mAb against hen egg-white lysozyme regulate its presentation to CD4+ T cells

International Immunology

Volumn 11, Issue 11, 1999, Pages 1863-1872

  Guermonprez, Pierre ^a,b   Lo Man, Richard ^a,b   Sedlik, Christine ^a,b   Rojas, Marie Jesus ^a,b   Poljak, Roberto J ^a,b   Leclerc, Claude ^a,b  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

Author keywords

Antibodies; Antigen presentation; MHC class II

Indexed keywords

CD4 ANTIGEN; EPITOPE; LYSOZYME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY;

AMINO TERMINAL SEQUENCE; ANTIBODY AFFINITY; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME STRUCTURE; GERM LINE; IN VITRO STUDY; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; ANTIGEN-ANTIBODY COMPLEX; ANTIGEN-PRESENTING CELLS; CD4-POSITIVE T-LYMPHOCYTES; CHICKENS; EGG WHITE; EPITOPES; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS II; HYBRIDOMAS; LYMPHOMA, B-CELL; MICE; MURAMIDASE; RECEPTORS, FC; TUMOR CELLS, CULTURED;

EID: 0032692729     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/11.11.1863     Document Type: Article

References (39)

1. Lanzavecchia, A. 1985. Antigen-specific interaction between T and B cells. Nature 314:537.
2. Rock, K. L., Benacerraf, B. and Abbas, A. K. 1984. Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors. J. Exp. Med. 160:1102.
3. Celis, E. and Chang, T. W. 1984. Antibodies to hepatitis B surface antigen potentiate the response of human T lymphocyte clones to the same antigen. Science 224:297.
4. Manca, F., Fenoglio, D., Li Pira, G., Kunkl, A. and Celada, F. 1991. Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies. J. Exp. Med. 173:37.
5. Sallusto, F. and Lanzavecchia. A. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179:1109.
6. Esposito-Farese, M. E., Sautes, C., De la Salle, H., Latour, S., Bieber, T., De la Salle, C., Ohlmann, P., Fridman, W. H., Cazenave, J. P., Teillaud, J. L., Daëron, M., Bonnerot, C. and Hanau, D. 1995. Membrane and soluble Fc gamma RI/III modulate the antigen-presenting capacity of murine dendritic epidermal Langerhans cells and IgG-complexed antigens. J. Immunol. 155:1725.
7. Berzofsky, J. A. 1983. T-B reciprocity. An la-restricted epitope-specific circuit regulating T cell-B cell interaction and antibody specificity. Surv. Immunol. Res. 2:223.
8. Ozaki, S. and Berzofsky, J. A. 1987. Antibody conjugates mimic specific B cell presentation of antigen: relationship between T and B cell specificity. J. Immunol. 138:4133.
9. Manca, F., Fenoglio, D., Kunkl, A., Cambiaggi, C., Sasso, M. and Celada, F. 1988. Differential activation of T cell clones stimulated by macrophages exposed to antigen complexed with monoclonal antibodies. A possible influence of paratope specificity on the mode of antigen processing. J. Immunol. 140:2893.
10. Watts, C. and Lanzavecchia, A. 1993. Suppressive effect of antibody on processing of T cell epitopes. J. Exp. Med. 178:1459.
11. Simitsek, P. D., Campbell, D. G., Lanzavecchia, A., Fairweather, N. and Watts, C. 1995 Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants. J. Exp. Med. 181:1957.
12. Davidson, H. W. and Watts, C. 1989. Epitope-directed processing of specific antigen by B lymphocytes. J. Cell. Biol. 109:85.
13. Davidson, H. W., West, M. A. and Watts, C. 1990. Endocytosis, intracellular trafficking, and prpocessing of membrane IgG and monovalent antigen/membrane IgG complexes in B lymphocytes. J. Immunol. 144:4101.
14. Jemmerson, R. and Paterson, Y. 1986. Mapping epitopes on a protein antigen by the proteolysis of antigen-antibody complexes. Science 232:1001.
15. Tello, D., Goldbaum, F. A., Mariuzza, R. A., Ysern, X., Schwarz, F. P. and Poljak, R. J. 1993. Three-dimensional structure and thermodynamics of antigen binding by anti-lysozyme antibodies. Biochem. Soc. Trans. 21:943.
16. Amit, A. G., Mariuzza, R. A., Phillips, S. E. and Poljak, R. J. 1986. Three-dimensional structure of an antigen-antibody complex at 2.8 Å resolution. Science 233:747.
17. Chitarra, V, Alzari, P. M., Bentley, G. A., Bhat, T. N., Eisele, J. L., Houdusse, A., Lescar, J., Souchon, H. and Poljak, R. J. 1993. Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex. Proc. Natl Acad. Sci. 90:7711.
18. Bhat, T. N., Bentley, G. A., Boulot, G., Greene, M. I., Tello, D., Dall'Acqua, W., Souchon, H., Schwarz, F. P., Mariuzza, R. A. and Poljak, R. J. 1994. Bound water molecules and conformational stabilization help mediate an antigen-antibody association. Proc. Natl Acad. Sci. USA 91:1089.
