Pregnancy loss in the antiphospholipid syndrome

Thrombosis and Haemostasis

Volumn 82, Issue 2, 1999, Pages 641-648

  Lockshin, Michael D ^a,b  

^a Department of Obstetrics Gynecology   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; LUPUS ANTICOAGULANT; PHOSPHOLIPID ANTIBODY; PREDNISOLONE;

ANTIPHOSPHOLIPID SYNDROME; BONE ATROPHY; CONFERENCE PAPER; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS DEATH; FETUS GROWTH; HUMAN; PRIORITY JOURNAL; SPONTANEOUS ABORTION; SUBCUTANEOUS DRUG ADMINISTRATION; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0032718093     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1615891     Document Type: Conference Paper

References (52)

1. Gharavi AE, Sammaritano LR, Wen J, Miyawaki N, Morse JH, Zarrabi MH, Lockshin MD. Characteristics of human immunodeficiency virus and chlorpromazine induced antiphospholipid antibodies: effect of beta 2 glycoprotein I on binding to phospholipid. J Rheumatol. 1994;21:94-99.
2. Gharavi AE, Pierangeli SS. Origin of antiphospholipid antibodies: induction of aPL by viral peptides. Lupus. 1998;7:S52-S54.
3. Wilson WA, Gharavi AE, Koike T, Lockshin MD, Branch DW. International consensus statement on preliminary classification criteria for antiphospholipid syndrome: report of an international workshop. Submitted for publication.
4. Sheng Y, Kandiah DA, Krilis SA. Beta2-glycoprotein I: target antigen for 'antiphospholipid' antibodies. Immunological and molecular aspects. Lupus. 1998;7:S5-S9.
5. Koike T, Ichikawa K, Kasahara H, Atsumi T, Tsutsumi A, Matsuura E. Epitopes on beta 2-GPI recognized by anticardiolipin antibodies. Lupus. 1998;7:S14-S17.
6. Harris EN, Spinnato JA. Should anticardiolipin tests be performed in otherwise healthy pregnant women? Am J Obstet Gynecol. 1991;165:1272-1277.
7. Lockwood CJ, Romero R, Feinberg RF, Clyne LP, Coster B, Hobbins JC. The prevalence and biologic significance of lupus anticoagulant and anticardiolipin antibodies in a general obstetric population. Am J Obstet Gynecol. 1989;161:369-373.
8. Rix P, Stentoft J, Aunsholt NA, Dueholm M, Tilma KA, Hoier-Madsen M. Lupus anticoagulant and anticardiolipin antibodies in an obstetric population. Acta Obstet Gynecol Scand. 1992;71:605-609.
9. Lynch A, Marier R, Murphy J, Davila G, Santos M, Rutledge J, Emlen W. Antiphospholipid antibodies in predicting adverse pregnancy outcome. A prospective study. Ann Intern Med. 1994;120:470-475.
10. Infante-Rivard C, David M, Gauthier R, Rivard GE. Lupus anticoagulants, anticardiolipin antibodies, and fetal loss. A case-control study. N Engl J Med. 1991;325:1063-1066.
11. Haddow JE, Rote NS, Dostal-Johnson D, Palomaki GE, Pulkkinen AJ, Knight GJ. Lack of an association between late fetal death and antiphospholipid antibody measurements in the second trimester. Am J Obstet Gynecol. 1991;165:1308-1312.
12. Parke AL, Wilson D, Maier D. The prevalence of antiphospholipid antibodies in women with recurrent spontaneous abortion, women with successful pregnancies, and women who have never been pregnant. Arthritis Rheum. 1991;34:1231-1235.
13. Out HJ, Bruinse HW, Christiaens GC, van Vliet M, de Groot PG, Nieuwenhuis HK, Derksen RH. A prospective, controlled multicenter study on the obstetric risks of pregnant women with antiphospholipid antibodies. Am J Obstet Gynecol. 1992;167:26-32.
14. Petri M, Golbus M, Anderson R, Whiting-O'Keefe Q, Corash L, Hellman D. Antinuclear antibody, lupus anticoagulant, and anticardiolipin antibody in women with idiopathic habitual abortion. A controlled, prospective study of forty-four women. Arthritis Rheum. 1987;30:601-606.
