Mechanisms of resistance to fluoroquinolones

National Medical Journal of India

Volumn 12, Issue 4, 1999, Pages 162-164

  Rattan, A ^a  

^a RANBAXY RESEARCH LABORATORIES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; DRUG ACCUMULATION; DRUG POTENCY; ENZYME MECHANISM; GENE MUTATION; MOLECULAR WEIGHT; NONHUMAN; REVIEW;

ANTI-INFECTIVE AGENTS; CELL MEMBRANE PERMEABILITY; DNA TOPOISOMERASES, TYPE I; DNA, BACTERIAL; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; FLUOROQUINOLONES; HUMANS; MUTATION; STAPHYLOCOCCUS AUREUS;

EID: 0032718727     PISSN: 0970258X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (8)

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3. Drlica K, Zhao X. DNA gyrase, topoisomerase IV and the 4 quinolones. Micro Mol Biol Rev 1997;61:377-92.
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5. Hooper DC. Quinolone: Mode of action. Drugs 1995;5:102-8.
6. Martinez JL, Alonso A, Gomez JMG, Baquero F. Quinolone resistance by mutations in chromosomal gyrase genes. Just the tip of the iceberg? J Antimicrob Chemother 1998;42:683-8.
7. Martinez ML, Pascual A, Jacoby GA. Quinolone resistance from a transferable plasmid. Lancet 1998;351:797-9.
8. Gootz TD, Brighty KE. Fluoroquinolone antibacterials: SAR, mechanism of action, resistance and clinical aspects. Med Res Rev 1996;16:433-86.