Preclinical toxicity study of intrathecal administration of the pain relievers dextrorphan, dextromethorphan, and memantine in the sheep model

Neuromodulation

Volumn 2, Issue 4, 1999, Pages 230-240

  Hassenbusch, Samuel J ^a   Satterfield, William C ^a,b   Gradert, Tamara Lee ^a   Binhazim, Awadh W ^a,b   Ahad, Gabi ^a   Mokhtarzadeh, Maryam ^a   Schapiro, Steven J ^a,b   Payne, Richard ^a,b,c  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Continuous; Dextromethorphan; Dextrorphan; Infusion; Intrathecal; Memantine; Sheep

Indexed keywords

DEXTROMETHORPHAN; DEXTRORPHAN; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE CALCULATION; DOSE RESPONSE; DRUG SCREENING; FEMALE; HISTOPATHOLOGY; INTRATHECAL DRUG ADMINISTRATION; MALE; MOTOR DYSFUNCTION; NONHUMAN; RATING SCALE; SHEEP; TOXICITY TESTING;

EID: 0032696668     PISSN: 10947159     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1403.1999.00230.x     Document Type: Article

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