YC-1 potentiates the antiplatelet effect of hydrogen peroxide via sensitization of soluble guanylate cyclase

European Journal of Pharmacology

Volumn 381, Issue 2-3, 1999, Pages 185-191

  Wu, Chin Chung ^a   Kuo, Sheng Chu ^b   Lee, Fang Yu ^c   Teng, Che Ming ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c Yung Shin Pharmaceutical Industry Co Ltd   (Taiwan)

Author keywords

Antiplatelet; Guanylate cyclase, soluble; Hydrogen peroxide; YC 1

Indexed keywords

1 BENZYL 3 (5 HYDROXYMETHYL 2 FURYL)INDAZOLE; 1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; CATALASE; CYCLIC GMP; GUANYLATE CYCLASE; HYDROGEN PEROXIDE; MANNITOL; SUPEROXIDE DISMUTASE;

ARTICLE; DRUG ACTIVITY; DRUG POTENTIATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SENSITIZATION; THROMBOCYTE AGGREGATION INHIBITION;

ANTIOXIDANTS; BLOOD PLATELETS; CATALASE; CYCLIC GMP; GLUCOSE OXIDASE; GLUTATHIONE PEROXIDASE; GUANYLATE CYCLASE; HEMOSTATICS; HUMANS; HYDROGEN PEROXIDE; INDAZOLES; MANNITOL; PLATELET AGGREGATION INHIBITORS; SUPEROXIDE DISMUTASE; THROMBIN;

EID: 0032705227     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00577-4     Document Type: Article

References (33)

