Lack of effect of caffeine post-treatment on X-ray-induced chromosomal aberrations in Werner's syndrome lymphoblastoid cell lines: A preliminary report

International Journal of Radiation Biology

Volumn 75, Issue 11, 1999, Pages 1349-1355

  Franchitto, A ^a   Proietti De Santis, L ^a   Pichierri, P ^a   Mosesso, P ^a   Palitti, F ^a  

^a UNIVERSITY OF TUSCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; HYDROXYUREA;

ARTICLE; CELL CYCLE G2 PHASE; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; PRIORITY JOURNAL; WEGENER GRANULOMATOSIS; X IRRADIATION;

EID: 0032698302     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530099139223     Document Type: Article

References (33)

1. 2 radiosensitivity of cells derived from cancer-prone individuals. Mutation Research, 328, 83-90.
2. DEKNUDT, G., VERELLEN-DUMOULIN, C. and LEONARD, A., 1985, Mutagens sensitivity in the repair process of the lymphocytes in the Werner syndrome. Compte Rendus. De Royal. Seances Societes De Biologie et Philosophie, 179, 518-521.
3. EVANS, H.J. and SCOTT, D., 1969, The induction of chromosomal aberrations by nitrogen mustard and its dependence on DNA synthesis. Proceedings of the Royal Society of London B, 173, 491-512.
4. FRANCHITTO, A., PICHIERRI, P., MOSESSO, P. and PALITTI, F., 1998, Caffeine effect on the mitotic delay induced by G2 treatment with UVC or mitomycin-G. Mutagenesis, 13, 499-505.
5. FUKUCHI, K., MARTIN, G. M. and MONNAT, R. J., 1989, Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proceedings of National Academy Science USA, 86, 5893-5897.
6. GANGLOFF, S., MCDONALD, J. P., BENDIXEN, C., ARTHUR, L. and ROTHSTEIN, R., 1994, The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase. Molecular and Cellular Biology, 14, 8391-8398.
7. GEBHART, E., BAUER, R., RAUB, U., SCHINZEL, M., RUPRECHT, K. W. and JONAS, J. B., 1988, Spontaneous and induced chromosome instability in Werner syndrome. Human Genetics, 80, 135-139.
8. GRAY, M. D., SHEN, J., KAMATH-LOEB, A. S., BLANK, A., SOPHER, B. L., MARTIN, G. M., OSHIMA, J. and LOEB, L. A., 1997, The Werner syndrome protein is a DNA helicase. Nature Genetics, 17, 100-103.
9. HAIN, J., JAUSSI, R. and WÜRGLER, F. E., 1991, Effects of ionizing radiation and caffeine treatment on cyclin dependent kinase complexes in V79 hamster cells. Cell Signalling, 6, 539-550.
10. HANSSON, K., PALITTI, F., KIHLMAN, B. A. and KARLSSON, M. B., 1982, Potentiation of X-ray-and Streptemogrin-induced chromosomal aberrations in human lymphocytes by post-treatments with hydroxyurea and caffeine. Hereditas, 97, 51-58.
11. HANSSON, K., NATARAJAN, A. T. and KIHLMAN, B. A., 1984, Effect of caffeine in G2 on X-ray-induced chromosomal aberrations and mitotic inhibition in ataxia telangectasia fibroblast and lymphoblastoid cell. Human Genetics, 67, 329-335.
12. HOEHN, H., BRYANT, K. A., NOEWOOD, H. B. and MARTIN, G. M., 1975, Variegated translocation mosaicisrn in human skin fibroblast cultures. Cytogenetics and Cell Genetics, 15, 282-298.
13. HRABKO, R. P., MILGROM, H. and SCHWARTZ, R. A., 1982, Werner's syndrome with associated with malignant neoplasms. Archives in Dermatology, 118, 106-108.
14. KIHLMAN, B. A. and NATARAJAN, A. T., 1984, Potentiation of chromosomal alterations by inhibitors of DNA repair. In DNA Repair and its Inhibition, edited by A. Collins, R. T. Johnson and S. Downes (TRL: Oxford), pp. 319-339.
15. KIHLMAN, B. A., HANSSON, K., PALITTI, F., ANDERSSON, H. C. and HARTLEY-ASP, B., 1982a, Potentiation of induced chromatid-type aberrations by hydroxyurca and caffeine in G2. Progress in Mutation Research, 4, 11-24.
