메뉴 건너뛰기




Volumn 158, Issue 4, 1997, Pages 1670-1680

Anti-Human κ Opioid Receptor Antibodies: Characterization of Site-Directed Neutralizing Antibodies Specific for a Peptide κR(33-52) Derived from the Predicted Amino Terminal Region of the Human κ Receptor

Author keywords

[No Author keywords available]

Indexed keywords

ANTISERUM; BLOCKING ANTIBODY; IMMUNOGLOBULIN G; IMMUNOSUPPRESSIVE AGENT; KAPPA OPIATE RECEPTOR; MESSENGER RNA; PEPTIDE FRAGMENT;

EID: 0031568393     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (48)
  • 1
    • 0023522635 scopus 로고
    • Interactions between the neuroendocrine and immune systems: Common hormones and receptors
    • Weigent, D. A., and J. E. Blalock. 1987. Interactions between the neuroendocrine and immune systems: common hormones and receptors. Immunol. Rev. 100:79.
    • (1987) Immunol. Rev. , vol.100 , pp. 79
    • Weigent, D.A.1    Blalock, J.E.2
  • 2
    • 0027076873 scopus 로고
    • Opiates and immune function: Consequences on infectious diseases with special references to AIDS
    • Rouveix, B. 1988. Opiates and immune function: consequences on infectious diseases with special references to AIDS. Therapie 47:503.
    • (1988) Therapie , vol.47 , pp. 503
    • Rouveix, B.1
  • 3
    • 0024150430 scopus 로고
    • Opioid peptides and opioid receptors in cells of the immune system
    • Sibinga, N. E. S., and A. Goldstein. 1989. Opioid peptides and opioid receptors in cells of the immune system. Annu. Rev. Immunol. 6:219.
    • (1989) Annu. Rev. Immunol. , vol.6 , pp. 219
    • Sibinga, N.E.S.1    Goldstein, A.2
  • 4
    • 0023635489 scopus 로고
    • Interleukin 1 and interleukin 2 enhance proopiomelanocortin gene expression in pituitary cells
    • Brown, S. L., L. R. Smith, and J. E. Blalock. 1987. Interleukin 1 and interleukin 2 enhance proopiomelanocortin gene expression in pituitary cells. J. Immunol. 139:3181.
    • (1987) J. Immunol. , vol.139 , pp. 3181
    • Brown, S.L.1    Smith, L.R.2    Blalock, J.E.3
  • 5
    • 0024580681 scopus 로고
    • Interleukin 1 potentiates the secretion of β-endorphin induced secretagogues in the primary pituitary cell line (AtT-20)
    • Fagarasan, M. O., R. Eskay, and J. Axelrod. 1989. Interleukin 1 potentiates the secretion of β-endorphin induced secretagogues in the primary pituitary cell line (AtT-20). Proc. Natl. Acad. Sci. USA 86:2070.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 2070
    • Fagarasan, M.O.1    Eskay, R.2    Axelrod, J.3
  • 6
    • 0026077092 scopus 로고
    • The role of endogenous opioids and their receptors in the immune system
    • Carr, D. J. 1991. The role of endogenous opioids and their receptors in the immune system. Proc. Soc. Exp. Biol. Med. 198:710.
    • (1991) Proc. Soc. Exp. Biol. Med. , vol.198 , pp. 710
    • Carr, D.J.1
  • 9
    • 0022656036 scopus 로고
    • Effects of alpha-endorphin on the antigen-induced primary response of human blood B cells in vitro
    • Heijnen, C. J., C. Bevers, A. Kavelaars, and R. E. Ballieux. 1986. Effects of alpha-endorphin on the antigen-induced primary response of human blood B cells in vitro. J. Immunol. 136:213.
    • (1986) J. Immunol. , vol.136 , pp. 213
    • Heijnen, C.J.1    Bevers, C.2    Kavelaars, A.3    Ballieux, R.E.4
  • 10
    • 0025334005 scopus 로고
    • Suppression of B lymphocyte activation by β-endorphin
    • Morgan, E. L., M. R. McClurg, and J. A. Janda. 1990. Suppression of B lymphocyte activation by β-endorphin. J. Neuroimmunol. 28:209.
    • (1990) J. Neuroimmunol. , vol.28 , pp. 209
    • Morgan, E.L.1    McClurg, M.R.2    Janda, J.A.3
  • 11
    • 0029877211 scopus 로고    scopus 로고
    • Regulation of human B lymphocyte activation by opioid peptide hormones: Inhibition of IgG production by opioid receptor class (μ-, κ-, and, δ-) selective agonists
