Metabolism and biologic effects of 5-oxoeicosanoids on human neutrophils

Journal of Immunology

Volumn 156, Issue 1, 1996, Pages 336-342

  Powell, William S ^a   MacLeod, R John ^b   Gravel, Sylvie ^a   Gravelle, Francine ^a   Bhakar, Asha ^a  

^a MCGILL UNIVERSITY   (Canada)

^b RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; ICOSANOID; LEUKOTRIENE B4; LEUKOTRIENE B4 RECEPTOR;

ARACHIDONIC ACID METABOLISM; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; FATTY ACID OMEGA OXIDATION; HUMAN; HUMAN CELL; NEUTROPHIL; PRIORITY JOURNAL;

ARACHIDONIC ACIDS; CALCIUM; CELL MOVEMENT; CYTOSOL; HUMANS; LEUKOTRIENE B4; NEUTROPHILS; PERTUSSIS TOXIN; STEREOISOMERISM; TETRADECANOYLPHORBOL ACETATE; VIRULENCE FACTORS, BORDETELLA;

EID: 0030047022     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Borgeat, P , M. Hamberg, and B. Samuelsson. 1976. Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases. J. Biol. Chem. 251 7816.
2. Borgeat, P., and B. Samuelsson 1979. Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid. J. Biol Chem. 254:2643.
3. Borgeat, P., and B. Samuelsson. 1979. Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids Proc. Natl Acad. Sci. USA 76:3213.
4. 4 synthase activities. Proc. Natl. Acad. Sci USA 83-857.
5. Lewis, R A., E. J. Goetzl, J. M. Drazen, N. A. Soter, K. F. Austen, and E. J. Corey 1981. Functional characterization of synthetic leukotriene B and its stereochemical isomers J. Exp. Med 154:1243
6. 4 possess different biological potencies. Prostaglandins 21:143.
7. Sirois, P., S. Roy, G. Beraldin, P. Vallerand, and P. Borgeat 1982. Comparative activity of natural mono-, di- and tri-hydroxy derivatives of arachidonic acid on guinea-pig lungs: myotropic effect and stimulation of cyclooxygenase activity. Prostaglandins 24:405
8. 4 20-hydroxylase from polymorphonuclear leukocytes. J. Biol Chem. 259:3082.
9. Lindgren, J. Å., O Hansson, and B. Samuelsson. 1981 Formation of novel hydroxylated eicosatetraenoic acids in preparations of human polymorphonuclear leukocytes. FEBS Lett. 128:329.
10. 4 and its omega-oxidation products. Prostaglandins 25-29.
11. Goerzl, E , and W. Pickett. 1980. The human PMN leukocyte chemotactic activity of complex hydroxy-eicosatetraenoic acids (HETEs) J Immunol. 125:1789.
12. O'Flaherty, J , D, Jacobson, and J. Redman. 1988. Mechanism involved in the mobilization of neutrophil calcium by 5-hydroxyeicosatetraenoate. J. Immunol. 140.4323.
13. O'Flaherty, J., R. Wykle, J. Redman, M. Samuel, and M. Thomas. 1986. Metabolism of 5-hydroxyeicosatetraenoate by human neutrophils: production of a novel omega-oxidized derivative. J. Immunol. 137.3277.
14. 4 20-hydroxylase. J. Biol Chem 262:12421.
15. Maas, R. L. J. Turk, J. A. Oates, and A. R. Brash. 1982 Formation of a novel dihydroxy acid from arachidonic acid by lipoxygenase-catalyzed double oxygenation in rat mononuclear cells and human leukocytes. J. Biol. Chem. 257.7056.
16. Borgeat, P., S. Picard, P. Vallerand, and P Sirois 1981. Transformation of arachidonic acid in leukocytes. Isolation and structural analysis of a novel dihydroxy derivative. Prostaglandins Med. 6:557.
17. Powell, W. S , F. Gravelle, and S Gravel. 1992. Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxyeicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes. J Biol. Chem 267: 19233
18. Powell, W. S., F. Gravelle, and S. Gravel. 1994. Phorbol myristate acetate stimulates the formation of 5-oxo-6.8,11,14-eicosatetraenoic acid by human neutrophils by activating NADPH oxidase. J. Biol Chem. 269 25373
