Novikov, M.; Mechoulam, R. A nonpsychotropic cannabinoid, HU-211, has cerebroprotective effects after closed head injury in the rat. J. Neurotrauma 1993, 10, 109-119.
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Vered, M.; Bar Joseph, A.; Belyaev, L.; Biegon, A. Antiischemia activity of HU-211, a synthetic, nonpsychotropic cannabinoid. Acta Neurochir. 1994, 70 (suppl), 335-337.
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Clinical pharmacokinetics of escalating I. V. doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers
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Brewster, M. E.; Pop, E.; Foltz, R.; Griffith, W.; Amselem, S.; Biegon, A. Clinical Pharmacokinetics of Escalating I. V. Doses of Dexanabinol (HU-211), a Neuroprotectant Agent, in Normal Volunteers, J. Clin. Pharm. Ther. 1997, 35, 361-365.
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Dimerization of dexanabinol by hydrogen bonding accounts for its hydrophobic character
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A water soluble prodrugs and congeners of dexanabinol
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Budapest, 1995; APGI: Châtenay Malabry, France
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Pop, E.; Brewster, M. E.; Liu, Z. Z.; Soti, F.; Rachwal, S.; Dinculescu, A.; Nadler, V.; Barenholz, Y.; Mechoulam, R.; Biegon, A. A Water Soluble Prodrugs and Congeners of Dexanabinol. In Proceedings of the 1st World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, Budapest, 1995; APGI: Châtenay Malabry, France, 1995; pp 127-128.
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0029868614
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Derivatives of dexanabinol. I. Water-soluble salts of glycinate esters
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Pop, E.; Liu, Z. Z.; Brewster, M. E.; Barenholz, Y.; Korablyov, V.; Mechoulam, R.; Nadler, V.; Biegon, A. Derivatives of Dexanabinol. I. Water-soluble Salts of Glycinate Esters. Pharm. Res. 1996, 13, 62-69.
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10
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0029880941
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Derivatives of dexanabinol. II. Salts of amino acid esters containing tertiary and quaternary cyclic nitrogen with increased water-solubility
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Pop, E.; Soti, F.; Brewster, M. E.; Barenholz, Y.; Mechoulam, R.; Nadler, V.; Biegon, A. Derivatives of Dexanabinol. II. Salts of Amino acid Esters Containing Tertiary and Quaternary Cyclic Nitrogen with Increased Water-Solubility. Pharm. Res. 1996, 13, 469-475.
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Pop, E.; Soti, F.; Biegon, A.; Brewster, M. E. Allylic and Phenolic Phosphate Esters of Dexanabinol. Org. Prep. Proced. Int. 1997, 29, 341-347.
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85030361330
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Quaternary ammonium moiety containing water soluble amino acid ester-type prodrugs of dexanabinol
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Paris, 1998; APGI: Châtenay Malabry, France
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Partial results presented: Pop, E.; Rachwal, S.; Vlasak, J.; Brewster, M. E.; Prokai L.; Biegon, A. Quaternary Ammonium Moiety Containing Water Soluble Amino Acid Ester-Type Prodrugs of Dexanabinol. In Proceedings of the 2nd World Meeting on Pharmaceutics, Biopharmaceutics, and Pharmaceutical Technology, Paris, 1998; APGI: Châtenay Malabry, France, 1998; pp 101-102.
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Brewster, M.E.4
Prokai, L.5
Biegon, A.6
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13
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Synthesis of labeled dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties
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Pop, E.; Rachwal, B.; Rachwal S.; Vlasak J.; Prokai L.; Brewster, M. E. Synthesis of Labeled Dexanabinol, a Nonpsychotropic Cannabinoid with Neuroprotective Properties. J. Labeled Comp. Radiopharm. 1998, 15, 885-897.
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15
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Biegon, A. Unpublished results.
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Biegon, A.1
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