15. Houwert-de Jong MH, Termijtelen A, Eskes TK, Mantingh A, Bruinse HW. The natural course of habitual abortion. Eur J Obstet Gynecol Reprod Biol. 1989;33:221-228.
16. Vlaanderen W, Treffers PE. Prognosis of subsequent pregnancies after recurrent spontaneous abortion in first trimester. Br Med J. 1987;295:92-93.
17. Parazzini F, Acaia B, Ricciardiello O, Fedele L, Liati P, Candiani GB. Short-term reproductive prognosis when no cause can be found for recurrent miscarriage. Br J Obstet Gynaecol. 1988;95:654-658.
18. Cauchi MN, Pepperell R, Kloss M, Lim D. Predictors of pregnancy success in repeated miscarriage. Am J Reprod Immunol. 1991;26:72-75.
19. Knudsen UB, Hansen V, Juul S, Secher NJ. Prognosis of a new pregnancy following previous spontaneous abortions. Eur J Obstet Gynecol Reprod Biol. 1991;39:31-36.
20. Nakamura N, Ban T, Yamaji K, Yoneda Y, Wada Y. Localization of the apoptosis-inducing activity of lupus anticoagulant in an annexin V-binding antibody subset. J Clin Invest. 1998;101:1951-1959.
21. Manfredi AA, Rovere P, Galati G, Heltai S, Bozzolo E, Soldini L, Davoust J, Balestrieri G, Tincani A, Sabbadini MG. Apoptotic cell clearance in systemic lupus erythematosus. I. Opsonization by antiphospholipid antibodies. Arthritis Rheum. 1998;41:205-214.
22. Bordron A, Dueymes Y, Levy Y, Jamin C, Ziporen L, Piette JC, Shoenfeld Y, Youinou P. Anti-endothelial cell antibody binding makes negatively charged phospholipids accessible to antiphospholipid antibodies. Arthritis Rheum. 1998;41:1738-1747.
23. Rote NS, Vogt E, DeVere G, Obringer AR, Ng AK. The role of placental trophoblast in the pathophysiology of the antiphospholipid antibody syndrome. Am J Reprod Immunol. 1998;39:125-136.
24. Sammaritano LR, Gharavi AE, Soberano C, Levy RA, Lockshin MD. Phospholipid binding of antiphospholipid antibodies and placental anticoagulant protein. J Clin Immunol. 1992;12:27-35.
25. Rand JH, Wu XX, Andree HA, Lockwood CJ, Guller S, Scher J, Harpel PC. Pregnancy loss in the antiphospholipid-antibody syndrome3/4a possible thrombogenic mechanism. N Engl J Med. 1997;337:154-160.
26. Pierangeli SS, Liu XW, Barker JH, Anderson G, Harris EN. Induction of thrombosis in a mouse model by IgG, IgM, and IgA immunoglobulins from patients with the antiphospholipid syndrome. Thromb Haemost. 1995;74:1361-1367.
27. Shoenfeld Y, Ziporen L. Lessons from experimental APS models. Lupus. 1998;7:S158-S161.
28. La Rosa L, Meroni PL, Tincani A, Balestrieri G, Faden D, Lojacono A, Morassi L, Brocchi E, Del Papa N, Gharavi A, Sammaritano L, Lockshin M. Beta 2 glycoprotein I and placental anticoagulant protein I in placentae from patients with antiphospholipid syndrome. J Rheumatol. 1994;21:1684-1693.
29. Ikematsu W, Luan FL, La Rosa L, Beltrami B, Nicoletti F, Buyon JP, Meroni PL, Balestrieri G, Casali P. Human anticardiolipin monoclonal autoantibodies cause placental necrosis and fetal loss in BALB/c mice. Arthritis Rheum. 1998;41:1026-1039.
30. Magid MS, Kaplan C, Sammaritano LR, Peterson M, Druzin ML, Lockshin MD. Placental pathology in systemic lupus erythematosus: a prospective study. Am J Obstet Gynecol. 1998;179:226-234.
31. Shoenfeld Y. Induction of experimental primary and secondary antiphospholipid syndromes in naive mice. Am J Reprod Immunol. 1992;28:219-221.
