Cardiovascular disease

Novartis Foundation Symposium

Volumn 219, Issue , 1999, Pages 188-211

  Severs, Nicholas J ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAP JUNCTION PROTEIN; PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL; CARDIOVASCULAR DISEASE; CELL JUNCTION; CORONARY BLOOD VESSEL; HEART; HEART ARRHYTHMIA; HUMAN; IMMUNOLOGY; INJURY; METABOLISM; MOLECULAR GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; ARRHYTHMIA; CARDIOVASCULAR DISEASES; CONNEXINS; CORONARY VESSELS; GAP JUNCTIONS; HEART; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDES;

EID: 0032616427     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (48)

1. Andreeva ER, Serebryakov VN, Orekhov AN 1995 Gap junctional communication in primary culture of cells derived from human aortic intima. Tissue Cell 27:591-597
2. Angst BD, Khan LUR, Severs NJ et al 1997 Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium. Circ Res 80:88-94
3. Bastide B, Neyses L, Ganten D, Paul M, Willecke K, Traub O 1993 Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions. Circ Res 73:1138-1149
4. Beyer EC, Kistler J, Paul DL, Goodenough DA 1989 Antisera directed against connexin43 peptides react with a 43-kd protein localized to gap junctions in myocardium and other tissues. J Cell Biol 108:595-605
5. Blackburn JP, Peters NS, Yeh H-I, Rothery S, Green CR, Severs NJ 1995 Upregulation of connexin43 gap junctions during early stages of human coronary atherosclerosis. Arterioscler Thromb Vasc Biol 15:1219-1228
6. Bukauskas FF, Elfgang C, Willecke K, Weingart R 1995 Biophysical properties of gap junction channels formed by mouse connexin40 in induced pairs of transfected human HeLa cells. Biophys J 68:2289-2298
7. Campos De Carvalho AC, Masuda MO, Tanowitz HB, Winner M, Goldenberg RCS, Spray DC 1994 Conduction defects and arrhythmias in Chagas' disease: possible role of gap junctions and humoral mechanisms. J Cardiovasc Electrophysiol 5:686-698
8. Christ GJ, Spray DC, el-Sabban M, Moore LK, Brink PR 1996 Gap junctions in vascular tissues. Evaluating the role of intercellular communication in the modulation of vasomotor tone. Circ Res 79:631-646
9. Coppen SR, Dupont E, Rothery S, Severs NJ 1998 Connexin45 expression is preferentially associated with the ventricular conduction system in mouse and rat heart. Circ Res 82:232-243
10. Davis LM, Rodefeld ME, Green K, Beyer EC, Saffitz JE 1995 Gap junction protein phenotypes of the human heart and conduction system. J Cardiovasc Electrophysiol 6:813-822
11. Dupont E, Vozzi C, Coppen SR, Kaprielian RR, Severs NJ 1997 Connexin mRNA and protein expression is altered in human heart disease. J Mol Cell Cardiol 29:A108 (abstr)
12. Fujimoto K 1997 SDS-digested freeze-fracture replica labelling electron microscopy to study the two-dimensional distribution of integral membrane proteins and phospholipids in biomembrane: practical procedure, interpretation and application. Histochem Cell Biol 107:87-96
13. Goodenough DA, Simon AM, Paul DL 1999 Gap junctional intercellular communication in the mouse ovarian follicle. In: Gap junction-mediated intercellular signalling in health and disease. Wiley, Chichester (Novartis Found Symp 219) p 226-240
14. Gourdie RG, Green CR, Severs NJ 1991 Gap junction distribution in adult mammalian myocardium revealed by an antipeptide antibody and laser scanning confocal microscopy. J Cell Sci 99:41-55
15. Gourdie RG, Severs NJ, Green CR, Rothery S, Germroth P, Thompson RP 1993 The spatial distribution and relative abundance of gap-junctional connexin40 and connexin43 correlate to functional properties of the cardiac atrioventricular conduction system. J Cell Sci 105:985-991
16. Gros DB, Jongsma HJ 1996 Connexins in mammalian heart function. BioEssays 18:719-730
17. Gros DB, Jarry-Guichard T, ten Velde I et al 1994 Restricted distribution of connexin40, a gap junctional protein, in mammalian heart. Circ Res 74:839-851
18. Kanter HL, Saffitz JE, Beyer EC 1992 Cardiac myocytes express multiple gap junction proteins. Circ Res 70:438-444
19. Kaprielian RR, Gunning M, Dupont E et al 1998 Down-regulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle. Circulation 97:651-660
20. Ko Y-S, Yeh H-I, Rothery S et al 1997 Simultaneous localization of connexins 40, 37 and 43 in pulmonary artery endothelial gap junctions. In: Werner R (ed) Gap junctions. IOS Press, Amsterdam, p 183-187
21. Kocher O, Gabbiani F, Gabbiani G et al 1991 Phenotypic features of smooth muscle cells during the evolution of experimental carotid artery intimai thickening. Biochemical and morphologic studies. Lab Invest 65:459-470
22. Little TL, Xia J, Duling BR 1995a Dye tracers define differential endothelial and smooth muscle coupling patterns within the arteriolar wall. Circ Res 76:498-504