1. Aebi H. Catalase in vitro. Methods Enzymol. 105:1984;121-126.
2. Ambrosio G., Golino P., Pascucci I., Rosolowsky M., Campbell W.B., DeClerck F., Tritto I., Chiariello M. Modulation of platelet function by reactive oxygen metabolites. Am. J. Physiol. 267:1994;H308-H318.
3. Ambrosio G., Tritto I., Golino P. Reactive oxygen metabolites and arterial thrombosis. Cardiovasc. Res. 34:1997;445-452.
4. Bolli R., Patel B.S., Jeroudi M.O., Lai E.K., McCay P.B. Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of spin trap alpha-phenyl N-tert-butyl nitrone. J. Clin. Invest. 82:1988;476-485.
5. Born G.V.R. Quantitative investigations into the aggregation of blood platelets. J. Physiol. 162:1962;67-72.
6. Burke T.M., Wolin M.S. Hydrogen peroxide elicits pulmonary arterial relaxation and guanylate cyclase activation. Am. J. Physiol. 252:1987;H721-H732.
7. Canoso R.T., Rodvien R., Scoon K., Levine P.H. Hydrogen peroxide and platelet function. Blood. 43:1974;645-656.
8. Del Principe D., Menichelli A., De Matteis W., Di Corpo M.C., Di Giulio S., Finazzi-Agro' A. Hydrogen peroxide has a role in the aggregation of human platelets. FEBS Lett. 185:1985;142-146.
9. Flohe L., Gunzler W.A. Assays of glutathione peroxidase. Methods Enzymol. 105:1984;114-121.
10. Forde R.C., Fitzgerald D.J. Reactive oxygen species and platelet activation in reperfusion injury. Circulation. 95:1997;787-789.
11. Freedman J.E., Loscalzo J., Benoit S.E., Valeri C.R., Barnard M.R., Michelson A.D. Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis. J. Clin. Invest. 97:1996;979-987.
12. Friebe A., Schultz G., Koesling D. Sensitizing soluble guanylyl cyclase to become a highly CO-sensitive enzyme. EMBO J. 15:1996;6863-6868.
13. Garthwaite J., Southam E., Boulton C.L., Nielsen E.B., Schmidt K., Mayer B. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol. Pharmacol. 48:1995;184-188.
14. Gerzer R., Hamet P., Ross A.H., Lawson J.A., Hardman J.G. Calcium-induced release from platelet membrane of fatty acids that modulate soluble guanylate cyclase. J. Pharmacol. Exp. Ther. 226:1983;180-186.
15. Hwang T.L., Wu C.C., Teng C.M. YC-1 potentiates nitric oxide-induced relaxation in guinea-pig trachea. Br. J. Pharmacol. 1999;. In press.
16. Karniguian A., Legrand Y.J., Caen J.P. Prostaglandins: specific inhibition of platelet adhesion to collagen and relationship with cAMP level. Prostaglandins. 23:1982;437-457.
17. Ko F.N., Wu C.C., Kuo S.C., Lee F.Y., Teng C.M. YC-1, a novel activator of platelet guanylate cyclase. Blood. 84:1994;4226-4233.
18. Leoncini G. N-ethylmaleimide inhibits platelet aggregation and potentiates hydrogen peroxide formation induced by thrombin. Mol. Biol. Int. 34:1994;119-126.
19. Leoncini G., Maresca M., Colao C. Oxidative metabolism of human platelets. Biochem. Int. 25:1991;647-655.
20. Leoncini G., Signorello M.G., Piana A., Carrubba M., Armani U. Hyperactivity and increased hydrogen peroxide formation in platelets of NIDM patients. Thromb. Res. 86:1997;153-160.
21. Mülsch A., Bauersachs J., Schafer A., Stasch J.-P., Kast R., Busse R. Effect of YC-1, an NO-independent, superoxide-sensitive stimulator of soluble guanylyl cyclase, on smooth muscle responsiveness to nitrovasodilators. Br. J. Pharmacol. 120:1997;681-689.
22. Naseem K.M., Bruckdorfer K.R. Hydrogen peroxide at low concentrations strongly enhances the inhibitory effect of nitric oxide on platelets. Biochem. J. 310:1995;149-153.
23. Naseem K.M., Chirico S., Mohammadi B., Bruckdorfer K.R. The synergism of hydrogen peroxide with plasma S-nitrosothiols in the inhibition of platelet activation. Biochem. J. 318:1996;759-766.
24. Pratico D., Iuliano L., Pulcinelli F.M., Bonavita M.S., Gazzaniga P., Violi F. Hydrogen peroxide triggers activation of human platelets selectively exposed to nonaggregating concentrations of arachidonic acid and collagen. J. Lab. Clin. Med. 119:1992;364-370.
25. Russwurm M., Behrends S., Harteneck C., Koesling D. Functional properties of a naturally occurring isoform of soluble guanylate cyclase. Biochem. J. 335:1998;125-130.
26. Schmidt H.H.H.W. NO, CO and OH. Endogenous soluble guanylyl cyclase-activating factors. FEBS Lett. 307:1992;102-107.
27. Teng C.M., Wu C.C., Ko F.N., Lee F.Y., Kuo S.C. YC-1, a NO-independent activator of soluble guanylate cyclase, inhibits platelet-rich thrombosis in mice. Eur. J. Pharmacol. 320:1997;161-166.
28. Wu C.C., Ko F.N., Wu T.S., Teng C.M. Antiplatelet effects of Clausine-D isolated from Clausena excavata. Biochem. Biophys. Acta. 1201:1994;1-6.
29. Wu C.C., Ko F.N., Kuo S.C., Lee F.Y., Teng C.M. YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase. Br. J. Pharmacol. 116:1995;1973-1978.
30. Wu C.C., Ko F.N., Teng C.M. Inhibition of platelet adhesion to collagen by cGMP-elevating agents. Biochem. Biophys. Res. Commun. 231:1997;412-416.
31. Yoshina S., Kuo S.C. Studies on heterocyclic compounds: XXXV. Synthesis of fuo [3,3-C] pyrazole derivatives. (2) Electrophilic substitution of 1,3-diphenylfuro [3,2-C] pyrazole. Yakugaku Zasshi. 98:1978;204-208.
32. Zabel U., Weeger M., La M., Schmidt H.H.H.W. Human soluble guanylate cyclase: functional expression and revised isoenzyme family. Biochem. J. 335:1998;51-57.
33. Zweier J.L., Flaherty J.T., Weisfeldt M.L. Direct measurement of free radical generation following reperfusion of ischemic myocardium. Proc. Natl. Acad. Sci. U.S.A. 84:1987;1404-1407.