Changes in hemoglobin concentration during chemoradiation of locally advanced head and neck tumors;Anderungen der hamoglobinkonzentration bei kombinierter radio- und chemotherapie lokal fortgeschrittener HNO-tumoren

Strahlentherapie und Onkologie

Volumn 175, Issue 11, 1999, Pages 559-562

  Lammering, Guido ^a,b   Carl, Ulrich Martin ^a   Pape, Hildegard ^a   Hartmann, Karl Axel ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b Dept of Psychiat and Hum Genetics   (United States)

Author keywords

Anemia; Head and neck cancer; Hemoglobin; Radio chemotherapy

Indexed keywords

CARBOPLATIN; CISPLATIN; FLUOROURACIL; HEMOGLOBIN; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIMETABOLITE;

ADULT; ADVANCED CANCER; AGED; ANEMIA; ARTICLE; ERYTHROCYTE TRANSFUSION; HEAD CANCER; HEMOGLOBIN DETERMINATION; HUMAN; MAJOR CLINICAL STUDY; MULTIMODALITY CANCER THERAPY; NECK CANCER; RADIATION INJURY; BLOOD; COMPARATIVE STUDY; FEMALE; HEAD AND NECK TUMOR; MALE; MIDDLE AGED; RADIATION DOSE; TIME;

ADULT; AGED; ANEMIA; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARBOPLATIN; CISPLATIN; COMBINED MODALITY THERAPY; FEMALE; FLUOROURACIL; HEAD AND NECK NEOPLASMS; HEMOGLOBINS; HUMANS; MALE; MIDDLE AGED; RADIOTHERAPY DOSAGE; TIME FACTORS;

EID: 0032589851     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000660050041     Document Type: Article

References (19)

1. Acht MJ van, Hermans J, Boks DE, et al. The prognostic value of hemoglobin and a decrease in hemoglobin during radiotherapy in laryngeal carcinoma. Radiother Oncol 1992;23:229-35.
2. Becker A, Stadler P, Hänsgen G, et al. Hemoglobin level influences the oxygenation status of squamous cell carcinoma of the head and neck (SC-CHN). Int J Radiat Oncol Biol Phys 1998;42:Suppl:2011.
3. Brizel M, Albers ME, Fisher SR, et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 1998;338:1798-804.
4. Bush RS. The significance of anemia in clinical radiation therapy. Int J Radiat Biol Phys 1986;12:2047-50.
5. Dunst J, Pigorsch S, Hänsgen G, et al. Low hemoglobin is associated with increased serum levels of vascular endothelial growth factor (VEGF) in cancer patients. Strahlenther Onkol 1999;175:93-6.
6. EORTC protocol Nr. 22931. A phase III randomized study on postoperative radio- and chemotherapy in patients with locally advanced head and neck carcinomas (not published).
7. Fietkau R, Baumann M, Becker A, et al. ARO96-3. Postoperative Strahlen- ± adjuvante 5-FU, Cis-Platin-Therapie bei operierten Kopf-Hals-Tumoren (nicht publiziert).
8. Frommhold H, Guttenberger R, Henke M. The impact of blood hemoglobin content on the outcome of radiotherapy. Strahlenther Onkol 1998;174:Suppl IV:31-4.
9. Gatenby RA, Kessler HB, Rosenblum JS, et al. Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int J Radiat Oncol Biol Phys 1988;14:831-8.
10. Grau C, Overgaard J. Significance of hemoglobin concentration for treatment outcome. In: Molls M, Vaupel P, eds. Blood perfusion and microenvironment of human tumours. Berlin-Heidelberg-New York: Springer, 1998:101-12.
11. Guttenberger R, Lutterbach J, Roth A, et al. Hemoglobin levels predict local regional control after postoperative radiotherapy for advanced head and neck cancer. Eur J Haematol 1997;33:Suppl:102-3.
12. Molls M, Stadler P, Becker A, et al. Relevance of oxygen in radiation oncology. Mechanisms of action, correlation to low hemoglobin levels. Strahlenther Onkol 1998;174:Suppl IV:13-6.
13. Munro AJ. An overview of randomised controlled trials of adjuvant chemotherapy in head and neck cancer. Br J Cancer 1995;71:83-91.
14. Nordsmark M, Overgaard M, Overgaard J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck. Radiother Oncol 1996;41:31-9.
15. Overgaard J. The influence of haemoglobin concentration on the response to radiotherapy. Scand J Clin Lab Invest 1988;48:49-53.
16. Stadler P, Becker A, Feldmann HJ, et al. The hypoxic subvolume influences the prognosis of head and neck cancer. Int J Radiat Oncol Biol Phys 1998;42:Suppl:45.
17. Tarnawski R, Skladowski K, Maciejewski B. Prognostic value of hemoglobin concentration in radiotherapy for cancer of supraglottic larynx. Int J Radiat Oncol Biol Phys 1997;38:1007-11.
18. Thomas L, Hrsg. Labor und Diagnose. Marburg: Medizinische Verlagsge-sellschaft, 1992:598.
19. World Health Organisation. WHO handbook for reporting results of cancer treatment. WHO Offset Publication No. 48. Geneva: WHO, 1979.