Etomidate dose-response on somatosensory and transcranial magnetic induced spinal motor evoked potentials in primates

Neurological Research

Volumn 21, Issue 8, 1999, Pages 714-720

  Ghaly, Ramsis F ^a,b   Lee, James J ^b   Ham, Jong H ^b   Stone, James L ^b   George, Sumana ^b   Raccforte, Peter ^b  

^a Chicago Institute of Neurosurgery and Neuroresearch   (United States)

^b Jr Hospital of Cook County   (United States)

Author keywords

Etomidate; Monitoring; Motor evoked potentials; Primates; Somatosensory evoked potentials; Transcranial magnetic stimulation

Indexed keywords

ETOMIDATE; METHOHEXITAL; NITROUS OXIDE PLUS OXYGEN; RINGER LACTATE SOLUTION; VECURONIUM;

ANESTHESIA; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ELECTROENCEPHALOGRAPHY; EVOKED MUSCLE RESPONSE; EVOKED SOMATOSENSORY RESPONSE; EVOKED SPINAL CORD RESPONSE; INHALATIONAL DRUG ADMINISTRATION; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MONITORING; NEUROPHYSIOLOGY; NEUROPROTECTION; NONHUMAN; POSTERIOR TIBIAL NERVE; PRIMATE; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 0032701783     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1080/01616412.1999.11741003     Document Type: Article

References (34)

