Derivatives of dexanabinol. II. Salts of amino acid esters containing tertiary and quaternary heterocyclic nitrogen with increased water-solubility

Pharmaceutical Research

Volumn 13, Issue 3, 1996, Pages 469-475

  Pop, Emil ^a   Soti, Ferenc ^a   Brewster, Marcus E ^a   Barenholz, Yechezkel ^b   Korablyov, Veronica ^b   Mechoulam, Raphael ^c   Nadler, Varda ^d   Biegon, Anat ^d  

^a Pharmos Corporation   (United States)

^b HEBREW UNIVERSITY   (Israel)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d PHARMOS LTD   (Israel)

Author keywords

Congeners; Dexanabinol; Neuroprotection; Prodrugs

Indexed keywords

CANNABINOID DERIVATIVE; DEXANABINOL; DIZOCILPINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PRODRUG;

ARTICLE; BRAIN CORTEX; CELL CULTURE; DOG; DRUG ACTIVITY; DRUG HYDROLYSIS; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG SYNTHESIS; HUMAN; NEUROPROTECTION; NEUROTOXICITY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT;

ANIMALS; BINDING, COMPETITIVE; CELLS, CULTURED; DIZOCILPINE MALEATE; DOGS; DRUG STABILITY; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; HYDROLYSIS; MORPHOLINES; NERVOUS SYSTEM DISEASES; NEURONS; NEUROPROTECTIVE AGENTS; PIPERAZINES; PRODRUGS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROCANNABINOL; TRITIUM; WATER;

EID: 0029880941     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1016017331353     Document Type: Article

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