Are inhaled glucocorticosteroids effective in chronic obstructive pulmonary disease?

American Journal of Respiratory and Critical Care Medicine

Volumn 160, Issue 5 II, 1999, Pages

  Postma, Dirkje S ^a   Kerstjens, Huib A M ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID;

AIRWAY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONFERENCE PAPER; CORTICOSTEROID THERAPY; DRUG EFFICACY; FORCED EXPIRATORY VOLUME; HEALTH STATUS; HUMAN; INFLAMMATION; INHALATIONAL DRUG ADMINISTRATION; LUNG FUNCTION; LUNG PARENCHYMA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

EID: 0032697761     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.160.supplement_1.16     Document Type: Conference Paper

References (48)

1. Murray, C. J., and A. D. Lopez. 1997. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study [see comments]. Lancet 349:1498-1504.
2. Anthonisen, N. R. 1995. Prognosis in chronic obstructive pulmonary disease. Eur. Respir. Rev. 531:310-314.
3. Postma, D. S. 1998. When can an exacerbation of COPD be treated at home? [Comment]. Lancet 351:1827-1828.
4. Wijkstra, P. J., and P. W. Jones. 1998. Quality of life in patients with chronic obstructive pulmonary disease. Eur. Respir. Monogr. 7:235-246.
5. Saetta, M., W. Timens, and P. K. Jeffery. 1998. Pathology. Eur. Respir. Monogr. 7:92-102.
6. Hogg, J. C., P. T. Macklem, and W. M. Thurlbeck. 1968. Site and nature of airway obstruction in chronic obstructive lung disease. N. Engl. J. Med. 278:1355-1360.
7. O'Shaughnessy, T. C., T. W. Ansari, N. C. Barnes, and P. K. Jeffery. 1997. Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8 + T lymphocytes with FEVI. Am. J. Respir. Crit. Care Med. 155:852-857.
8. Jeffery, P. K. 1997. Pathology of asthma and COPD. Eur. Respir. Rev. 7(43): 111-118.
9. Saetta, M. 1997. Central airways inflammation in the development of COPD. Eur. Respir. Rev. 7(43):109-110.
10. Pesci, A., G. A. Rossi, G. Bertorelli, A. Aufiero, P. Zanon, and D. Olivieri. 1994. Mast cells in the airway lumen and bronchial mucosa of patients with chronic bronchitis. Am. J. Respir. Crit. Care Med. 149:1311-1316.
11. Thompson, A. B., D. Daughton, R. A. Robbins, M. A. Ghafouri, M. Oehlerking, and S. I. Rennard, 1989. Intraluminal airway inflammation in chronic bronchitis: characterization and correlation with clinical parameters. Am. Rev. Respir. Dis. 140:1527-1537.
12. Stanescu, D., A. Sanna, C. Veriter, S. Kostianev, P. G. Calegani, L. M. Fabbri, and P. Maestrelli. 1996. Airways obstruction, chronic expectoration, and rapid decline of FEVI in smokers are associated with increased levels of sputum neutrophils. Thorax 51:267-271.
13. Chilvers, E. R., A. G. Rossi, J. Murray, and C. Haslett. 1998. Regulation of granulocyte apoptosis and implications for anti-inflammatory therapy [Editorial]. Thorax 53:533-534.
14. Thompson, A. B., M. B. Mueller, A. J. Heires, T. L. Bohling, D. Daughton, S. W. Yancey, R. S. Sykes, and S. I. Rennard. 1992. Aerosolized beclomethasone in chronic bronchitis: improved pulmonary function and diminished airway inflammation. Am. Rev. Respir. Dis. 146:389-395.
15. Llewellyn-Jones, C. G., T. A. J. Harris, and R. A. Stockley. 1996. Effects of fluticasone propionate on sputum of patients with chronic bronchitis and emphysema. Am. J. Respir. Crit. Care Med. 153:616-621.
16. Confalonieri, M., E. Mainardi, P. R. Della, S. Bernorio, L. Gandola, B. Beghe, and A. Spanevello. 1998. Inhaled corticosteroids reduce neutrophilic bronchial inflammation in patients with chronic obstructive pulmonary disease. Thorax 53:583-585.
