Chromatographic resolution, chiroptical characterization and preliminary pharmacological evaluation of the enantiomers of butibufen: A comparison with ibuprofen

Journal of Pharmacy and Pharmacology

Volumn 51, Issue 10, 1999, Pages 1201-1205

  Hoult, J R S ^a   Jackson, B R ^a   Benicka, E ^a   Patel, B K ^a   Hutt, A J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 PROPANOL; ARACHIDONATE 5 LIPOXYGENASE; BUTIBUFEN; CALCIUM IONOPHORE; HEXANE; IBUPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; THROMBOXANE B2; TRIFLUOROACETIC ACID;

ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG SPECIFICITY; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ICOSANOID METABOLISM; LEUKOCYTE; NONHUMAN; RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACIDS; ASCITIC FLUID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; CYCLOOXYGENASE INHIBITORS; EICOSANOIDS; ENZYME INHIBITORS; IBUPROFEN; LEUKOCYTES; MALE; PHENYLBUTYRATES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, WISTAR; STEREOISOMERISM;

EID: 0032706956     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357991776741     Document Type: Article

References (22)

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