23. Little TL, Beyer EC, Duling BR 1995b Connexin 43 and connexin 40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivo. Am J Physiol 268:H729-H739
24. Matsushita T, Takahashi K, Yokoyama K, Takamatsu T 1996 Three dimensional and temporal expression of connexin43 in ischemic rat heart. Mol Biol Cell 7 (suppl):464a (abstr)
25. Mensink A, Brouwer A, Van den Burg EH et al 1996 Modulation of intercellular communication between smooth muscle cells by growth factors and cytokines. Eur J Pharmacol 310:73-81
26. Moore LK, Burt JM 1994 Selective block of gap junction channel expression with connexin-specific antisense oligodeoxynucleotides. Am J Physiol 267:C1371-C1380
27. Navab M, Ross LA, Hama S et al 1991 Interactions of human aortic wall cells in co-culture. Atheroscler Rev 23:153-160
28. Pepper MS, Montesano R, El Aoumari A, Gros D, Orci L, Meda P 1992 Coupling and connexin 43 expression in microvascular and large vessel endothelial cells. Am J Physiol 262:C1246-C1257
29. Peters NS, Green CR, Poole-Wilson PA, Severs NJ 1993 Reduced content of connexin43 gap junctions in ventricular myocardium from hypertrophied and ischaemic human hearts. Circulation 88:864-875
30. Peters NS, Severs NJ, Rothery SM, Lincoln C, Yacoub MH, Green CR 1994a Spatiotemporal relation between gap junctions and fascia adherens junctions during postnatal development of human ventricular myocardium. Circulation 90:713-725
31. Peters NS, Rowland E, Bennett JG, Green CR, Anderson RH, Severs NJ 1994b The Wolff-Parkinson-White syndrome: the cellular substrate for conduction in the accessory atrioventricular pathway. Eur Heart J 15:981-987
32. Peters NS, Severs NJ, Coromilas J, Wit AL 1997 Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia. Circulation 95:988-996
33. Rahimtoola SH 1989 The hibernating myocardium. Am Heart J 117:211-221
34. Reed KE, Westphale EM, Larson DM, Wang H-Z, Veenstra RD, Beyer EC 1993 Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. J Clin Invest 91:997-1004
35. Rennick RE, Connat J-L, Burnstock G, Rothery S, Severs NJ, Green CR 1993 Expression of connexin43 gap junctions between cultured vascular smooth muscle cells is dependent upon phenotype. Cell Tissue Res 271:323-332
36. Ross R 1995 Cell biology of atherosclerosis. Annu Rev Physiol 57:791-804
37. Saffitz JE, Hoyt RH, Luke RA, Kanter HL, Beyer EC 1992 Cardiac myocyte interconnections at gap junctions - role in normal and abnormal electrical conduction. Trends Cardiovasc Med 2:56-60
38. Saffitz JE, Davis LM, Darrow BJ, Kanter HL, Laing JG, Beyer EC 1995 The molecular basis of anisotropy; role of gap junctions. J Cardiovasc Electrophysiol 6:498-510
39. Sepp R, Severs NJ, Gourdie RG 1996 Altered patterns of cardiac intercellular junction distribution in hypertrophic cardiomyopathy. Heart 76:412-417
40. Severs NJ 1995 Freeze-fracture cytochemistry: an explanatory survey of methods. In: Severs NJ, Shotton DM (eds) Rapid freezing, freeze fracture and deep etching. Wiley-Liss Inc, New York, p 173-208
41. Severs NJ, Dupont E, Kaprielian RR et al 1996 Gap junctions and connexins in the cardiovascular system. In: Yacoub MH, Carpentier A, Pepper J et al (eds) Annual of cardiac surgery, 9th edn. Current Science, London, p 31-44
42. Smith JH, Green CR, Peters NS, Rothery S, Severs NJ 1991 Altered patterns of gap junction distribution in ischemic heart disease. An immunohistochemical study of human myocardium using laser scanning confocal microscopy. Am J Pathol 139:801-821
43. van Kempen MJ, ten Velde I, Wessels A et al 1995 Differential connexin distribution accommodates cardiac function in different species. Microsc Res Tech 31:420-436
44. Willecke K, Kirchhoff S, Plum A, Temme A, Thönnissen E, Ott T 1999 Biological functions of connexin genes revealed by human genetic defects, dominant negative approaches and targeted deletions in the mouse. In: Gap junction-mediated intercellular signalling in health and disease. Wiley, Chichester (Novartis Found Symp 219) p 76-96
45. Xie H, Hu VW 1994 Modulation of gap junctions in senescent endothelial cells. Exp Cell Res 214:172-176
46. Yeh H-I, Kanthou C, Dupont E, Lupu F, Severs NJ 1996 Differential effects of growth factors on gap junction expression in cultured human aortic smooth muscle cells. Eur Heart J 17 (suppl):397 (abstr)
47. Yeh H-I, Dupont E, Coppen S, Rothery S, Severs NJ 1997a Gap junction localization and connexin expression in cytochemically identified endothelial cells from arterial tissue. J Histochem Cytochem 45:539-550
48. Yeh H-I, Lupu F, Dupont E, Severs NJ 1997b Upregulation of connexin43 gap junctions between smooth muscle cells after balloon catheter injury in the rat carotid artery. Arterioscler Thromb Vase Biol 17:3174-3184