1. Amassian VE, Stewart M, Quick GJ, Rosenthal RL. Physiological basis of motor effects of a transient stimulus to cerebral cortex. Neurosurgery 1987; 20: 74-93
2. Burke D, Hicks RG. Surgical monitoring of motor pathways. J Clin Neurophysiol 1998; 15: 194-205
3. Edmonds HL, Paloheimo MPJ, Backman MH, Johnson JR, Hold RT, Shield CB. Transcranial magnetic motor evoked potentials (tcMMEP) for functional monitoring of motor pathways during scoliosis surgery. Spine 1989; 14: 683-686
4. Lee WY, Hou WY, Yang LH, Lin SM. Intraoperative monitoring of motor function by magnetic motor evoked potentials. Neurosurgery 1995; 36: 493-500
5. Bernhard CG, Bohm E. Cortical representation and functional significance of the cortico-motoneuronal system. Arch Neurol Psychiatry 1954; 72: 473-502
6. Ghaly RF, Stone JL, Lee JJ, Ham JH, Levy WJ. Monitoring spinal cord motor and somatosensory evoked potentials in anesthetized primates. Neurol Res 1999; 21: 359-367
7. Ghaly RF, Stone JL, Levy WJ. A protocol for intraoperative somatosensory and motor evoked potentials (MEP) recordings. J Neurosurg Anesthesiol 1992; 4: 68-69
8. Ghaly RF, Stone JL, Levy WJ, Kartha R, Brunner EB, Roccaforte P, Aldrete JA. The effect of an anesthetic induction dose of midazolam on motor potentials evoked by transcranial magnetic stimulation in the monkey. J Neurosurg Anesthesiol 1991; 3: 20-27
9. Ghaly RF, Stone JL, Aldrete JA. Incremental dose-effect of ketamine on transcranial magnetic motor evoked potential: A primate study. J Neurosurg Anesthesiol 1990; 1: 79-85
10. Ghaly RF, Stone JL, Levy WJ, Aldrete JA, Kartha R. The effect of nitrous oxide on transcranial magnetic-induced electromyographic responses in the monkey. J Neurosurg Anesthesiol 1990; 2: 175-181
11. Ghaly RF, Stone JL, Levy WJ, Roccaforte P, Brunner EB. The effect of etomidate on transcranial magnetic-induced motor evoked potentials in the monkey. Neurosurgery 1990; 27: 936-942
12. Ghaly RF, Stone JL, Levy WJ, Kartha R, Brunner EA, Aldrete JA, Lege R. The effect of neuroleptanalgesia (Dropenchol-Fentanyl) on motor potentials evoked by transcranial magnetic stimulation in the monkey. J Neurosurg Anesthesiol 1991; 3: 117-123
13. Kalkman CJ, Drummond JC, Ribberink AA, Patel PM, Sano T, Bickford RG. Effects of propofol, etomidate, midazolam, and fentanyl on motor evoked responses to transcranial electrical or magnetic stimulation in humans. Anesthesiology 1992; 76: 502-509
14. Schmid UD, Boll J, Liechti S, Schmid S, Hess CW. Influence of some anesthetic agents on muscle responses to transcranial magnetic cortex stimulation: A pilot study in humans. Neurosurgery 1992; 30: 85-92
15. Stone JL, Ghaly RF, Levy WJ, Kartha R, Krinsky L, Roccafort P. A comparative analysis of enflurane anesthesia on primate motor and somatosensory evoked potentials. Electroenceph Clin Neurophysiol 1992; 84: 180-187
16. Zenter J, Albrect T, Heuser D. Influence of halothane, enflurane, and isoflurane on motor evoked potentials. Neurosurgery 1992; 31: 298-305
17. Taniguchi M, Nadstawedk J, Iangenbach U, Bremer F, Schramm J. Effects of four intravenous anesthetic agents on motor evoked potentials elicited by magnetic transcranial stimulation. Neurosurgery 1993; 33: 407-415
18. Humphrey DR, Corrie WS. Properties of the pyramidal tract neuron system within a functionally defined subregion of primate motor cortex. J Neurophysiology 1978; 41: 216-243
19. Katayama Y, Tsubokawa T, Sugitani M, Maejima S, Hirayama T. Assessment of spinal cord injury with multimodality evoked spinal cord potentials: Part 1. Localization of lesions in experimental spinal cord injury. Neuro-Orthopedics 1986; 1: 130-141
20. Konrad PE, Tacker WA, Levy WJ, Reedy P, Cook J, Geddes LA. Motor evoked potentials in the dog. Effects of global ischemia on spinal cord and peripheral nerve signals. Neurosurgery 1987; 20: 117-124
21. Levy WJ, McCaffrey M, Haghighi S. Motor evoked potential as a predictor of recovery in chronic spinal cord injury. Neurosurgery 1987; 20: 138-142
22. Lorente de No R. The cerebral cortex arthitecture, intracortical connections and motor projections. In: Fulton JF, ed. Physiology of the Nervous System, New York: Oxford University Press, 1938: pp. 291-325
23. Patton HD, Amassian VE. Single- and multiple-unit analysis of cortical state of pyramidal tract activation. J Neurophysiology 1954; 17: 345-363
24. Ghoneim MM, Yamada T. Etomidate: A clinical and electroencephalographic comparison with thiopental. Anesth Analg 1977; 56: 479-485
25. Milde LN, Milde JH, Michenfelder JD. Cerebral functional, metabolic and hemodynamic effects of etomidate in dogs. Anesthesiology 1985; 63: 371-377
26. Batjer HH. Cerebral protective effects of etomidate: Experimental and clinical aspects. Cerebrovasc Brain Metab 1993; 5: 17-32
27. Batjer HH, Frankfurt AI, Purdy PD, Smith SS, Samson DS. Use of etomidate, temporary arterial occlusion, and intraoperative angiography in surgical treatment of large and giant cerebral aneurysms. J Neurosurg 1988; 68: 234-240
28. Meinck HM, Mohlenhof O, Kettler D. Neurophysiological effects of etomidate, a new short-acting hypnotic. Electroencephalogr Clin Neurophysiol 1980; 50: 515-522
29. Moss E, Powell D, Gibson RM, McDowall G. Effect of etomidate on intracranial pressure and cerebral perfusion pressure. Br J Anaesth 1979; 51: 347-352
30. Prior JGL, Hinds CJ, Williams J, Prior PF. The use of etomidate in the management of severe head injury. Intensive Care Med 1983; 9: 313-320
31. Renou AM, Vernheit J, Macrez P, Constant P, Billerey J, Khadaroo MY, Caille JM. Cerebral blood flow metabolism during etomidate anesthesia in man. Br J Anesth 1978; 50: 1047-1051
32. McPherson RW, Sell B, Traystman RJ. Effects of thiopental, fentanyl, and etomidate on upper extremity somatosensory evoked potentials in humans. Anesthesiology 1986; 65: 584-589
33. Samra SK, Sorkin SL. Enhancement of somatosensory evoked potentials by etomidate: Investigation of its site of action in cats. Anesth Analg 1990; 70: S345 (Abstract)
34. Sloan TB, Ronai AK, Toleikis RJ, Koht A. Improvement of intraoperative somatosensory evoked potentials by etomidate. Anesth Analg 1988; 67: 582-585