    • Morgan, E. L. 1996. Regulation of human B lymphocyte activation by opioid peptide hormones: inhibition of IgG production by opioid receptor class (μ-, κ-, and, δ-) selective agonists. J. Neuroimmunol. 65:21.
    • (1996) J. Neuroimmunol. , vol.65 , pp. 21
    • Morgan, E.L.1
  • 12
    • 0024674423 scopus 로고
    • Methionine-enkephalin stimulates in vitro proliferation of human peripheral lymphocytes via delta-opioid receptors
    • Hucklebridge, F. H., B. N. Hudspith, J. Muhamed, P. M. Lydyard, and J. Brostoff. 1989. Methionine-enkephalin stimulates in vitro proliferation of human peripheral lymphocytes via delta-opioid receptors. Brain Behav. Immun. 3:183.
    • (1989) Brain Behav. Immun. , vol.3 , pp. 183
    • Hucklebridge, F.H.1    Hudspith, B.N.2    Muhamed, J.3    Lydyard, P.M.4    Brostoff, J.5
  • 14
    • 0027379756 scopus 로고
    • Alpha adrenergic and mu-2 opioid receptors are involved in morphine-induced suppression of splenocyte natural killer activity
    • Carr, D. J., B. M. Gebhardt, and D. Paul. 1993. Alpha adrenergic and mu-2 opioid receptors are involved in morphine-induced suppression of splenocyte natural killer activity. J. Pharmacol. Exp. Ther. 264:1179.
    • (1993) J. Pharmacol. Exp. Ther. , vol.264 , pp. 1179
    • Carr, D.J.1    Gebhardt, B.M.2    Paul, D.3
  • 16
    • 0028815668 scopus 로고
    • Human granulocytes contain an opiate alkaloid-selective receptor mediating inhibition of cytokine-induced activation and chemotaxis
    • Makman, M. H., T. V. Bilfinger, and G. B. Stefano. 1995. Human granulocytes contain an opiate alkaloid-selective receptor mediating inhibition of cytokine-induced activation and chemotaxis. J. Immunol. 154:1323.
    • (1995) J. Immunol. , vol.154 , pp. 1323
    • Makman, M.H.1    Bilfinger, T.V.2    Stefano, G.B.3
  • 18
    • 0023229311 scopus 로고
    • Opioid mediated suppression of cultured peripheral blood mononuclear cell respiratory burst activity
    • Peterson, P. K., B. Sharp, G. Gekker, C. Brummitt, and W. F. Keane. 1987. Opioid mediated suppression of cultured peripheral blood mononuclear cell respiratory burst activity. J. Immunol. 138:3907.
    • (1987) J. Immunol. , vol.138 , pp. 3907
    • Peterson, P.K.1    Sharp, B.2    Gekker, G.3    Brummitt, C.4    Keane, W.F.5
  • 19
    • 0021182487 scopus 로고
    • Site-directed alkylation of multiple opioid receptors. I. Binding selectivity
    • James, I. F., and A. Goldstein. 1984. Site-directed alkylation of multiple opioid receptors. I. Binding selectivity. Mol. Pharmacol. 25:337.
    • (1984) Mol. Pharmacol. , vol.25 , pp. 337
    • James, I.F.1    Goldstein, A.2
  • 22
  • 23
    • 0028670235 scopus 로고
    • The human delta opioid receptor: Genomic organization, cDNA cloning, functional expression, and distribution in the human brain
    • Simonin, F., K. Befort, C. Gaveriaux-Ruff, H. Matthes, V. Nappey, B. Lannes, M. Micheletti, and B. Kieffer. 1994. The human delta opioid receptor: genomic organization, cDNA cloning, functional expression, and distribution in the human brain. Mol. Pharmacol. 26:1015.
    • (1994) Mol. Pharmacol. , vol.26 , pp. 1015
    • Simonin, F.1    Befort, K.2    Gaveriaux-Ruff, C.3    Matthes, H.4    Nappey, V.5    Lannes, B.6    Micheletti, M.7    Kieffer, B.8
  • 26
    • 0020658234 scopus 로고
    • U50,488H: A stereoactive and structurally novel non-mu (kappa) opioid agonist
    • Von Voitlander, P. F., R. A. Lahti, and J. H. Lunden. 1983. U50,488H: a stereoactive and structurally novel non-mu (kappa) opioid agonist. J. Pharmacol. Exp. Ther. 224:7.
    • (1983) J. Pharmacol. Exp. Ther. , vol.224 , pp. 7
    • Von Voitlander, P.F.1    Lahti, R.A.2    Lunden, J.H.3
  • 29