16. KIHLMAN, B. A., HANSSON, K. and ANDERSSON, H. C., 1982b, The effects of post-treatments with caffeine during S and G2 on the frequencies of chromosomal aberrations induced by thiotepa in root tips of Vicia faba and in human lymphocytes in vitro. Mutation Research, 104, 323-330.
17. LINK, C. J., EVANS, M. K., COOK, J. A., MULDOON, R., STEVSNER, T. and BOHR, V. A., 1995, Caffeine inhibits gene-specific repair of UV-induced DNA damage in hamster cells and human xeroderma pigmentosum group G cells. Carcinogenesis, 16, 1149-1155.
18. LOHMAN, T. M., 1993, Helicase-catalyzed DNA unwinding. Journal of Biological Chemistry, 268, 2269-2272.
19. NATARAJAN, A. T., OBE, G. and DULOUT, F. N., 1980, The effect of caffeine post treatment on X-ray-induced chromosomal aberrations in human blood lymphocytes in vitro. Human Genetics, 54, 183-9.
20. NATARAJAN, A. T., MEIJERS, M. and RIJN, J. L. S., 1982, Individual variability of human cells in induction of chromosomal alteration by mutagens. In Mutagens in Our Environment, edited by M. Sorsa and H. Vainio (New York: Liss), pp. 75-88.
21. OSHIMA, J., Yu, C. E., PIUSSAN, C., KLEIN, G., JABKOWSKI, J., BALCI, S., MIKI, T., NAKURA, J., OGIHARA, T., ELLS, J., SMITH, M., MELARAGNO, M. I., FRACCARO, M., SCAPPATICCI, S., MATTHEWS, J., OUAIS, S., JARZEBOWICZ, A., SCHELLENBERG, G. D. and MARTIN, G. M., 1996, Homozygous and compound heterozygous mutations at the Werner syndrome locus. Human Molecular Genetics, 5, 1909-1913.
22. PAINTER, R. B. and YOUNG, B. R., 1980, Radiosensitivity in ataxia-telangiectasia: a new explanation. Proceedings of National Academy Science USA, 77, 7315-7317.
23. PALITTI, F., PICHIERRI, P., FRANCHITTO, A., PROIETTI DE SANTIS, L. and MOSESSO, P., 1999, Chromosome radiosensitivity in human G2 lymphocytes and cell cycle progression. International Journal of Radiation Biology, 75, 621-627.
24. SALK, D., 1982, A review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations. Human Genetics, 62, 1-15.
25. SAVAGE, J. R., 1976, Classification and relationships of induced chromosomal structural changes. Journal of Medical Genetics, 13, 103-122.
26. 2-phase lymphocytes as an indicator of cancer predisposition. Radiation Research, 145, 3 16, 926-932.
27. SELBY, C. P. and SANCAR, A., 1990, Molecular mechanism of DNA repair inhibition by caffeine. Proceedings of National Academy Science USA, 87, 3522-3525.
28. SHIN, G. G., STRAYER, J., WAINI, M. A. and SNAPKA, R. M., 1990, Rapid evaluation of topoisomerase inhibitors: caffeine inhibition of topoisomerases in vivo. Teratogenisis Carcinogenesis and Mutagenesis, 10, 41-52.
29. STEFANINI, M., SCAPPATICCI, S., LAGOMARSINI, P., BORRONI, G., BERARDESCA, E., NUZZO, F., 1989, Chromosome instability in lymphocytes from patients with Werner's syndrome is not associated with DNA repair defects. Mutation Research, 219, 179-185.
30. STURELID, S. and KIHLMAN, B. A., 1978, The temperature and time factors in caffeine potentiation of chemically induced chromosomal aberrations in root tips of Vicia faba. Hereditas, 88, 27-83.
31. WATT, P. M., LUIS, E. J., BORTS, R. H. and HICKSON, I. D., 1995, Sgs1: a cukaryotic homolog of E. coli RecQ that interact with topoisomerase II in vivo and is required for faithful chromosome segregation. Cell, 81, 253-260.
32. YU, C. E., OSHIMA, J., FU, Y. H., WIJSMAN, E. M., HISAMA, F., ALISCH, R., MATTHEWS, S., NAKURA, J., MIKI, T., OUAIS, S., MARTIN, G. M., MULLIGAN, J. and SCHELLENBERG, G. D., 1996, Positional cloning of the Werner's syndrome gene. Science, 272, 258-262.
33. ZAMPETTI-BOSSELER, F. and SCOTT, D., 1985, The effect of caffeine on X-ray-induced mitotic delay in normal human and ataxia-telangectasia fibroblasts. Mutation Research, 143, 251-256.