Catechol-O-methyltransferase activity in CHO cells expressing norepinephrine transporter

British Journal of Pharmacology

Volumn 128, Issue 3, 1999, Pages 774-780

  Percy, Elodie ^a   Kaye, David M ^a   Lambert, Gavin W ^a   Gruskin, Sara ^a   Esler, Murray D ^a   Du, Xiao Jun ^a  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Catechol O methyltransferase; cDNA; CHO cell; MAO inhibitors; Norepinephrine transporter; Ro 41 0960; U 0521

Indexed keywords

2' FLUORO 3,4 DIHYDROXY 5 NITROBENZOPHENONE; 3',4' DIHYDROXY 2 METHYLPROPIOPHENONE; AMINE OXIDASE (FLAVIN CONTAINING); CARRIER PROTEIN; CATECHOL METHYLTRANSFERASE; COMPLEMENTARY DNA; NORADRENALIN; NORMETADRENALIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CHO CELL; CONTROLLED STUDY; CULTURE MEDIUM; DNA TRANSFECTION; DOSE RESPONSE; ENZYME ACTIVITY; HUMAN; HUMAN TISSUE; ISOTOPE LABELING; METABOLISM; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY;

ANIMALS; CARRIER PROTEINS; CATECHOL O-METHYLTRANSFERASE; CHO CELLS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; ENZYME INHIBITORS; MONOAMINE OXIDASE; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; SYMPORTERS; TRANSFECTION;

EID: 0032720767     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702831     Document Type: Article

References (33)