    • 0028984180 scopus 로고
    • Identication of kappa- And delta-opioid receptor transcripts in immune cells
    • Gaveriaux, P. J., F. Simonin, L. Laforet, and B. Kiefffer. 1995. Identication of kappa-and delta-opioid receptor transcripts in immune cells. FEBS Lett. 369:272.
    • (1995) FEBS Lett. , vol.369 , pp. 272
    • Gaveriaux, P.J.1    Simonin, F.2    Laforet, L.3    Kiefffer, B.4
  • 30
    • 0025009139 scopus 로고
    • Differential effect of opioids on immunoglobulin production by lymphocytes isolated from Peyer's patches and spleen
    • Carr, D. J., R. T. Radulescu, B. R. deCosta, K. C. Rice, and J. E. Blalock. 1990. Differential effect of opioids on immunoglobulin production by lymphocytes isolated from Peyer's patches and spleen. Life Sci. 47:1059.
    • (1990) Life Sci. , vol.47 , pp. 1059
    • Carr, D.J.1    Radulescu, R.T.2    DeCosta, B.R.3    Rice, K.C.4    Blalock, J.E.5
  • 31
    • 0024084144 scopus 로고
    • Regulation of human natural cytotoxicity by enkephalins and selective opiate antagonists
    • Oleson, D. R., and D. R. Johnson. 1988. Regulation of human natural cytotoxicity by enkephalins and selective opiate antagonists. Brain Behav. Immun. 2:171.
    • (1988) Brain Behav. Immun. , vol.2 , pp. 171
    • Oleson, D.R.1    Johnson, D.R.2
  • 32
    • 0019417380 scopus 로고
    • Polyclonal activation of human B lymphocytes by Fc fragments. I. Characterization of the cellular requirements for Fc fragment-mediated polyclonal antibody secretion by human peripheral blood B lymphocytes
    • Morgan, E. L., and W. O. Weigle. 1981. Polyclonal activation of human B lymphocytes by Fc fragments. I. Characterization of the cellular requirements for Fc fragment-mediated polyclonal antibody secretion by human peripheral blood B lymphocytes. J. Exp. Med. 154:778.
    • (1981) J. Exp. Med. , vol.154 , pp. 778
    • Morgan, E.L.1    Weigle, W.O.2
  • 33
    • 0028081049 scopus 로고
    • Decapeptide agonists of human C5a: The relationship between conformation and spasmogenic and platelet aggregatory responses
    • Sanderson, S. D., L. Kirnarsky, S. A. Sherman, J. A. Ember, A. M. Finch, and S. M. Taylor. 1994. Decapeptide agonists of human C5a: the relationship between conformation and spasmogenic and platelet aggregatory responses. J. Med. Chem. 38:3171.
    • (1994) J. Med. Chem. , vol.38 , pp. 3171
    • Sanderson, S.D.1    Kirnarsky, L.2    Sherman, S.A.3    Ember, J.A.4    Finch, A.M.5    Taylor, S.M.6
  • 35
    • 0027201170 scopus 로고
    • Anti-C5a receptor antibodies. I. Characterization of neutralizing antibodies specific for the human C5a receptor
    • Morgan, E. L., J. A. Ember, S. D. Sanderson, W. Scholz, R. Buchner, R. D. Ye, and T. E. Hugli. 1993. Anti-C5a receptor antibodies. I. Characterization of neutralizing antibodies specific for the human C5a receptor. J. Immunol. 151:377.
    • (1993) J. Immunol. , vol.151 , pp. 377
    • Morgan, E.L.1    Ember, J.A.2    Sanderson, S.D.3    Scholz, W.4    Buchner, R.5    Ye, R.D.6    Hugli, T.E.7
  • 36
    • 0024582457 scopus 로고
    • Induction of human B cell differentiation by Fc region activators. I. Identification of an active tetrapeptide
    • Hobbs, M. V., R. A. Houghten, J. A. Janda, W. O. Weigle, and E. L. Morgan. 1989. Induction of human B cell differentiation by Fc region activators. I. Identification of an active tetrapeptide. Clin. Immunol. Immunopathol. 50:251.
    • (1989) Clin. Immunol. Immunopathol. , vol.50 , pp. 251
    • Hobbs, M.V.1    Houghten, R.A.2    Janda, J.A.3    Weigle, W.O.4    Morgan, E.L.5
  • 40
    • 0029104269 scopus 로고    scopus 로고
    • The in vivo injection of antibodies direct against cloned mu opioid receptor blocked supraspinal analgesia induced by mu-agonists in mice