32. Fishman P, Falach-Vaknine E, Zigelman R, Bakimer R, Sredni B, Djaldetti M, Shoenfeld Y. Prevention of fetal loss in experimental antiphospholipid syndrome by in vivo administration of recombinant interleukin-3. J Clin Invest. 1993;91:1834-1837.
33. Birkenfeld A, Mukaida T, Minichiello L, Jackson M, Kase NG, Yemini M. Incidence of autoimmune antibodies in failed embryo transfer cycles. Am J Reprod Immunol. 1994;31:65-68.
34. Gleicher N, Pratt D, Dudkiewicz AB. Autoantibodies in in vitro fertilization patients. Fertil Steril. 1992;58:863-865.
35. Sthoeger ZM, Mozes E, Tartakovsky B. Anti-cardiolipin antibodies induce pregnancy failure by impairing embryonic implantation. Proc Natl Acad Sci USA. 1993;90:6464-6467.
36. Oshiro BT, Silver RM, Scott JR, Yu H, Branch DW. Antiphospholipid antibodies and fetal death. Obstet Gynecol. 1996;87:489-493.
37. Branch DW, Andres R, Digre KB, Rote NS, Scott JR. The association of antiphospholipid antibodies with severe preeclampsia. Obstet Gynecol. 1989;73:541-545.
38. Ilbery M, Jones AR, Sampson J. Lupus anticoagulant and HELLP syndrome complicated by placental abruption, hepatic, dermal and adrenal infarction. Aust NZJ Obstet Gynaecol. 1995;35:215-217.
39. Alsulyman OM, Castro MA, Zuckerman E, McGehee W, Goodwin TM. Preeclampsia and liver infarction in early pregnancy associated with the antiphospholipid syndrome. Obstet Gynecol. 1996;88:644-646.
40. Kon SP, Kwan JT, Raftery MJ. Reversible renal failure due to the antiphospholipid antibody syndrome, pre-eclampsia and renal thrombotic microangiopathy. Clin Nephrol 1995;44:271-273.
41. Mor F, Beigel Y, Inbal A, Goren M, Wysenbeek AJ. Hepatic infarction in a patient with the lupus anticoagulant. Arthritis Rheum. 1989;32:491-495.
42. Lima F, Khamashta MA, Buchanan NM, Kerslake S, Hunt BJ, Hughes GR. A study of sixty pregnancies in patients with the antiphospholipid syndrome. Clin Exp Rheumatol. 1996;14:131-136.
43. Navarro F, Dona-Naranjo MA, Villanueva I. Neonatal antiphospholipid syndrome. J Rheumatol. 1997;24:1240-1241.
44. Pollard JK, Scott JR, Branch DW. Outcome of children born to women treated during pregnancy for the antiphospholipid syndrome. Obstet Gynecol. 1992;80:365-368.
45. Kutteh WH. Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone. Am J Obstet Gynecol. 1996;174:1584-1589.
46. Kutteh WH, Ermel LD. A clinical trial for the treatment of antiphospholipid antibody-associated recurrent pregnancy loss with lower dose heparin and aspirin. Am J Reprod Immunol. 1996;35:402-407.
47. Rai R, Cohen H, Dave M, Regan L. Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies. Brit Med J. 1997;314:253-257.
48. Cowchock FS, Reece EA, Balaban D, Branch DW, Plouffe L. Repeated fetal losses associated with antiphospholipid antibodies: a collaborative randomized trial comparing prednisone with low-dose heparin treatment. Am J Obstet Gynecol. 1992;166:1318-1323.
49. Nelson-Piercy C. Review: Heparin-induced osteoporosis in pregnancy. Lupus. 1997;6:500-504.
50. Dahlman TC, Sjoberg HE, Ringertz H. Bone mineral density during long-term prophylaxis with heparin in pregnancy. Am J Obstet Gynecol. 1994;170:1315-1320.
51. Dulitzki M, Pauzner R, Langevitz P, Pras M, Many A, Schiff E. Low-molecular weight heparin during pregnancy and delivery: preliminary experience with 41 pregnancies. Obstet Gynecol. 1996;87:380-383.
52. Pregnancy Loss Study Group. A multicenter, randomized, double-blind pilot study of IVIG therapy during pregnancy in women with antiphospholipid syndrome. Lupus. 1998;7:S196a.