Brain penetration of the histamine H3 receptor antagonists thioperamide and clobenpropit in rat and mouse, determined with ex vivo [125I]iodophenpropit binding

Brain Research

Volumn 743, Issue 1-2, 1996, Pages 178-183

  Mochizuki, Takatoshi ^a,c   Jansen, Frank P ^c   Leurs, Rob ^c   Windhorst, Albert D ^c   Yamatodani, Atsushi ^b   Maeyama, Kazutaka ^a   Timmerman, Hendrik ^c  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

125I iodophenpropit; binding, ex vivo; brain penetration; clobenpropi t; histamine H3 receptor; mouse; rat; thioperamide

Indexed keywords

CLOBENPROPIT; HISTAMINE H3 RECEPTOR ANTAGONIST; THIOPERAMIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; SPECIES DIFFERENCE; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; BRAIN; CEREBRAL CORTEX; CORPUS STRIATUM; HISTAMINE ANTAGONISTS; IMIDAZOLES; IODINE RADIOISOTOPES; ISOTHIURONIUM; MALE; MICE; MICE, INBRED BALB C; PIPERIDINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; THIOUREA;

EID: 0030471997     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01040-2     Document Type: Article

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