    • Garzon, J., and P. Sanchez-Blazquez. 1996. The in vivo injection of antibodies direct against cloned mu opioid receptor blocked supraspinal analgesia induced by mu-agonists in mice. Life Sci. 56:237.
    • (1996) Life Sci. , vol.56 , pp. 237
    • Garzon, J.1    Sanchez-Blazquez, P.2
  • 41
    • 0028866118 scopus 로고    scopus 로고
    • On the role of extracellular loops of opioid receptors in conferring ligand selectivity
    • Metzger, T. M., and D. M. Ferguson. 1996. On the role of extracellular loops of opioid receptors in conferring ligand selectivity. FEBS Lett. 375:1.
    • (1996) FEBS Lett. , vol.375 , pp. 1
    • Metzger, T.M.1    Ferguson, D.M.2
  • 42
    • 0028104682 scopus 로고
    • Differential binding domains of peptide and non-peptide ligands in cloned rat kappa opioid receptor
    • Xue, J. C., C. Chen, J. Zhu, S. Kunapuli, J. K. DeRiel, L. Yu, and L. Y. Liu-Chen. 1994. Differential binding domains of peptide and non-peptide ligands in cloned rat kappa opioid receptor. J. Biol. Chem. 269:30195.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30195
    • Xue, J.C.1    Chen, C.2    Zhu, J.3    Kunapuli, S.4    DeRiel, J.K.5    Yu, L.6    Liu-Chen, L.Y.7
  • 43
    • 0009600889 scopus 로고
    • A lymphocyte mRNA encodes the adrenocorticotropin/beta-lipotropin region of the proopiomelanocortin gene
    • Galin, F. S., R. D. LeBoeuf, and J. E. Blalock. 1990. A lymphocyte mRNA encodes the adrenocorticotropin/beta-lipotropin region of the proopiomelanocortin gene. Prog. Neuroendocrinol. 3:205.
    • (1990) Prog. Neuroendocrinol. , vol.3 , pp. 205
    • Galin, F.S.1    LeBoeuf, R.D.2    Blalock, J.E.3
  • 44
    • 0022459193 scopus 로고
    • Newcastle disease virus-infected splenocytes express the proopiomelanocortin gene
    • Westly, H. J., A. J. Kleiss, K. W. Kelley, P. K. Y. Wong, and P. K. Yuen. 1986. Newcastle disease virus-infected splenocytes express the proopiomelanocortin gene. J. Exp. Med. 163:1589.
    • (1986) J. Exp. Med. , vol.163 , pp. 1589
    • Westly, H.J.1    Kleiss, A.J.2    Kelley, K.W.3    Wong, P.K.Y.4    Yuen, P.K.5
  • 45
    • 0022493612 scopus 로고
    • Activation of mouse T-helper cells induce abundant preproenkephalin mRNA synthesis
    • Zurawski, G., M. Bebedik, B. J. Kamb, J. S. Abrams, S. M. Zurawski, and F. D. Lee. 1986. Activation of mouse T-helper cells induce abundant preproenkephalin mRNA synthesis. Science 232:772.
    • (1986) Science , vol.232 , pp. 772
    • Zurawski, G.1    Bebedik, M.2    Kamb, B.J.3    Abrams, J.S.4    Zurawski, S.M.5    Lee, F.D.6
  • 46
    • 0023026789 scopus 로고
    • Proenkephalin A-like mRNA in human leukemia lymphocytes and CNS-tissues
    • Monstein, H. J., J. R. Folksson, and L. Terenius. 1986. Proenkephalin A-like mRNA in human leukemia lymphocytes and CNS-tissues. Life Sci. 39.2237.
    • (1986) Life Sci. , vol.39 , pp. 2237
    • Monstein, H.J.1    Folksson, J.R.2    Terenius, L.3
  • 47
    • 0029019037 scopus 로고
    • Anti-inflammatory effects of kappa-opioids in adjuvant arthritis
    • Walker, J. S., C. R. Howlett, and V. Nayanar. 1995. Anti-inflammatory effects of kappa-opioids in adjuvant arthritis. Life Sci. 57:371.
    • (1995) Life Sci. , vol.57 , pp. 371
    • Walker, J.S.1    Howlett, C.R.2    Nayanar, V.3
  • 48
    • 0028474804 scopus 로고
    • Kappa-opioid receptor functions: Possible relevance to experimental allergic encephalomyelitis
    • Radulovic, J., D. Djergovic, C. Miljevic, and B. D. Jankovic. 1994. Kappa-opioid receptor functions: possible relevance to experimental allergic encephalomyelitis. Neuroimmunomodulation 4:236.
    • (1994) Neuroimmunomodulation , vol.4 , pp. 236
    • Radulovic, J.1    Djergovic, D.2    Miljevic, C.3    Jankovic, B.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.