19. 4 receptor. J. Biol Chem 268:9280.
20. O'Flaherty, J. T., J. Cordes, J. Redman, and M. J Thomas. 1993. 5-Oxo-eicosatetraenoate, a potent human neutrophil stimulus. Biochem. Biophys. Res. Commun. 192:129.
21. O'Flaherty, J. T., J F. Cordes, S. L Lee, M Samuel, and M. J Thomas 1994. Chemical and biological characterization of oxo-eicosatetraenoic acids. Biochim. Biophys. Acta 1201:505.
22. Powell, W. S., D. Chung, and S. Gravel. 1995. 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human eosinophil migration. J. Immunol 154:4123.
23. Schwenk, U., E. Morita, R. Engel, and J. M. Schröder. 1992. Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid. J Biol. Chem. 267 12482
24. Schwenk, U , and J M. Schröder. 1995 5-Oxo-eicosanoids are potent eosinophil chemotactic factors-functional characterization and structural requirements. J. Biol. Chem. 270:15029
25. Powell, W. S. 1980. Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica. Prostaglandins 20:947
26. Boyum, A. 1968. Isolation of mononuclear cells and granulocytcs from human blood Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand. J Clin Lab. Invest. 21(Suppl. 97):77
27. Powell, W. S. 1987. Precolumn extraction and reversed-phase high-pressure liquid chromatography of prostaglandins and leukotrienes Anal. Biochem 164:117.
28. Powell, W. S., Y. Zhang, and S Gravel. 1994. Effects of phorbol myristatic acetate on the synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human polymorphonuclear leukocytes. Biochemistry 33:3927.
29. + channels. J. Biol. Chem 261:11520.
30. 2+ indicators with greatly improved fluorescence properties. J Biol. Chem. 260, 3440.
31. Falk, W., R. H. Goodwin, Jr., and E. J. Leonard. 1980. A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration J Immunol. Methods 33-239.
32. Sehmi, R., A. J. Wardlaw, O. Cromwell, K. Kunhara, P. Waltmann, and A B. Kay. 1992. Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects Blood 79.2952
33. Kay, A. B. 1970. Studies on eosinophil leucocyte migration. II. Factors specifically chemotactic for eosinophils and neutropluls generated from guinea-pig serum by antigen-antibody complexes. Clin. Exp Immunol. 7:723
34. Powell, W S , M. Hashefi, J. R. Falck, K. Chauhan, J. Rokach, S. S Wang, E Mills, and R. J MacLeod 1995. Effects of oxo and dihydro metabolites of 12-hydroxy-5,8,10,14-eicosatetraenoic acid on chemotaxis and cytosolic calcium levels in human neutrophils. J. Leukocyte Biol. 57:257.
35. 4, 12(R)- and 12(S)-hydroxyeicosatetraenoic acid in human neutrophils. Life Sci. 42.727
36. 4 from leukocyte membrane preparations by (12R)- and (12S)-hydroxyeicosatetraenoic acid. Biochim. Biophys Acta 917:406
37. 4 in cultured hepatoma cells and in human polymorphonuclear leukocytes-identification of a delta-6-reductase pathway. J. Biol Chem. 270:19845
38. Jubiz, W., O. Rådmark, C. Malmsten, G. Hansson, J. Å. Lindgren, J. Palmblad. A. M Udén, and B. Samuelsson. 1982. A novel leukotriene produced by stimulation of leukocytes with formylmethionylleucylphenylalanine. J. Biol. Chem 257:6106
39. Cunningham, F M., and P. M. Woollard. 1987. 12(R)-Hydroxy-5,8,10,14-eicosatetraenoic acid is a chemoattractant for human polymorphonuclear leucocytes in vitro. Prostaglandins 34:71
40. 4 metabolite. FEBS Lett 231. 385
41. 4 in the human lung. Biochem. Biophys. Res. Commun 170:23