Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases

British Journal of Pharmacology

Volumn 122, Issue 3, 1997, Pages 487-492

  Neupert, Werner ^a   Brugger, Roland ^a   Euchenhofer, Christian ^a   Brune, Kay ^a   Geisslinger, Gerd ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Chiral inversion; Coenzyme A thioester; Enantiomers; Ibuprofen; Prostaglandin endoperoxide synthase

Indexed keywords

ACETYLSALICYLIC ACID; HEPARIN; IBUPROFEN; IBUPROFEN DERIVATIVE; LIPOPOLYSACCHARIDE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; THROMBOXANE B2;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG POTENCY; DRUG SAFETY; DRUG SELECTIVITY; ENANTIOMER; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNOBLOTTING; MONOCYTE; NORMAL HUMAN; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; PROTEIN EXPRESSION; THROMBOCYTE;

BLOOD PLATELETS; BLOTTING, WESTERN; COENZYME A; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; ESTERS; HUMANS; IBUPROFEN; ISOENZYMES; MEMBRANE PROTEINS; MONOCYTES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; STEREOISOMERISM; SULFIDES; THROMBOXANE B2;

EID: 0030953302     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701415     Document Type: Article

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