Characterization of the central muscarinic cholinoceptors involved in the cholinergic pressor response in anesthetized dogs

European Journal of Pharmacology

Volumn 379, Issue 2-3, 1999, Pages 117-124

  Pelat, Michel ^a   Lazartigues, Eric ^a   Tran, Marie Antoinette ^a   Gharib, Claude ^b   Montastruc, Jean Louis ^a   Montastruc, Paul ^a   Rascol, Olivier ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

Acetylcholine; Blood pressure; Muscarinic receptor; Pirenzepine

Indexed keywords

ACETYLCHOLINE; ATROPINE; CHOLINERGIC RECEPTOR; METHOCTRAMINE; MUSCARINIC M1 RECEPTOR; MUSCARINIC M1 RECEPTOR ANTAGONIST; MUSCARINIC M2 RECEPTOR; MUSCARINIC M2 RECEPTOR ANTAGONIST; MUSCARINIC M3 RECEPTOR; MUSCARINIC M3 RECEPTOR ANTAGONIST; MUSCARINIC RECEPTOR; MUSCARINIC RECEPTOR BLOCKING AGENT; PARA FLUOROHEXAHYDROSILADIFENIDOL; PIRENZEPINE;

ANIMAL EXPERIMENT; ARTICLE; BRADYCARDIA; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOG; DRUG POTENCY; HEART RATE; INTRACEREBRAL DRUG ADMINISTRATION; INTRACISTERNAL DRUG ADMINISTRATION; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RECEPTOR AFFINITY; VASODILATATION;

ACETYLCHOLINE; ANESTHESIA; ANIMALS; ATROPINE; BLOOD PRESSURE; DIAMINES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MUSCARINIC ANTAGONISTS; NOREPINEPHRINE; RECEPTOR, MUSCARINIC M1; RECEPTORS, MUSCARINIC; VASODILATOR AGENTS; VASOPRESSINS;

EID: 0032703796     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00508-7     Document Type: Article

References (30)

1. 2 muscarinic receptors in conscious cats. Brain Res. 677:1995;268-276.
2. Bonner T., Buckley N., Young A., Brown M. Identification of a family of muscarinic acetylcholine receptor genes. Science. 237:1987;527-532.
3. 3 muscarinic receptors of both endothelium-dependent contraction and relaxation to acetylcholine in the aorta of the spontaneously hypertensive rat. Br. J. Pharmacol. 112:1994;519-524.
4. Brefel C., Lazartigues E., Tran M.A., Gauquelin G., Geelen G., Gharib C., Montastruc J.L., Montastruc P., Rascol O. Central cardiovascular effects of acetylcholine in the conscious dog. Br. J. Pharmacol. 116:1995;2175-2182.
5. Brezenoff H.E., Giuliano R. Cardiovascular control by cholinergic mechanisms in the central nervous system. Ann. Rev. Pharmacol. Toxicol. 22:1982;341-381.
6. 2 muscarinic receptors lowers blood pressure in spontaneously hypertensive rats. Pharmacology. 36:1988;101-105.
7. Buccafusco J.J. The role of central cholinergic neurons in the regulation of blood pressure and in experimental hypertension. Pharmacol. Rev. 48:1996;179-211.
8. Buccafusco J.J., Brezenoff H.E. Pharmacological study of a cholinergic mechanism within the rat posterior hypothalamic nucleus which mediates a hypertensive response. Brain Res. 165:1979;295-310.
9. Caulfield M. Muscarinic receptors - characterization, coupling and function. Pharmacol. Ther. 58:1993;319-379.
10. Dorje F., Friebe T., Tacke R., Mutschler E., Lambrecht G. Novel pharmacological profile of muscarinic receptors mediating contraction of the guinea-pig uterus. Naunyn Schmiedeberg's Arch. Pharmacol. 342:1990;284-289.
11. Eglen R.M., Watson N. Selective muscarinic receptor agonists and antagonists. Pharmacol. Toxicol. 78:1996;59-68.
12. Eglen R.M., Michel A., Montgomery W. The interaction of parafluorohexahydrosiladifenidol at muscarinic receptors in vitro. Br. J. Pharmacol. 99:1990;637-642.
13. 1 muscarinic antagonist. Life Sci. 57:1995;1853-1859.
14. Hosey M. Diversity of structure, signaling and regulation within the family of muscarinic cholinergic receptors. FASEB J. 6:1992;845-852.
15. Krstic M.K., Djurkovic D. Cardiovascular response to intracerebroventricular administration of acetylcholine in rats. Neuropharmacology. 17:1978;341-347.
16. Kurtel H., Yegen B., Dedeoglu A., Ulusoy N., Oktay S. Muscarinic receptor subtypes of guinea-pig gallbladder smooth muscle. Arch. Int. Pharmacodyn. Ther. 308:1990;39-46.
17. 4 binding sites in rabbit lung, chicken heart and NG 108-15 cells. Mol. Pharmacol. 38:1990;805-815.
18. Lazartigues E., Tellioglu T., Brefel-Courbon C., Tran M., Montastruc J., Rascol O. Physostigmine-induced pressor response in normotensive and spontaneously hypertensive rats. Fundam. Clin. Pharmacol. 12:1998;340.
19. Lazartigues E., Freslon J.L., Tellioglu T., Brefel-Courbon C., Pelat M., Tran M., Montastruc J.L., Rascol O. Pressor and bradycardic effects of tacrine and other acetylcholinesterase inhibitors in the rat. Eur. J. Pharmacol. 361:1998;61-71.
20. 3 receptor. Eur. J. Pharmacol. 215:1992;83-91.
21. Michel A., Delmendo R., Stefanich E., Whiting R. Binding characteristics of the muscarinic receptor subtype of the NG 108-15 cell line. Naunyn Schmiedeberg's Arch. Pharmacol. 340:1989;62-67.
22. 2 cholinoceptors involved in cholinergic hypertension. Eur. J. Pharmacol. 250:1993;349-354.
23. Rascol O., Montastruc J.L., Gauquelin G., Tran M.A., Geelen G., Gharib C., Montastruc P. Cardiovascular effects of central injection of acetylcholine in anaesthetized dogs: a role for vasopressin release. Br. J. Pharmacol. 100:1990;471-476.
24. Rossi N., Schrier R. Role of arginine vasopressin in regulation of systemic arterial pressure. Ann. Rev. Med. 37:1986;13-20.
25. Suh T., Wang C., LIM R. Effects of intracisternal injections of acetylcholine. Proc. Soc. Exp. Biol. Med. 32:1935;1410.
26. Tietje K., Goldman P., Nathanson N. Cloning and functional analysis of a gene encoding a novel muscarinic acetylcholine receptor expressed in chick heart and brain. J. Biol. Chem. 265:1990;2828-2834.
27. Van Zwieten P., Hendricks, Pfaffendorf M., Bruning T., Chang P.C. The parasympathetic system and its muscarinic receptors in hypertensive disease. J. Hypertens. 13:1995;1079-1090.
28. 4) in rat forebrain. Mol. Pharmacol. 38:1990;267-273.
29. Wei J., Milici A., Buccafusco J. Alterations in the expression of the genes encoding specific muscarinic receptor subtypes in the hypothalamus of spontaneously hypertensive rats. Circ. Res. 76:1995;142-147.
30. 2 muscarinic receptors in the posterior hypothalamus in the pressor response to intracerebroventricularly-injected neostigmine. Neuropharmacology. 27:1988;1061-1065.