19. Braden, B. C., Souchon, H., Eisele, J. L., Bentley, G. A., Bhat, T. N., Navaza, J. and Poljak, R. J. 1994. Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1. J. Mol. Biol. 243:767.
20. Lescar, J., Pellegrini, M., Souchon, H., Tello, D., Poljak, R. J., Peterson, N., Greene, M, and Alzari, P. M. 1995. Crystal structure of a cross-reaction complex between Fab F9.13.7 and guinea fowl lysozyme. J. Biol. Chem. 270:18067.
21. Schwarz, F. P., Tello, D., Goldbaum, F. A., Mariuzza, R. A. and Poljak, R. J. 1995. Thermodynamics of antigen-antibody binding using specific anti-lysozyme antibodies. Eur. J. Biochem. 228:388.
22. Lo-Man, R., Martineau, P., Betton, J. M., Hofnung, M. and Leclerc, C. 1994. Molecular context of a viral T cell determinant within a chimeric bacterial protein alters the diversity of its T cell recognition. J. Immunol. 152:5660.
23. Unkeless, J. C. 1979. Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors. J. Exp. Med. 150:580.
24. Amigorena, S., Bonnerot, C., Drake, J. R., Choquet, D., Hunziker, W., Guillet, J. G., Webster, P., Sautes, C., Mellman, I. and Fridman, W. H. 1992. Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes. Science 256:1808.
25. + T cell responses by antigens covalently linked to synthetic micro-spheres does not require adjuvant. Int. Immunol. 7:45.
26. Momburg, F., Fuchs, S., Drexler, J., Busch, R., Post, M., Hammerling, G. J. and Adorini, L. 1993. Epitope-specific enhancement of antigen presentation by invariant chain. J. Exp. Med. 178:1453.
27. Adorini, L., Guery, J. C., Fuchs, S., Ortiz-Navarrete, V., Hammerling, G. J. and Momburg, F. 1993. Processing of endogenously synthesized hen egg-white lysozyme retained in the endoplasmic reticulum or in secretory form gives rise to a similar but not identical set of epitopes recognized by class II-restricted T cells. J. Immunol. 151:3576.
28. Allen, P. M., Strydom, D. J. and Unanue, E. R. 1984. Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas. Proc. Natl Acad. Sci. USA 81:2489.
29. Tello, D., Spinelli, S., Souchon, H., Saul, A., Riottot, M. M., Mariuzza, R. A., Lascombe, M. B., Houdusse, A., Eiselé, J. L., Fischmann, T., Chitarra, V., Boulot, G., Bhat, T. N., Bentley, G. A., Alzari, P. M. and Poljak, R. J. 1990. Three dimensional structure and antigen binding specificity of antibodies. Biochimie 72:507.
30. Kenett, D. 1988. A simple ELISA for the classification of monoclonal antibodies according to their recognition of native epitopes. J. Immunol. Methods 106:203.
31. Unkeless, J. C., Scigliano, E. and Freedman, V. H. 1988. Structure and function of human and murine receptors for IgG. Ann. Revu. Immunol. 6:251.
32. Nadimi, F., Moreno, J., Momburg, F., Heuser, A., Fuchs, S., Adorini, L. and Hammerling, G. J. 1991. Antigen presentation of hen egg-white lysozyme but not of ribonuclease A is augmented by the major histocompatibility complex class II-associated invariant chain. Eur. J. Immunol. 21:1255.
33. Zhong, G., Romagnoli, P. and Germain, R. N. 1997. Related leucine-based cytoplasmic targeting signals in invariant chain and major histocompatibility complex class II molecules control endocytic presentation of distinct determinants in a single protein. J. Exp. Med. 185:429.
34. Griffin, J. P., Chu, R. and Harding, C. V. 1997. Early endosomes and a late endocytic compartment generate different peptide-class II MHC complexes via distinct processing mechanisms. J. Immunol 158:1523.
35. Amigorena, S. and Bonnerot, C. 1998. Role of B-cell and Fc receptors in the selection of T-cell epitopes. Curr. Opin. Immunol. 10:88.
36. Fridman, W. H., Bonnerot, C., Daeron, M., Amigorena, S., Teillaud, J. L. and Sautes, C. 1992. Structural bases of Fc gamma receptor functions. Immunol. Rev. 125:49.
37. Aluvihare, V. R., Khamlichi, A. A., Williams, G. T., Adorini, L. and Neuberger, M. S. 1997. Acceleration of intracellular targeting of antigen by the B-cell antigen receptor: importance depends on the nature of the antigen-antibody interaction. EMBO J., 16:3553.
38. Batista, F. D. and Neuberger, M. S. 1998. Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate. Immunity 8:751.
39. Williams, D. C., Jr., Benjamin, D. C., Poljak, R. J. and Rule, G. S. 1996. Global changes in amide hydrogen exchange rates for a protein antigen in complex with three different antibodies. J. Mol. Biol. 257:866.