The influence of Lys68 in decapeptide agonists of C5a on C5a receptor binding, activation and selectivity

Journal of Peptide Research

Volumn 53, Issue 1, 1999, Pages 8-17

  Vogen, S M ^a   Finch, A M ^b   Wadi, S K ^b   Thatcher, J ^c   Monk, P N ^c   Taylor, S M ^b   Sanderson, Sam D ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Agonist receptor interactions; C5a; C5a agonists; C5a receptor

Indexed keywords

AMINO ACID RECEPTOR STIMULATING AGENT; ANAPHYLATOXIN; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; LYSINE; COMPLEMENT C5A, (65 74), TYR(65) PHE(67) PRO(69,71) ALA(73); COMPLEMENT C5A, (65-74), TYR(65)-PHE(67)-PRO(69,71)-ALA(73)-; COMPLEMENT RECEPTOR; LEUKOCYTE ANTIGEN; OLIGOPEPTIDE; PEPTIDE FRAGMENT; PEROXIDASE; SEROTONIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTERY MUSCLE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SPECIFICITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFLAMMATION; LEUKEMIA CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR UPREGULATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; CELL CULTURE; CHEMISTRY; DRUG EFFECT; DRUG POTENTIATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MUSCLE CONTRACTION; MUTATION; PROTEIN BINDING; SYNTHESIS; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

ANTIGENS, CD; CELLS, CULTURED; COMPLEMENT C5A; HUMANS; LYSINE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; MUTATION; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PEROXIDASE; PROTEIN BINDING; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, COMPLEMENT; SEROTONIN; TRANSFECTION;

EID: 0032609833     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-3011.1999.tb01612.x     Document Type: Article

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