1. AMARA, S.G. & KUMAR, M.J. (1993). Neurotransmitter transporters: recent progress. Ann. Rev. Neurosci., 16, 73-93.
2. BÄCKSTRÖM, R., HONKANEN, E., PIPPURI, A., KAIRISALO, P., PYSTYNEN, J., HEINOLA, K., NISSINEN, E., LINDEN, L-B., MÄNNISTÖ, P.T., KAAKKOLA, S. & POHTO, P. (1989). Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors. J. Med. Chem., 32, 841-846.
3. BEAU, S.L. & SAFFITZ, J.E. (1994). Transmural heterogeneity of norpinephrine uptake in failing human hearts. J. Am. Coll. Cardiol., 23, 579-585.
4. BLAKELY, R.D., BERSON, H.E., FREMEAU, JR, R.T., CARON, M.G., PEEK, M.M., PRINCE, H.K. & BRADLEY, C.C. (1991). Cloning and expression of a functional serotonin transporter from rat brain. Nature, 354, 66-70.
5. BÖNISCH, H. & EIDEN, L. (1998). Catecholamine reuptake and storage. Overview. Adv. Pharmacol., 42, 149-164.
6. BOULTON, A.A. & EISENHOFER, G. (1998). Catecholamine metabolism. From molecular understanding to clinical diagnosis and treatment. Adv. Pharmacol., 42, 273-292.
7. CHANG, A.S. & LAM, D.M.-K. (1998). Mechanistic analyses of ion dependences in a high-affinity human serotonin transport system in transfected murine fibroblast cells. J. Physiol., 510.3, 903-913.
8. CHOMCZYNSKI, P. & SAACHI, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
9. DART, A.M. & DU, X.-J. (1993). Unexpected drug effects on autonomic function during myocardial ischaemia. Cardiovasc. Res., 27, 906-914.
10. 3 release. Circulation, 91, 2712-2716.
11. DU, X.-J., WOODCOCK, E.A., LITTLE, P.J., ESLER, M.D. & DART, A.M. (1998). Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms. J. Cardiovasc. Pharmacol., 32, 621-628.
12. ESHLEMAN, A.J., STEWART, E., EVENSON, A.K., MASON, J.N., BLAKELY, R.D., JANOWSKY, A. & NEVE, K.A. (1997). Metabolism of catecholamines by catechol-O-methyltransferase in cells expressing recombinant catecholamine transporters. J. Neurochem., 69, 1459-1466.
13. ESLER, M., JENNINGS, G., LAMBERT, G., MEREDITH, I., HORNE, M. & EISENHOFER, G. (1990). Overflow of catecholamine neurotransmitters to the circulation: source, fate and functions. Physiol. Rev., 70, 963-985.
14. GALLI, A., BLAKELY, R. D. & DEFELICE, L.J. (1996). Norepinephrine transporters have channel modes of conduction. Proc. Natl. Acad. Sci. U.S.A., 93, 8671-8676.
15. GOLDSTEIN, D.S., BRUSH, JR, J.E., EISENHOFER. G., STULL, R. & ESLER, M. (1988). In vivo measurement of neuronal uptake of norepinephrine in the human heart. Circulation, 78, 41-48.
16. GU, H., WALL, S.C. & RUDNICK, G. (1994). Stable expression of biogenic amine transporters reveals differences in inhibitor sensitivity, kinetics and ion dependence. J. Biol. Chem., 269, 7124-7130.
17. HARDER, R. & BÖNISCH, H. (1985). Effects of monovalent ions on the transport of noradrenaline across the plasma membrane of neuronal cells (PC-12 cells). J. Neurochem., 45, 1154-1162.
18. KAYE, D.M., LEFKOVITS, J., JENNINGS, G.L., BERGIN, P., BROUGHTON, A. & ESLER, M.D. (1995). Adverse consequences of high sympathetic nervous activity in the failing human heart. J. Am. Coll. Cardiol., 26, 1257-1263.
19. KAYE, D.M., WIVIOTT, S.D., KOBZIK, L., KELLY, R.A. & SMITH, T.W. (1997). S-nitrosothils inhibits neuronal norepinephrine transport. Am. J. Physiol., 272, H875-H883.
20. KILTY, J.E., LORANG, D. & AMARA, S.G. (1991). Cloning and expression of a cocaine-sensitive rat dopamine transporter. Science, 254, 578-579.
21. KURZ, T., OFFNER, B., SCHREIECK, J., RICHARDT, G., TOLG, R. & SCHÖMIG, A. (1995). Nonexocytotic noradrenaline release and ventricular fibrillation in ischemic rat hearts. Naunyn Schmiedeberg's Arch. Pharmacol., 352, 491-496.
22. LAMBERT, G.W. & JONSDOTTIR, I.H. (1998). Influence of voluntary exercise on hypothalamic norepinephrine. J. Appl. Physiol., 85, 962-966.
23. LIANG, C., FAN, T., SULLEBARGER, J.T. & SAKAMOTO, S. (1989). Decreased adrenergic neuronal uptake activity in experimental right heart failure. J. Clin. Invest., 84, 1267-1275.
24. MÄNNISTÖ, P.T. & KAAKKOLA, S. (1990).Rationale for selective COMT inhibitors as adjuncts in the drug treatment of Parkinson's disease. Pharmacol. Toxicol., 66, 317-323.
25. MERLET, P., DUBOIS-RANDE, J.L., ADNOT, S., BOURGUIGNON, M.H., VENVENUTI. C., LOISANCE, D., VALETTE, H., CASTAIGNE, A. & SYROTA, A. (1992). Myocardial β-adrenergic desensitization and neuronal norepinephrine uptake function in idiopathic dilated cardiomyopathy. J. Cardiovasc. Pharmacol., 19, 10-16.
26. PACHOLCZYK, T., BLAKELY, R.D. & AMARA, S.G. (1991). Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter. Nature, 350, 350-354.
27. 1 or Cl of cocaine sensitive carrier-mediated efflux of amines from cells transfected with the cloned human catecholamine transporters. Br. J. Pharmacol., 121, 205-212.
28. SAMBROOK, J., FRITSCH, E.F. & MANIATIS, T. (1989). In vitro amplification of DNA by the polymerase chain reaction. In: Molecular cloning: A laboratory manual. (ed.). Nolan, C. pp. 14.20-14.21. New York: Cold Spring Harbor Laboratory Press.
29. SCHO̊MIG, A. (1990). Catecholamines in myocardial ischemia. Circulation. 82 (suppl. II), II-13-II-22.
30. SCHULDINER, S., SHRIVAN, A. & LINIAL, M. (1995). Vesicular neurotransmitter transporters: from bacteria to humans. Physiol. Rev., 75, 369-392.
31. SHIMADA, S., KITAYAMA, S., LIN, C.-L., PATEL, A., NANTHAKUMAR, E., GREGOR, P., KUHAR, M. & UHL, G. (1991). Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA. Science, 254, 576-578.
32. USDIN, T.B., MEZEY, E., CHEN, C., BROWNSTEIN, M.J. & HOFFMAN, B.J. (1991). Cloning of the cocaine-sensitive bovine dopamine transporter. Proc. Natl. Acad. Sci. U.S.A., 88, 11168-11171.
33. YANG, H. & RAIZADA, M.K. (1999). Role of phosphatidylinositol 3-kinase in angiotensin II regulation of norepinephrine neuromodulation in brain neurons of the spontaneously hypertensive rat. J. Neurosci., 19, 2413-2423.