17. Keatings, V. M., A. Jatakanon, Y. M. Worsdell, and P. J. Barnes. 1997. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am. J. Respir. Crit. Care Med. 155:542-548.
18. Chanez, P., A. M. Vignola, T. O'Shaugnessy, I. Enander, D. Li, P. K. Jeffery, and J. Bousquet. 1997. Corticosteroid reversibility in COPD is related to features of asthma. Am. J. Respir. Crit. Care Med. 155:1529-1534.
19. Pizzichini, E., M. M. Pizzichini, P. Gibson, K. Parameswaran, G. J. Gleich, L. Berman, J. Dolovich, and F. E. Hargreave. 1998. Sputum cosinophilia predicts benefit from prednisone in smokers with chronic obstructive bronchitis. Am. J. Respir. Crit. Care Med. 158:1511-1517.
20. Postma, D. S., T. E. J. Renkema, and G. H. Köter, 1990. Effects of corticosteroids in "chronic bronchitis" and "chronic obstructive airway disease." Agents Actions Suppl. 30:41-57.
21. Callahan, C. M., R. S. Dittus, and B. P. Katz, 1991. Oral corticosteroid therapy for patients with stable chronic obstructive pulmonary disease: a meta-analysis. Ann. Intern. Med. 114:216-223.
22. Weir, D. C., R. J. Gove, R. S. Roberts, P. S. Burge, and A. S. Robertson. 1990. Time course of response to oral and inhaled corticosteroids in non-asthmatic chronic airflow obstruction. Thorax 45:118-121.
23. Weir, D. C., and P. S. Burge. 1993. Effects of high dose inhaled beclomethasone dipropionate, 750 micrograms and 1500 micrograms twice daily, and 40 mg per day oral prednisolone on lung function, symptoms, and bronchial hyperresponsiveness in patients with non-asthmatic chronic airflow obstruction. Thorax 48:309-316.
24. Wempe, J. B., D. S. Postma, N. Breederveld, D. Alting-Hebing, T. W. van der Mark, and G. H. Koëter. 1992. Separate and combined effects of corticosteroids and bronchodilators on airflow obstruction and airway hyperresponsiveness in asthma. J. Allergy Clin. Immunol. 89:679-687.
25. Wempe, J. B., D. S. Postma, N. Breederveld, E. Kort, T. W. van der Mark, and G. H. Koëter. 1992. Effects of corticosteroids on bronchodilator action in chronic obstructive lung disease. Thorax 47:616-621.
26. Weir, D. C., R. I. Gove, A. S. Robertson, and P. S. Burge. 1991. Response to corticosteroids in chronic airflow obstruction: relationship to emphysema and airway collapse. Eur. Respir. J. 4:1185-1190.
27. Wood-Baker, R., and E. H. Walters. 1999. Corticosteroids for treating acute exacerbations of chronic obstructive pulmonary disease. Cochrane Library (1).
28. Thompson, W. H., C. P. Nielson, P. Carvalho, N. B. Charan, and J. J. Crowley. 1996. Controlled trial of oral prednisone in outpatients with acute COPD exacerbation. Am. J. Respir. Crit. Care Med. 154:407-412.
29. Postma, D. S., E. J. Steenhuis, L. T. van der Weele, and H. J. Sluiter. 1985. Severe chronic airflow obstruction: can corticosteroids slow down progression? Eur. J. Respir. Dis. 67:56-64.
30. Postma, D. S., I. Peters, E. J. Steenhuis, and H. J. Sluiter. 1988. Moderately severe chronic airflow obstruction: can corticosteroids slow down obstruction? Eur. Respir. J. 1:22-26.
31. Auffarth, B., D. S. Postma, J. G. R. de Monchy, T. W. van der Mark, M. Boorsma, and G. H. Koëter. 1991. Effects of inhaled budesonide on spirometric values, reversibility, airway responsiveness, and cough threshold in smokers with chronic obstructive lung disease. Thorax 46:372-377.
32. Engel, T., J. H. Heinig, O. Madsen, M. Hansen, and E. R. Weeke. 1989. A trial of inhaled budesonide on airway responsiveness in smokers with chronic bronchitis. Eur. Respir. J. 2:935-939.
