How and how much can Hoechst 33258 cause unwinding in a DNA duplex?

Chemical and Pharmaceutical Bulletin

Volumn 47, Issue 10, 1999, Pages 1363-1368

  Utsuno, Kuniharu ^a   Maeda, Yoshimi ^a   Tsuboi, Masamichi ^a  

^a IWAKI MEISEI UNIVERSITY   (Japan)

Author keywords

Calorimetry; Hoechst 33258; Plasmid; Topoisomer; Topoisomerase I; Topoisomerase II; Unwinding of DNA duplex

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; DNA TOPOISOMERASE (ATP HYDROLYSING); DOUBLE STRANDED DNA;

ARTICLE; BINDING KINETICS; CALORIMETRY; CONCENTRATION RESPONSE; DNA CONFORMATION; DRUG DNA BINDING; DRUG DNA INTERACTION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; FLUORESCENCE ANALYSIS; GEL ELECTROPHORESIS; LIGHT ABSORPTION; PLASMID;

EID: 0032709844     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.47.1363     Document Type: Article

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