Isolation and identification of 1α-hydroxy-24-oxovitamin D3 and 1α,23-dihydroxy-24-oxovitamin D3: Metabolites of 1α,24(R)-dihydroxyvitamin D3 produced in rat kidney

Biochemical Pharmacology

Volumn 58, Issue 12, 1999, Pages 1965-1973

  Weinstein, Edward A ^a   Rao, D Sunita ^a   Siu Caldera, Mei Ling ^a   Tserng, Kou Yi ^b   Uskokovic, Milan R ^c   Ishizuka, Seiichi ^d   Reddy, G Satyanarayana ^d  

^a WOMEN AND INFANTS HOSPITAL   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c HOFFMANN LA ROCHE INC   (United States)

^d TEIJIN LTD   (Japan)

Author keywords

1 ,24(R)(OH)2D3; 1 ,25(OH)2D3; Hydroxylation; Kidney; Metabolism; Vitamin D3

Indexed keywords

COLECALCIFEROL DERIVATIVE; DRUG METABOLITE; TACALCITOL; 1 ALPHA,24 DIHYDROXYVITAMIN D3; 1 ALPHA,24-DIHYDROXYVITAMIN D3; 1 HYDROXY 24 OXOVITAMIN D3; 1,23 DIHYDROXY 24 OXOVITAMIN D3; 1,23-DIHYDROXY-24-OXOVITAMIN D3; 1-HYDROXY-24-OXOVITAMIN D3; CALCITRIOL; COLECALCIFEROL; DERMATOLOGICAL AGENT; DIHYDROXYCOLECALCIFEROL; DRUG DERIVATIVE;

ANIMAL TISSUE; ARTICLE; HYDROXYLATION; ISOLATED KIDNEY; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; VITAMIN D METABOLISM; ANIMAL; DRUG EFFECT; IN VITRO STUDY; ISOLATION AND PURIFICATION; KIDNEY; MASS SPECTROMETRY; METABOLISM; PERFUSION; SPRAGUE DAWLEY RAT; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; CALCITRIOL; CHOLECALCIFEROL; DERMATOLOGIC AGENTS; DIHYDROXYCHOLECALCIFEROLS; KIDNEY; MALE; MASS SPECTROMETRY; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032590076     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00293-2     Document Type: Article

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