Role of cytochrome P-450 4A in oxygen sensing and NO production in rat cremaster resistance arteries

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 277, Issue 4 46-4, 1999, Pages

  Kerkhof, Cornel J M ^a   Bakker, Erik N T P ^b   Sipkema, Pieter ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

17 octadecynoic acid; Arachidonic acid metabolism; Endothelium; Hypoxia; Spontaneous tone

Indexed keywords

ARACHIDONIC ACID; CYTOCHROME P450; HYDROXYICOSATETRAENOIC ACID; INDOMETACIN; LIPOXYGENASE; N(G) NITROARGININE; NITRIC OXIDE; NORDIHYDROGUAIARETIC ACID; OXYGEN; PROADIFEN; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTERY DIAMETER; ARTERY RESISTANCE; ARTICLE; BLOOD VESSEL TONE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CREMASTER MUSCLE; ENDOTHELIUM; HYPOXIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0032692373     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.277.4.h1546     Document Type: Article

References (38)

1. Bakker, E. N. T. P., and P. Sipkema. Permissive effect of nitric oxide in arachidonic acid induced dilation in isolated rat arterioles. Cardiovasc. Res. 38: 783-787, 1998.
2. Bolotina, V. M., S. Najibi, J. J. Palacino, P. J. Pagano, and R. A. Cohen. Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle. Nature 368: 850-853, 1994.
3. Brayden, J. E., and M. T. Nelson. Regulation of arterial tone by activation of calcium-dependent potassium channels. Science 256: 532-535, 1992.
4. Brown, I. P., C. I. Thompson, and F. L. Belloni. Role of nitric oxide in hypoxic coronary vasodilation in isolated perfused guinea pig heart. Am. J. Physiol. 264 (Heart Circ. Physiol. 33): H821-H829, 1993.
5. Busse, R., U. Förstermann, H. Matsuda, and U. Pohl. The role of prostaglandins in the endothelium-mediated vasodilatory response to hypoxia. Pflügers Arch. 401: 77-83, 1984.
6. Busse, R., U. Pohl, C. Kellner, and U. Klemm. Endothelial cells are involved in the vasodilatory response to hypoxia. Pflügers Arch. 397: 78-80, 1983.
7. Escalante, B., K. Omata, W. Sessa, S.-G. Lee, J. R. Falck, and M. L. Schwartzman. 20-Hydroxyeicosatetraenoic acid is an endothelium-dependent vasoconstrictor in rabbit arteries. Eur. J. Pharmacol. 235: 1-7, 1993.
8. O2. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H706-H715, 1994.
9. Graber, R., C. Sumida, and E. A. Nunez. Fatty acids and cell signal transduction. J. Lipid Mediat. Cell Signal. 9: 91-116, 1994.
10. Graser, T., and G. M. Rubanyi. Different mechanisms of hypoxic relaxation in canine coronary arteries and rat abdominal aortas. J. Cardiovasc. Pharmacol. 20, Suppl. 12: S117-S119, 1992.
11. Harder, D. R., D. Gebremedhin, J. Narayanan, C. Jefcoat, J. R. Falck, W. B. Campbell, and R. Roman. Formation and action of a P-450 4A metabolite of arachidonic acid in cat cerebral microvessels. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H2098-H2107, 1994.
12. Harder, D. R., A. R. Lange, D. Gebremedhin, E. K. Birks, and R. J. Roman. Cytochrome P450 metabolites of arachidonic acid as intracellular signaling molecules in vascular tissue. J. Vasc. Res. 34: 237-243, 1997.
13. Harder, D. R., J. Narayanan, E. K. Birks, J. F. Liard, J. D. Imig, J. H. Lombard, A. R. Lange, and R. J. Roman. Identification of a putative microvascular oxygen sensor. Circ. Res. 79: 54-61, 1996.
14. Hodgson, P. D., and K. W. Renton. The role of nitric oxide generation in interferon-evoked cytochrome P450 down-regulation. Int. J. Immunopharmacol. 17: 995-1000, 1995.
15. Jackson, W. F. Prostaglandins do not mediate arteriolar oxygen reactivity. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H1102-H1108, 1986.
16. Jackson, W. F. Regional differences in mechanism of action of oxygen on hamster arterioles. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H599-H603, 1993.
17. Kalsner, S. The effect of hypoxia on prostaglandin output on tone in isolated coronary arteries. Can. J. Physiol. Pharmacol. 55: 882-887, 1977.
