Supplementation with magnesium and tocopherol diminishes quinolone-induced chondrotoxicity in immature rats

Drugs

Volumn 58, Issue SUPPL. 2, 1999, Pages 393-394

  Stahlmann, R ^a   Schwabe, R ^a   Pfister, K ^a   Lozo, E ^a   Shakibaei, M ^a   Vormann, J ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; FREE RADICAL; MAGNESIUM; OFLOXACIN; QUINOLONE DERIVATIVE; TOCOPHEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICULAR CARTILAGE; CARTILAGE; CHONDROPATHY; CONFERENCE PAPER; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG TISSUE LEVEL; NONHUMAN; ORAL DRUG ADMINISTRATION; PATHOGENESIS; RAT; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALIA;

EID: 0032708170     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-199958002-00136     Document Type: Conference Paper

References (7)

1. 1. R Stahlmann C Förster M Shakibaei 1995 Magnesium deficiency induces joint cartilage lesions in juvenile rats which are identical to quinolone-induced arthropathy Antimicrob Agents Chemother 39 2013 8 8540708 10.1128/AAC.39.9.2013 1:CAS:528:DyaK2MXnvVygsbY%3D Stahlmann R, Förster C, Shakibaei M, et al. Magnesium deficiency induces joint cartilage lesions in juvenile rats which are identical to quinolone-induced arthropathy. Antimicrob Agents Chemother 1995; 39: 2013–8
2. 2. C Förster K Kociok M Shakibaei 1996 Integrins on joint cartilage chondrocytes and alterations by ofloxacin or magnesium deficiency in immature rats Arch Toxicol 70 261 70 8852696 10.1007/s002040050272 Förster C, Kociok K, Shakibaei M, et al. Integrins on joint cartilage chondrocytes and alterations by ofloxacin or magnesium deficiency in immature rats. Arch Toxicol 1996; 70: 261–70
3. 3. J Vormann C Förster U Zippel 1997 Effects of magnesium deficiency on magnesium and calcium content in bone and cartilage in developing rats in correlation to chondrotoxicity Calcif Tissue Int 61 230 8 9262515 10.1007/s002239900328 1:CAS:528:DyaK2sXlslKht74%3D Vormann J, Förster C, Zippel U, et al. Effects of magnesium deficiency on magnesium and calcium content in bone and cartilage in developing rats in correlation to chondrotoxicity. Calcif Tissue Int 1997; 61: 230–8
4. 4. G Hayem PX Petit M Levacher 1994 Cytofluorometric analysis of chondrotoxicity of fluoroquinolone antimicrobial resistance Antimicrob Agents Chemother 38 243 7 8192451 10.1128/AAC.38.2.243 1:CAS:528:DyaK2cXhvVantrY%3D Hayem G, Petit PX, Levacher M, et al. Cytofluorometric analysis of chondrotoxicity of fluoroquinolone antimicrobial resistance. Antimicrob Agents Chemother 1994; 38: 243–7
5. 5. I Syllm-Rapoport I Strassburger D Grüneberg 1958 Uber den experimentellen Magnesium-Mangel beim Hund Acta Biol Med Germ 1 141 63 13594096 1:CAS:528:DyaF3cXksFCqsw%3D%3D Syllm-Rapoport I, Strassburger I, Grüneberg D, et al. Uber den experimentellen Magnesium-Mangel beim Hund. Acta Biol Med Germ 1958; 1: 141–63
6. 6. R Stahlmann U Zippel C Förster 1998 Chondrotoxicity and toxicokinetics of sparfloxacin in juvenile rats Antimicrob Agents Chemother 42 1470 5 9624496 1:CAS:528:DyaK1cXjs1yru7k%3D Stahlmann R, Zippel U, Förster C, et al. Chondrotoxicity and toxicokinetics of sparfloxacin in juvenile rats. Antimicrob Agents Chemother 1998; 42: 1470–5
7. 7. R Schwabe E Lozo L Baumann-Wilschke 1999 Chondrotoxicity and target tissue kinetics of ofloxacin in immature rats after multiple doses Drugs 58 2 385 7 10.2165/00003495-199958002-00133 1:CAS:528:DyaK1MXntFehu7Y%3D Schwabe R, Lozo E, Baumann-Wilschke L, et al. Chondrotoxicity and target tissue kinetics of ofloxacin in immature rats after multiple doses. Drugs 1999; 58 Suppl. 2: 385–7