Simulation and optimization of integrated bioprocesses: A case study

Journal of Chemical Technology and Biotechnology

Volumn 74, Issue 3, 1999, Pages 289-292

  Zhou, Y H ^a   Titchener Hooker, N J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; COMPUTER SIMULATION; FERMENTATION; MATHEMATICAL MODELS; OPTIMIZATION;

INTEGRATED BIOPROCESSES;

SOLVENT EXTRACTION;

EID: 0032590392     PISSN: 02682575     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4660(199903)74:3<289::AID-JCTB26>3.0.CO;2-#     Document Type: Article

References (10)

1. Kelly BD and Hatton TA, The fermentation/downstream processing interface. Bioseparation 1:333-349 (1991).
2. Gregory ME, Bulmer M, Bogle IDL and Titchener-Hooker NJ, Optimising enzyme production by bakers yeast in continuous culture: physiological knowledge useful for process design and control. Bioprocess Engineering 16:239-245 (1996).
3. Siddiqi SF, Titchener-Hooker NJ and Ayazi Shamlou P, Simulations of particle size distribution changes occurring during high-pressure disruption of bakers' years. Biotech and Bioeng 50:145-150 (1996).
4. Siddiqi SF, Bulmer M, Ayazi Shamlou P and Titchener-Hooker NJ, The effects of fermentation conditions on yeast cell debris particle size distribution during high pressure homogenisation. Bioprocess Engineering 14:1-8 (1995).
5. Pascal F, Dagot C, Pingaud H, Corriou JP, Pons MN and Engasser JM, Modelling of an industrial alcohol fermentation and simulation of the plant by a process simulator. Biotech and Bioeng 46:202-217 (1995).
6. Woodley JM and Titchener-Hooker NJ, The use of windows of operation as a bioprocess design tool. Bioprocess Engineering 14:263-268 (1996).
7. Eschenauer H, Koski J and Osyczha A, Multicriteria Design Optimisation: Procedures and Applications, Springer-Verlag, Berlin, Heidelberg (1990).
8. Shih CJ and Chang CJ, Pareto optimisation of alternative global criterion method for fuzzy structural design. Computer and Structures 54:455-460 (1995).
9. Zhou YH and Titchener-Hooker NJ, A study of the computer simulation for the design of integrated downstream bioprocess. Bioprocess Engineering 16:367-374 (1997).
10. Smilde AK, Knevelman A and Coenegracht PMJ, Introduction of multi-criteria decision-making in optimization procedures for high-performance liquid Chromatographic separations. Journal of Chromatography 369:1-10 (1986).