18. Khatsenko, O. G., S. S. Gross, A. B. Rifkind, and J. R. Vane. Nitric oxide is a mediator of the decrease in cytochrome P450-dependent metabolism caused by immunostimulants. Proc. Natl. Acad. Sci. USA 90: 11147-11151, 1993.
19. O2 electrode with low flow dependency and fast response. Prog. Respir. Res. 3: 100-110, 1968.
20. Koller, A., D. Sun, A. Huang, and G. Kaley. Corelease of nitric oxide and prostaglandins mediates flow-dependent dilation of rat gracilis muscle arterioles. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H326-H332, 1994.
21. Lückhoff, A., and R. Busse. Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential. Pflügers Arch. 416: 305-311, 1990.
22. Makita, K., J. R. Falck, and J. H. Capdevila. Cytochrome P450, the arachidonic acid cascade, and hypertension: new vistas for an old enzyme system. FASEB J. 10: 1456-1463, 1996.
23. Meininger, G. A., K. L. Fehr, and M. B. Yates. Anatomic and hemodynamic characteristics of the blood vessels feeding the cremaster skeletal muscle in the rat. Microvasc. Res. 33: 81-97, 1987.
24. Messina, E. J., D. Sun, A. Koller, M. S. Wolin, and G. Kaley. Role of endothelium-derived prostaglandins in hypoxia-elicited arteriolar dilation in rat skeletal muscle. Circ. Res. 71: 790-796, 1992.
25. Messina, E. J., D. Sun, A. Koller, M. S. Wolin, G., and Kaley. Increases in oxygen tension evoke arteriolar constriction by inhibiting endothelial prostaglandin synthesis. Microvasc. Res. 48: 151-160, 1994.
26. Minamiyama, Y., S. Takemura, S. Imaoka, Y. Funae, Y. Tanimoto, and M. Inoue. Irreversible inhibition of cytochrome P450 by nitric oxide. J. Pharmacol. Exp. Ther. 283: 1479-1485, 1997.
27. Morgan, E. T. Regulation of cytochromes P450 during inflammation and infection. Drug Metab. Rev. 29: 1129-1188, 1997.
28. Muramatsu, M., Y. Iwama, K. Shimizu, H. Asano, Y. Toki, Y. Miyazaki, K. Okumura, H. Hashimoto, and T. Ito. Hypoxia-elicited contraction of aorta and coronary artery via removal of endothelium-derived nitric oxide. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H1339-H1347, 1992.
29. Ortiz de Montellano, P. R., and M. A. Correia. Cytochrome P450: Structure, Mechanism and Biochemistry. New York: Plenum, 1995, p. 305-364.
30. Park, K. H., L. E. Rubin, S. S. Gross, and R. Levi. Nitric oxide is a mediator of hypoxic coronary vasodilation. Relation to adenosine and cyclooxygenase-derived metabolites. Circ. Res. 71: 992-1001, 1992.
31. Pries, A. R, J. Heide, K. Ley, K. F. Klotz, and P. Gaehtgens. Effect of oxygen tension on regulation of arteriolar diameter in skeletal muscle in situ. Microvasc. Res. 49: 289-299, 1995.
32. Reid, J. M., A. G. Davies, F. M. Ashcroft, and D. J. Paterson. Effect of L-NMMA, cromakalim, and glibenclamide on cerebral blood flow in hypercapnia and hypoxia. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H916-H922, 1995.
33. Rubanyi, G. M., and P. M. Vanhoutte. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor. Am. J. Physiol. 250 (Heart Circ. Physiol. 19): H822-H827, 1986.
34. 2+ sensitivity and block. J. Physiol. (Lond.) 455: 601-621, 1992.
35. Schwartzman, M. L., J. R. Falck, P. Yadagiri, and B. Escalante. Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase: formation and identification of novel endothelium dependent vasoconstrictor metabolite. J. Biol. Chem. 264: 11658-11662, 1989.
36. 1-adrenoceptor constriction by acidosis and hypoxia in vitro. Am. J. Physiol. 268 (Heart Circ. Physiol. 37): H2068-H2076, 1995.
37. 2D-adrenergic receptor contraction of arteriolar smooth muscle and reversal of contraction by hypoxia. Circ. Res. 76: 53-63, 1995.
38. Xu, X.-P., M. A. Tanner, and P. R. Myers. Prostaglandin-mediated inhibition of nitric oxide production by bovine aortic endothelium during hypoxia. Cardiovasc. Res. 30: 345-350, 1995.