33. Robertson, A. S., R. I. Gove, G. A. Wieland, and P. S. Burge. 1986. A double-blind comparison of oral prednisolone 40 mg/day with inhaled belomethasone dipropionate 1500 mg/day in patients with adult onset chronic obstructive airways disease. Eur. J. Respir. Dis. 69(Suppl. 146):565-569.
34. Rutgers, S. R., G. H. Koeter, T. W. van der Mark, and D. S. Postma. 1998. Short-term treatment with budesonide does not improve hyperresponsiveness to adenosine 5′-monophosphate in COPD. Am. J. Respir. Crit. Care Med. 157:880-886.
35. Watson, A., T. K. Lim, H. Joyce, and N. B. Pride. 1992. Failure of inhaled corticosteroids to modify bronchoconstrictor or bronchodilator responsiveness in middle-aged smokers with mild airflow obstruction. Chest 101:350-355.
36. Weiner, P., M. Weiner, Y. Azgad, and D. Zamir. 1995. Inhaled budesonide therapy for patients with stable COPD. Chest 108:1568-1571.
37. Weir, D. C., R. I. Gove, A. S. Robertson, and P. S. Burge. 1990. Corticosteroid trials in non-asthmatic chronic airflow obstruction: a comparison of oral prednisolone and inhaled beclomethasone dipropionate. Thorax 45:112-117.
38. Wesseling, G. J., M. Quaedvlieg, and E. F. Wouters. 1991. Inhaled budesonide in chronic bronchitis: effects on respiratory impedance. Eur. Respir. J. 4:1101-1105.
39. Kerstjens, H. A. M., P. L. P. Brand, M. D. Hughes, N. J. Robinson, D. S. Postma, H. J. Sluiter, E. R. Bleecker, P. N. R. Dekhuijzen, P. M. de Jong, H. J. J. Mengelers, S. E. Overbeck, D. F. M. E. Schoonbrood, and the Dutch CNSLD Study Group. 1992. A comparison of bronchodilalor therapy with or without inhaled corticosteroid therapy in obstructive airways disease. N. Engl. J. Med. 327:1413-1419.
40. Renkema, T. E. J., J. P. Schouten, G. H. Koëter, and D. S. Postma, 1996, Effects of long-term treatment with corticosteroids in COPD. Chest 109:1156-1162.
41. Derenne, J.-P. 1995. Effects of high dose inhaled beclomethasone on the rate of decline in FF.V1 in patients with chronic obstructive pulmonary disease: results of a 2 years multicentric study (abstract). Am. J. Respir. Crit. Care Med. 151:A463.
42. van Grunsven, P. M., C. P. van Schayck, J. P. Derenne, H. A. M. Kerstjens, T. E. J. Renkema, D. S. Postma, T. Similowski, R. P. Akkermans, P. C. M. Pasker-de Jong, P. N. R. Dekhuijzen, C. L. A. van Herwaarden, and C. van Weel. 1999. Long term effects of inhaled corticosteroids in chronic obstructive pulmonary disease: a meta-analysis. Thorax 54:7-14.
43. Paggiaro, P. L., R. Dahle, I. Bakran, L. Frith, K. Hollingworth, and J. Efthimou. 1998. Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease. Lancet 351:773-780.
44. Bourbeau, J., M. Y. Rouleau, and S. Boucher. 1998. Randomised controlled trial of inhaled corticosteroids in patients with chronic obstructive pulmonary disease. Thorax 53:477-482.
45. Pauwels, R. A., C. G. Lofdahl, N. B. Pride, D. S. Postma, L. A. Laitinen, and S. V. Ohlsson. 1992. European Respiratory Society study on chronic obstructive pulmonary disease (EUROSCOP): hypothesis and design. Eur. Respir. J. 5:1254-1261.
46. Burge, P. S., and P. Calverley. 1994. Inhaled steroids in obstructive lung disease in Europe, the ISOLDE trial: protocol, and progress (abstract). Am. J. Respir. Crit. Care Med. 149:A312.
47. Vestbo, J., P. Lange, T. Sorensen, C. Gronlund, and K. Viskum. 1995. The Copenhagen City Lung Study - a clinical trial of inhaled corticosteroids in COPD: design and progress (abstract). Am. J. Respir. Crit. Care Med. 151:A466.
48. Dompeling, E., C. P. van Schayck, J. Molerna, H. Folgering, P. M. van Grunsven, and C. van Weel. 1992. Inhaled beclomethasone improves the course of asthma and COPD. Eur. Respir. J. 5:945-952.