Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-Substituted-6-amino-5-phenylbicyclo[2.2.2]octanes

Journal of Medicinal Chemistry

Volumn 42, Issue 23, 1999, Pages 4836-4843

  Javanmard, Sahar ^a   Deutsch, Howard M ^a   Collard, David M ^a   Kuhar, Michael J ^b   Schweri, Margaret M ^c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY   (United States)

^c MERCER UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYCLOHEXENONE; 3BETA (4 FLUOROPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; BICYCLO COMPOUND; COCAINE; DOPAMINE; NISOXETINE; NORADRENALIN; PAROXETINE; PHENYL GROUP; SEROTONIN;

ARTICLE; BINDING AFFINITY; DIASTEREOISOMER; DRUG BINDING; DRUG SYNTHESIS; DRUG TRANSPORT; LIGAND BINDING; MOLECULAR MODEL;

ANIMALS; BENZOATES; BICYCLO COMPOUNDS; BINDING, COMPETITIVE; BRAIN; CARRIER PROTEINS; CENTRAL NERVOUS SYSTEM STIMULANTS; COCAINE; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; NERVE TISSUE PROTEINS; NOREPINEPHRINE; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SYMPORTERS;

EID: 0032701144     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990306k     Document Type: Article

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